Výsledky vyhledávání - "Natasza Kaczybura"

Synthesis of enantiomerically pure model compounds of the glucose-6-phosphate-T1-translocase inhibitors kodaistatins A–D. Inferences with regard to the stereostructure of the natural products

Autor: Thomas Wüster, Manfred Keller, Natasza Kaczybura, Reinhard Brückner

Publikováno v: Tetrahedron. 69:7785-7809

The kodaistatins A and C (5a,b) inhibit a step in glucose-metabolism at ∼100 nM concentrations. This makes them potential ‘leads’ in the therapy of diabetes. We elucidated the (S)-configuration of the side-chain stereocenter of kodaistatin A by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::61369eec6d845d8dec346f4576db8775
https://doi.org/10.1016/j.tet.2013.05.091

Zobrazit plný text záznamu

Tandem Claisen Condensation/Transesterification between Arylacetate Enolates and Arylmethylene-Substituted 2,2-Dimethyl-1,3-dioxolan-4-ones: An Improved Synthesis of Z-Configured Pulvinones

Autor: Natasza Kaczybura, Reinhard Brueckner

Publikováno v: Synthesis. 2007:118-130

Homer-Wadsworth-Emmons (HWE) alkenations of aromatic aldehydes with the novel phosphonate 24b led to E-configured arylmethylene-substituted 2,2-dimethyl-l,3-dioxolan-4-ones 25a-f (79-88% yield). The latter condensed with the lithium enolates of methy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11976f35bd378fca70d8caaf836c15a7
https://doi.org/10.1055/s-2006-950378

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání