Výsledky vyhledávání - "Natasha T Wood"

Akademický článek

The influence of N-linked glycans on the molecular dynamics of the HIV-1 gp120 V3 loop.

Autor: Natasha T Wood, Elisa Fadda, Robert Davis, Oliver C Grant, Joanne C Martin, Robert J Woods, Simon A Travers

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e80301 (2013)

N-linked glycans attached to specific amino acids of the gp120 envelope trimer of a HIV virion can modulate the binding affinity of gp120 to CD4, influence coreceptor tropism, and play an important role in neutralising antibody responses. Because of

Externí odkaz: https://doaj.org/article/f277ad32ff404fd5bc0a742d50131f1a

Zobrazit plný text záznamu

Akademický článek

Trends in Genotypic HIV-1 Antiretroviral Resistance between 2006 and 2012 in South African Patients Receiving First- and Second-Line Antiretroviral Treatment Regimens.

Autor: Gert U Van Zyl, Tommy F Liu, Mathilda Claassen, Susan Engelbrecht, Tulio de Oliveira, Wolfgang Preiser, Natasha T Wood, Simon Travers, Robert W Shafer

Publikováno v: PLoS ONE, Vol 8, Iss 6, p e67188 (2013)

OBJECTIVESSouth Africa's national antiretroviral (ARV) treatment program expanded in 2010 to include the nucleoside reverse transcriptase (RT) inhibitors (NRTI) tenofovir (TDF) for adults and abacavir (ABC) for children. We investigated the associate

Externí odkaz: https://doaj.org/article/74015dd0882a41f9a24cdfaeb1228095

Zobrazit plný text záznamu

Structural Rearrangements Maintain the Glycan Shield of an HIV-1 Envelope Trimer After the Loss of a Glycan

Autor: Robert J. Woods, Simon A. Travers, Natasha T. Wood, Roux-cil Ferreira, Jeffrey R. Dorfman, Thandeka Moyo, Oliver C. Grant

Publikováno v: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)

The HIV-1 envelope (Env) glycoprotein is the primary target of the humoral immune response and a critical vaccine candidate. However, Env is densely glycosylated and thereby substantially protected from neutralisation. Importantly, glycan N301 shield

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aedacfd997c938d0bf10b6b04f273fcd
https://doi.org/10.1038/s41598-018-33390-2

Zobrazit plný text záznamu

Correction for Anthony et al., 'Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope'

Autor: Roux-Cil. Ferreria, David Matten, Colin Anthony, Penny L. Moore, Nigel Garrett, Lynn Morris, Valerie Bekker, Natasha T. Wood, Salim S. Abdool Karim, Talita. York, Carolyn Williamson, Philippe Selhorst

Publikováno v: Journal of Virology. 92

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8f6ab24f89f40d8687f07f0c5b77f1b
https://doi.org/10.1128/jvi.00243-18

Zobrazit plný text záznamu

Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope

Autor: Talita. York, Natasha T. Wood, Penny L. Moore, Salim S. Abdool Karim, David Matten, Philippe Selhorst, Nigel Garrett, Lynn Morris, Carolyn Williamson, Valerie Bekker, Colin Anthony, Roux-Cil. Ferreria

Publikováno v: Journal of Virology

V3-glycan-targeting broadly neutralizing antibodies (bNAbs) are a focus of HIV-1 vaccine development. Understanding the viral dynamics that stimulate the development of these antibodies can provide insights for immunogen design. We used a deep-sequen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b6e2825248008a6bc7f60d81d28d48
http://europepmc.org/articles/PMC5571269

Zobrazit plný text záznamu

Defining the human immunodeficiency virus type 1 transmission genetic bottleneck in a region with multiple circulating subtypes and recombinant forms

Autor: Gama Bandawe, Andile Nofemela, Leonard Maboko, Michael Hoelscher, Zenda Woodman, Ruwayhida Thebus, Natasha T. Wood, Jinny C. Marais, Carolyn Williamson, Oliver Hoffmann

Publikováno v: Virology. 415:107-113

The Mbeya region of Tanzania has a genetically complex HIV epidemic with multiple subtypes and recombinant forms circulating, together with a high frequency of dual infections with more than one subtype. This study aimed to determine whether this imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524c6a12f9e55ff0fbf0344fbb63ee2c
https://doi.org/10.1016/j.virol.2010.12.027

Zobrazit plný text záznamu

Adaptive changes in HIV-1 subtype C proteins during early infection are driven by changes in HLA-associated immune pressure

Autor: Winston Hide, Florette K. Treurnicht, Carolyn Williamson, Cathal Seoighe, Natasha T. Wood, D. P. Martin, Clive M. Gray, Helba Bredell, S. S. Abdool Karim, Zenda Woodman, Koleka Mlisana, Melissa-Rose Abrahams, D. de Assis Rosa

Publikováno v: Virology. 396(2):213-225

It is unresolved whether recently transmitted human immunodeficiency viruses (HIV) have genetic features that specifically favour their transmissibility. To identify potential “transmission signatures”, we compared 20 full-length HIV-1 subtype C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faebdea8f089bc001035dee51509f2b9

Zobrazit plný text záznamu

The Influence of N-Linked Glycans on the Molecular Dynamics of the HIV-1 gp120 V3 Loop

Autor: Robert Davis, Natasha T. Wood, Joanne C. Martin, Robert J. Woods, Elisa Fadda, Simon A. Travers, Oliver C. Grant

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 11, p e80301 (2013)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38783fae91a302d90551bc813032955f
http://europepmc.org/articles/PMC3841175

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání