Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Natasha P. Degtyareva"'
Publikováno v:
Molecular and Cellular Biology. 28:5359-5368
Specific regions of genomes (fragile sites) are hot spots for the chromosome rearrangements that are associated with many types of cancer cells. Understanding the molecular mechanisms regulating the stability of chromosome fragile sites, therefore, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6ebb94a0bfa3b2ab05a1cf52dd96cf
https://doi.org/10.1128/mcb.02084-07
https://doi.org/10.1128/mcb.02084-07
Publikováno v:
Cell. 120(5):587-598
In the yeast Saccharomyces cerevisiae, reduced levels of the replicative α DNA polymerase result in greatly elevated frequencies of chromosome translocations and chromosome loss. We selected translocations in a small region of chromosome III and fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719f0a27058170a6d4b0d38537b3f183
Autor:
Joseph G. Culotti, Patricia W. Greenwell, Thomas D. Petes, Lijia Zhang, Natasha P. Degtyareva, Michael O. Hengartner, E. Randal Hofmann
Publikováno v:
Proceedings of the National Academy of Sciences. 99:2158-2163
Mismatch repair genes are important in maintaining the fidelity of DNA replication. To determine the function of the Caenorhabditis elegans homologue of the MSH2 mismatch repair gene ( msh-2 ), we isolated a strain of C. elegans with an insertion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7dabf2651a0c0f77d9d9134b85d529
https://doi.org/10.1073/pnas.032671599
https://doi.org/10.1073/pnas.032671599
Publikováno v:
Genetics. 152:47-59
Base selectivity, proofreading, and postreplication mismatch repair are important for replication fidelity. Because proofreading plays an important role in error correction, we have investigated factors that influence its impact in the yeast Saccharo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b8ff03b5b12cf37360ab2e5164d1d2
https://doi.org/10.1093/genetics/152.1.47
https://doi.org/10.1093/genetics/152.1.47
Publikováno v:
Cell. 120(5)
In the yeast Saccharomyces cerevisiae, reduced levels of the replicative alpha DNA polymerase result in greatly elevated frequencies of chromosome translocations and chromosome loss. We selected translocations in a small region of chromosome III and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::837b3e242e4a980db2677b06c6f79ed2
https://pubmed.ncbi.nlm.nih.gov/15766518
https://pubmed.ncbi.nlm.nih.gov/15766518