Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Natasha Thawait"'
Autor:
Emma Jennings, Thomas A.E. Elliot, Natasha Thawait, Shivani Kanabar, Juan Carlos Yam-Puc, Masahiro Ono, Kai-Michael Toellner, David C. Wraith, Graham Anderson, David Bending
Publikováno v:
Cell Reports, Vol 33, Iss 5, Pp 108328- (2020)
Summary: Nr4a receptors are activated by T cell receptor (TCR) signaling and play key roles in T cell differentiation. Which TCR signaling pathways regulate Nr4a receptors and their sensitivities to TCR signal strength and duration remains unclear. U
Externí odkaz:
https://doaj.org/article/2a8552a3db8b42ca9b7d30801fa9df36
Autor:
Raquel Gil-Edo, German Hernández-Ribelles, Santiago Royo, Natasha Thawait, Alan Serrels, Miguel Carda, Eva Falomir
Publikováno v:
Gil-Edo, R, Hernández-Ribelles, G, Royo, S, Thawait, N, Serrels, A, Carda, M & Falomir, E 2023, ' Exploring BenzylethoxyAryl Urea Scaffolds for Multitarget Immunomodulation Therapies ', International Journal of Molecular Sciences, vol. 24, no. 10, pp. 8582 . https://doi.org/10.3390/ijms24108582
International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 8582
International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 8582
Thirteen benzylethoxyaryl ureas have been synthesized and biologically evaluated as multitarget inhibitors of VEGFR-2 and PD-L1 proteins to overcome resistance phenomena offered by cancer. The antiproliferative activity of these molecules on several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa59a383a1343ecb69ca4df2533ed17
https://doi.org/10.3390/ijms24108582
https://doi.org/10.3390/ijms24108582
Autor:
Adriana Flores-Langarica, Kendle M. Maslowski, Natasha Thawait, Thomas A.E. Elliot, Alastair Copland, David Bending, Emma K. Jennings, David A.J. Lecky, David C. Wraith
Publikováno v:
Immunity
Summary How T cell receptor (TCR) signal strength modulates T cell function and to what extent this is modified by immune checkpoint blockade (ICB) are key questions in immunology. Using Nr4a3-Tocky mice, we characterized early quantitative and quali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43037d602993e7db87f2fde608beb0a
https://pubmed.ncbi.nlm.nih.gov/34534438
https://pubmed.ncbi.nlm.nih.gov/34534438
Autor:
Natasha Thawait, Emma K. Jennings, Adriana Flores-Langarica, David Bending, David A.J. Lecky, Thomas A.E. Elliot, David C. Wraith
SummaryHow T cell receptor (TCR) signal strength modulates T cell function and to what extent this is modified by immune checkpoint blockade (ICB) are key questions in immunology. Using Nr4a3-Tocky mice as a digital read-out of NFAT pathway activity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::447dd01e9dfc4af98625d416b3530239
https://doi.org/10.1101/2021.03.02.431957
https://doi.org/10.1101/2021.03.02.431957
Autor:
David Bending, Emma K. Jennings, Natasha Thawait, Juan Carlos Yam-Puc, David C. Wraith, Shivani Kanabar, Kai-Michael Toellner, Graham Anderson, Thomas A.E. Elliot, Masahiro Ono
Publikováno v:
Cell Reports, Vol 33, Iss 5, Pp 108328-(2020)
Cell Reports
Cell Reports
Summary Nr4a receptors are activated by T cell receptor (TCR) signaling and play key roles in T cell differentiation. Which TCR signaling pathways regulate Nr4a receptors and their sensitivities to TCR signal strength and duration remains unclear. Us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6054e34df07cc18ff9a2001676a6283
http://www.sciencedirect.com/science/article/pii/S2211124720313176
http://www.sciencedirect.com/science/article/pii/S2211124720313176
Autor:
Emma K. Jennings, David Bending, Juan Carlos Yam-Puc, Graham Anderson, Shivani Kanabar, Masahiro Ono, Thomas A.E. Elliot, Kai-Michael Toellner, David C. Wraith, Natasha Thawait
SummaryNr4a receptors are activated by T cell receptor (TCR) and B cell receptor (BCR) signalling and play key roles in T cell differentiation and promoting T cell exhaustion. How TCR signalling pathways regulate Nr4a receptors and their sensitivitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5aa44cfb1e93423c1022f066efdca40