Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Natasha Neef"'
Autor:
Olivier Escaffre, Terry L. Juelich, Natasha Neef, Shane Massey, Jeanon Smith, Trevor Brasel, Jennifer K. Smith, Birte Kalveram, Lihong Zhang, David Perez, Tetsuro Ikegami, Alexander N. Freiberg, Jason E. Comer
Publikováno v:
Viruses, Vol 13, Iss 7, p 1388 (2021)
Currently there is no FDA-licensed vaccine or therapeutic against Sudan ebolavirus (SUDV) infections. The largest ever reported 2014–2016 West Africa outbreak, as well as the 2021 outbreak in the Democratic Republic of Congo, highlight the critical
Externí odkaz:
https://doaj.org/article/b7e6ee05ac214387bcee0e49e5b0ebf3
Autor:
Jason E. Comer, Olivier Escaffre, Natasha Neef, Trevor Brasel, Terry L. Juelich, Jennifer K. Smith, Jeanon Smith, Birte Kalveram, David D. Perez, Shane Massey, Lihong Zhang, Alexander N. Freiberg
Publikováno v:
Viruses, Vol 11, Iss 2, p 137 (2019)
The 2014 Ebolavirus outbreak in West Africa highlighted the need for vaccines and therapeutics to prevent and treat filovirus infections. A well-characterized small animal model that is susceptible to wild-type filoviruses would facilitate the screen
Externí odkaz:
https://doaj.org/article/cdfc26547a744ecaa612618eabb07600
Autor:
David Perez, Olivier Escaffre, Jeanon N. Smith, Lihong Zhang, Alexander N. Freiberg, Terry L. Juelich, Tetsuro Ikegami, Natasha Neef, Trevor Brasel, Shane Massey, Birte Kalveram, Jennifer K. Smith, Jason E. Comer
Publikováno v:
Viruses
Volume 13
Issue 7
Viruses, Vol 13, Iss 1388, p 1388 (2021)
Volume 13
Issue 7
Viruses, Vol 13, Iss 1388, p 1388 (2021)
Currently there is no FDA-licensed vaccine or therapeutic against Sudan ebolavirus (SUDV) infections. The largest ever reported 2014–2016 West Africa outbreak, as well as the 2021 outbreak in the Democratic Republic of Congo, highlight the critical
Autor:
Elizabeth F. McInnes, Natasha Neef
Publikováno v:
Toxicology Letters. 314:164-171
In routine regulatory toxicology studies, the anatomic pathology endpoints are frequently the most significant element of the study data. They may profoundly influence subsequent clinical development and use of a test article, with implications for b
Autor:
Birte Kalveram, Terry L. Juelich, Olivier Escaffre, Alexander N. Freiberg, David Perez, Natasha Neef, Jason E. Comer, Trevor Brasel, Jennifer K. Smith, Jeanon N. Smith, Lihong Zhang, Shane Massey
Publikováno v:
Viruses
Volume 11
Issue 2
Viruses, Vol 11, Iss 2, p 137 (2019)
Volume 11
Issue 2
Viruses, Vol 11, Iss 2, p 137 (2019)
The 2014 Ebolavirus outbreak in West Africa highlighted the need for vaccines and therapeutics to prevent and treat filovirus infections. A well-characterized small animal model that is susceptible to wild-type filoviruses would facilitate the screen
Autor:
Natasha Neef
Publikováno v:
Pathology of Toxicologists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f74d16c376f4aa870f8056e5fb9a005
https://doi.org/10.1002/9781118755174.ch8
https://doi.org/10.1002/9781118755174.ch8
Autor:
Natasha Neef
Publikováno v:
Toxicologic Pathology. 42:311-313
BACKGROUND Histopathology is one of the more subjective diagnostic tools used in human and veterinary medicine, and also one where levels of skill and experience can vary widely from one practitioner to another. This means that when this tool is tran
Publikováno v:
Comparative medicine. 65(3)
A 4-y-old female cynomolgus macaque presented for veterinary evaluation prior to placement in a preclinical study showed markedly low platelet counts that continued to decrease over time. Physical examination over the next several days showed areas o
Autor:
Norimitsu Shirai, Linda A. Chatman, Natasha Neef, John C. Pettersen, Karen Walters, John Litchfield, Jeffrey A. Pfefferkorn, Bradley E. Enerson, Stephen P. Schmidt
Publikováno v:
Toxicologic pathology. 42(4)
Glucokinase activators (GKAs) are being developed for the treatment of type 2 diabetes. The toxicity of 4 GKAs (PF-04279405, PF-04651887, piragliatin, and PF-04937319) was assessed in mice, rats, dogs, and/or monkeys. GKAs were administered for 2 to
Autor:
Rhys M. Jones, Natasha Neef
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 42(1)
The increasing use of poorly-soluble inhaled dry powder pharmaceuticals means that animal toxicology studies of these drugs frequently produce lung changes related to the physical presence of undissolved particulate material within the alveolar space