The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects

Autor: Cécile Lecoeur, Philippe Froguel, Anne U. Jackson, Juan Ruiz, Guillaume Charpentier, Fritz F. Horber, Michael Boenhnke, Serge Hercberg, Beverley Balkau, Christine Cavalcanti-Proença, Martine Vaxillaire, Christian Dina, David Altshuler, Valgerdur Steinthorsdottir, Samy Hadjadj, Gudmar Thorleifsson, Natasha Potoczna, Franz Krempler, Kari Stefansson, David Meyre, Ronan Roussel, S. Maimaitiming, Stéphane Cauchi, Wolfgang Patsch, Hélène Choquet, Benjamin F. Voight, Leif Groop

Publikováno v: Human Molecular Genetics, vol. 18, no. 13, pp. 2495-2501
Choquet, Hélène; Cavalcanti-Proença, Christine; Lecoeur, Cécile; Dina, Christian; Cauchi, Stéphane; Vaxillaire, Martine; Hadjadj, Samy; Horber, Fritz; Potoczna, Natasha; Charpentier, Guillaume; Ruiz, Juan; Hercberg, Serge; Maimaitiming, Suliya; Roussel, Ronan; Boenhnke, Michael; Jackson, Anne U.; Patsch, Wolfgang; Krempler, Franz; Voight, Benjamin F.; Altshuler, David; ... (2009). The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects. Human molecular genetics, 18(13), pp. 2495-2501. Oxford University Press 10.1093/hmg/ddp169

A recent study reported an association between the brain natriuretic peptide (BNP) promoter T-381C polymorphism (rs198389) and protection against type 2 diabetes (T2D). As replication in several studies is mandatory to confirm genetic results, we ana

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