Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Natasha N Mott"'
Autor:
Magdalena M Przybycien-Szymanska, Natasha N Mott, Caitlin R Paul, Roberta A Gillespie, Toni R Pak
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18350 (2011)
Adolescence is a dynamic and important period of brain development however, little is known about the long-term neurobiological consequences of alcohol consumption during puberty. Our previous studies showed that binge-pattern ethanol (EtOH) treatmen
Externí odkaz:
https://doaj.org/article/1f005883ac9c49b5a2bec370a4cd7de1
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26647 (2011)
EtOH exposure in male rats increases corticotropin-releasing hormone (CRH) mRNA in the paraventricular nucleus of the hypothalamus (PVN), a brain region responsible for coordinating stress and anxiety responses. In this study we identified the molecu
Externí odkaz:
https://doaj.org/article/96c2adc7d22b48b0ae9b4e813a4c6dcc
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10143 (2010)
Fibroblast growth factors (FGFs) mediate a vast range of CNS developmental processes including neural induction, proliferation, migration, and cell survival. Despite the critical role of FGF signaling for normal CNS development, few reports describe
Externí odkaz:
https://doaj.org/article/c7261d22bc0a45f988a4cc2f5c3ff080
Publikováno v:
Journal of Neuroendocrinology. 27:861-871
Nuclear steroid hormone receptors are ubiquitously expressed transcription factors whose activity can be altered by post-translational modifications, such as phosphorylation. The consequences of post-translational modifications have been described fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf46c8221eb6d65ed0610f1c9e6c19f
https://doi.org/10.1111/jne.12326
https://doi.org/10.1111/jne.12326
Autor:
Xinli Yang, Cody L. Shults, Marc J. Glucksman, Yathindar S. Rao, Toni R. Pak, Magdalena M. Przybycien-Szymanska, Sarah A. Prins, Natasha N. Mott, Elena Pinceti, James L. Roberts
Publikováno v:
Molecular & Cellular Proteomics. 13:760-779
Recent clinical evidence suggests that the neuroprotective and beneficial effects of hormone therapy may be limited by factors related to age and reproductive status. The patient's age and length of time without circulating ovarian hormones are likel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19613c415170e87f17400f111ef74183
https://doi.org/10.1074/mcp.m113.031559
https://doi.org/10.1074/mcp.m113.031559
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 465:655-667
Over the past 20 years our understanding of the basic mechanisms of gene regulation has vastly expanded due to the unexpected roles of small regulatory RNAs, in particular, microRNAs (miRNAs). miRNAs add another layer of complexity to the regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46e3a7bf25e4ca93b92d4ac170fecd4
https://doi.org/10.1007/s00424-013-1227-y
https://doi.org/10.1007/s00424-013-1227-y
Autor:
Natasha N. Mott, Toni R. Pak
Publikováno v:
Journal of Neuroendocrinology. 24:1311-1321
Oestrogen receptor (ER)α and ERβ are members of the ligand-activated superfamily of nuclear receptors and mediate most facets of oestrogen signalling. Several naturally occurring splice variants of each ER have been identified in the human brain, y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12f98b2ec866e617fc8e7110c82ffac4
https://doi.org/10.1111/j.1365-2826.2012.02337.x
https://doi.org/10.1111/j.1365-2826.2012.02337.x
Publikováno v:
Endocrine. 39:220-228
The hypothalamo-pituitary-adrenal (HPA) and hypothalamo-pituitary-gonadal (HPG) axes have an intricate cross talk that results in the inhibition of reproductive functions during periods of chronic physiological or psychological stress. Recent studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8ffb4d86acfc82b6e2a0855b92358c
https://doi.org/10.1007/s12020-011-9439-4
https://doi.org/10.1007/s12020-011-9439-4
Publikováno v:
Endocrinology. 154(8)
Menopause is characterized by the rapid age-related decline of circulating 17β-estradiol (E2) levels in women, which can sometimes result in cognitive disorders such as impaired memory and increased anxiety. Hormone therapy (HT) is a widely used tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7f63f35d0a398afc1b5bad3594629f
https://pubmed.ncbi.nlm.nih.gov/23873768
https://pubmed.ncbi.nlm.nih.gov/23873768
Autor:
Toni R. Pak, Natasha N. Mott
Publikováno v:
ISRN Endocrinology
Recent clinical studies have spurred rigorous debate about the benefits of hormone therapy (HT) for postmenopausal women. Controversy first emerged based on a sharp increase in the risk of cardiovascular disease in participants of the Women’s Healt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604c134563038d1fe69bc187ecddbd57
https://pubmed.ncbi.nlm.nih.gov/23936665
https://pubmed.ncbi.nlm.nih.gov/23936665