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pro vyhledávání: '"Natasha Seetharaman"'
Autor:
Gulenay Guner, Mirsad Mehaj, Natasha Seetharaman, Sherif Elashri, Helen F. Yao, Donald J. Clancy, Ecevit Bilgili
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2213 (2023)
The impacts of bead sizes and bead mixtures on breakage kinetics, the number of milling cycles applied to prevent overheating, and power consumption during the nanomilling of drug (griseofulvin) suspensions were investigated from both an experimental
Externí odkaz:
https://doaj.org/article/a23eaabc89924101bbcec95b1f2726a6
Publikováno v:
International journal of pharmaceutics. 624
Although heat is generated during the wet stirred media milling of drug suspensions, leading to notable temperature rise, a comprehensive analysis of heat generation does not exist. Hence, we investigated the impact of stirrer speed, bead loading, an
Autor:
Gulenay Guner, Sherif Elashri, Mirsad Mehaj, Natasha Seetharaman, Helen F. Yao, Donald J. Clancy, Ecevit Bilgili
Publikováno v:
Pharmaceutical research. 39(9)
Nanosuspensions have been used for enhancing the bioavailability of poorly soluble drugs. This study explores the temperature evolution during their preparation in a wet stirred media mill using a coupled experimental-enthalpy balance approach.Millin