Mass spectrometry-based metabolomics reveals metabolism of molnupiravir may lead to metabolic disorders and hepatotoxicity.

Autor: Chen J; Academician Workstation, Jiangxi University of Chinese Medicine, Nanchang, China.; Department of Gastroenterology & Hepatology, Laboratory of Hepato-intestinal Diseases and Metabolism, Frontiers Science Center for Disease-Related Molecular Network, and State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, Sichuan, China., Chen L; Academician Workstation, Jiangxi University of Chinese Medicine, Nanchang, China.; Department of Gastroenterology & Hepatology, Laboratory of Hepato-intestinal Diseases and Metabolism, Frontiers Science Center for Disease-Related Molecular Network, and State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, Sichuan, China., Li B; Academician Workstation, Jiangxi University of Chinese Medicine, Nanchang, China., Zhao Q; Department of Gastroenterology & Hepatology, Laboratory of Hepato-intestinal Diseases and Metabolism, Frontiers Science Center for Disease-Related Molecular Network, and State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, Sichuan, China., Cheng Y; Academician Workstation, Jiangxi University of Chinese Medicine, Nanchang, China.; Department of Gastroenterology & Hepatology, Laboratory of Hepato-intestinal Diseases and Metabolism, Frontiers Science Center for Disease-Related Molecular Network, and State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, Sichuan, China., Yan D; Academician Workstation, Jiangxi University of Chinese Medicine, Nanchang, China., Liu H; Academician Workstation, Jiangxi University of Chinese Medicine, Nanchang, China., Li F; Department of Gastroenterology & Hepatology, Laboratory of Hepato-intestinal Diseases and Metabolism, Frontiers Science Center for Disease-Related Molecular Network, and State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Publikováno v: Biomedical chromatography : BMC [Biomed Chromatogr] 2024 Nov; Vol. 38 (11), pp. e5996. Date of Electronic Publication: 2024 Aug 23.

Study of d ifferent heterocycles showing significant anti-severe acute respiratory syndrome 2 activity in vitro and in vivo.

Autor: Yengoyan, Aleksandr^1,2 ayengoyan@mail.ru, Gomktsyan, Tiruhi¹ tiruhi.gomktsyan@mail.ru, Pivazyan, Vergush¹ vergush.pivazyan.50@mail.ru, Ghazaryan, Emma¹ emma.ghazaryan.eg@gmail.com, Shainova, Roza¹ rozetta_11@mail.ru, Karapetyan, Armen¹ armkar@inbox.ru, Avetyan, Diana³ dina.avet@gmail.com, Aslanyan, Levon⁴ aslanyan.levon@gmail.com, Baroyan, Karine⁵ baroyankarine@mail.ru, Tuzikov, Alexander⁶ tuzikov@newman.bas-net.by, Sargsyan, Mariam⁷ mariam.sargsyan.1960@mail.ru, Baghdasaryan, Bagrat⁸ artdrbaghdasaryan@gmail.com, Bayramyan, Nane⁸ naneramaz@mail.ru, Hakobyan, Sona⁸ 777sona7@gmail.com, Poghosyan, Arpine⁸ arpi.poghosyan21@gmail.com, Avetisyan, Aida^8,9 a.avetis@mail.ru, Avagyan, Hranush^8,9 a.avagian@yahoo.com, Hakobyan, Lina⁸ lina.hakobyan@gmail.com, Zaven, Karalyan^8,9 zkaralyan@yahoo.com

Publikováno v: Veterinary World. Jun2024, Vol. 17 Issue 6, p1281-1290. 10p.

A Review of Hematological Complications and Treatment in COVID-19.

Autor: Yazdani, Armand N.¹, Abdi, Arian¹, Velpuri, Prathosh¹, Patel, Parth¹, DeMarco, Nathaniel¹, Agrawal, Devendra K.², Rai, Vikrant² vrai@westernu.edu

Publikováno v: Hematology Reports. Dec2023, Vol. 15 Issue 4, p562-577. 16p.

Simple Access to 3-(Hetero)arylated Derivatives of 2-Furoic Acid via Ru(II)-Catalyzed C3-H Arylation of 2-Furoylimidazole.

Autor: Shepelenko, Konstantin E., Gnatiuk, Irina G., Lavrentev, Igor V., Minyaev, Mikhail E., Chernyshev, Victor M., Ananikov, Valentine P.

Publikováno v: Synthesis; Oct2024, Vol. 56 Issue 19, p3063-3073, 11p

Development of Orally Bioavailable Bicyclic Pyrazolones as Inhibitors of Tumor Necrosis Factor-α Production

Autor: Clark, M. P., Laughlin, S. K., Laufersweiler, M. J., Bookland, R. G., Brugel, T. A., Golebiowski, A., Sabat, M. P., Townes, J. A., VanRens, J. C., Djung, J. F., Natchus, M. G., De, B., Hsieh, L. C., Xu, S. C., Walter, R. L., Mekel, M. J., Heitmeyer, S. A., Brown, K. K., Juergens, K., Taiwo, Y. O., Janusz, M. J.

Publikováno v: Journal of Medicinal Chemistry; May 2004, Vol. 47 Issue: 11 p2724-2727, 4p