Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Natasha R. Cerruti"'
Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole
Autor:
Natasha R. Cerruti, James R. Burgeson, Sean M. Amberg, Ryan A. Larson, Dongcheng Dai, Dima N. Gharaibeh, Dennis E. Hruby, Amy L. Moore, Tove' C. Bolken
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:744-749
A chemically diverse library of about 400,000 small molecules was screened for antiviral activity against lentiviral pseudotypes with the Lassa virus envelope glycoprotein (LASV GP) gene incorporated. High-throughput screening resulted in discovery o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1017e30fc2771db2e9602a7988ca5a9
https://doi.org/10.1016/j.bmcl.2012.11.095
https://doi.org/10.1016/j.bmcl.2012.11.095
Autor:
James R. Burgeson, Amy L. Moore, Dima N. Gharaibeh, Dongcheng Dai, Natasha R. Cerruti, Ryan A. Larson, Dennis E. Hruby, Sean M. Amberg
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:750-756
A series of potent arenavirus inhibitors sharing a benzimidazole core were previously reported by our group. SAR studies were expanded beyond the previous analysis, which involved the attached phenyl rings and methylamino linker portion, to include m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba2c2a1ff6ad85382b226d185033224
https://doi.org/10.1016/j.bmcl.2012.11.093
https://doi.org/10.1016/j.bmcl.2012.11.093
Autor:
Amy L. Moore, Dima N. Gharaibeh, Jordan K. Boutilier, Natasha R. Cerruti, Sean M. Amberg, Dongcheng Dai, Robert D. Allen, Candace Lovejoy, Shanthakumar R. Tyavanagimatt, Dennis E. Hruby, James R. Burgeson
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(13)
A series of acylthiourea derivatives were designed, synthesized, and evaluated for broad-spectrum antiviral activity with selected viruses from Poxviridae (vaccinia virus) and two different genera of the family Bunyaviridae (Rift Valley fever and La
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b2654ee429c361e5071a9034e67f30
https://pubmed.ncbi.nlm.nih.gov/22664128
https://pubmed.ncbi.nlm.nih.gov/22664128