Zobrazeno 1 - 5
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pro vyhledávání: '"Natasha Pascoe"'
Publikováno v:
Open Biology, Vol 10, Iss 10 (2020)
Protein ubiquitination is a key post-translational modification that regulates diverse cellular processes in eukaryotic cells. The specificity of ubiquitin (Ub) signalling for different bioprocesses and pathways is dictated by the large variety of mo
Externí odkaz:
https://doaj.org/article/0466708df62a4f2f990cd593b4fba2d8
Publikováno v:
Open Biology, Vol 10, Iss 10 (2020)
Open Biology
Open Biology
Protein ubiquitination is a key post-translational modification that regulates diverse cellular processes in eukaryotic cells. The specificity of ubiquitin (Ub) signalling for different bioprocesses and pathways is dictated by the large variety of mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f746d4cc4f548ae3dbac1c75ef92fe
https://doi.org/10.1098/rsob.200279
https://doi.org/10.1098/rsob.200279
Autor:
Donna Tjandra, Frank Sicheri, Noah Manczyk, Maria Augusta Satori, Carsten Schwerdtfeger, Bradley B. Brasher, Sachdev S. Sidhu, Taras Makhnevych, Ashwin Seetharaman, Joan Teyra, Michael Costanzo, Charles Boone, Jason Moffat, Natasha Pascoe
Publikováno v:
Journal of molecular biology. 431(6)
We applied a yeast-two-hybrid (Y2H) analysis to screen for ubiquitin variant (UbV) inhibitors of a human deubiquitinase (DUB), ubiquitin-specific protease 2 (USP2). The Y2H screen used USP2 as the bait and a prey library consisting of UbVs randomized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7ab85c1adbe5709e6bc7acf5bd35f5
https://pubmed.ncbi.nlm.nih.gov/30763569
https://pubmed.ncbi.nlm.nih.gov/30763569
Autor:
Yizhao Tan, Natasha Pascoe, Elena Kuzmin, Carles Pons, Scott W. Simpkins, Maximilian Billmann, Matej Usaj, Jolanda van Leeuwen, Olga G. Troyanskaya, Zhen Yuan Lin, Erin B. Styles, Sara Sharifpoor, Bryan Joseph San Luis, Noël Malod-Dognin, Julia Hanchard, Claire Moore, Brenda J. Andrews, Igor Stagljar, Vuk Janjić, Anastasia Baryshnikova, Michael Costanzo, Susan D. Lee, Anne-Claude Gingras, Yiqun Chen, Chad L. Myers, Charles Boone, Sondra Bahr, Harsha Garadi Suresh, Benjamin VanderSluis, Jeff S. Piotrowski, Guihong Tan, Natasa Przulj, Jamie Snider, Emira Shuteriqi, Michael Boutros, Raamesh Deshpande, Adam P. Rosebrock, Christoph F. Kurat, Lars M. Steinmetz, Tharan Srikumar, Brian Raught, Wen Wang, Hiroki Okada, Justin Nelson, Sheena C. Li, Hongwei Zhu, Yoshikazu Ohya, Tian Xia, Zhijian Li, Nydia Van Dyk, Elizabeth N. Koch, Vicent Pelechano, Amy A. Caudy, Mojca Mattiazzi Usaj
Publikováno v:
Scopus-Elsevier
INTRODUCTION Genetic interactions occur when mutations in two or more genes combine to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic interaction occurs when two mutations, neither lethal individually, combine to ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a9bdf90476a0237f4356d3b09302d2
https://doi.org/10.1126/science.aaf1420
https://doi.org/10.1126/science.aaf1420