Development of the First Tritiated Tetrazine: Facilitating Tritiation of Proteins

Autor: Natasha Shalina Radjani Bidesi, Umberto Maria Battisti, Sara Lopes van de Broek, Vladimir Shalgunov, Anne‐Mette Dall, Jesper Bøggild Kristensen, Dag Sehlin, Stina Syvänen, Gitte Moos Knudsen, Matthias Manfred Herth

Publikováno v: Radjani Bidesi, N S, Battisti, U M, Lopes van de Broek, S, Shalgunov, V, Dall, A-M, Bøggild Kristensen, J, Sehlin, D, Syvänen, S, Moos Knudsen, G & Herth, M M 2022, ' Development of the First Tritiated Tetrazine : Facilitating Tritiation of Proteins ', ChemBioChem, vol. 23, no. 23, e202200539 . https://doi.org/10.1002/cbic.202200539
ChemBioChem

Tetrazine (Tz)-trans-cyclooctene (TCO) ligation is an ultra-fast and highly selective reaction and it is particularly suited to label biomolecules under physiological conditions. As such, a 3 H-Tz based synthon would have wide applications for in vit

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