Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Natasha Luquin"'
Autor:
Kirsten C. Morley, Henry R. Kranzler, Natasha Luquin, Andrew Baillie, Marian Shanahan, Ronald Trent, Maree Teesson, Paul S. Haber
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Current treatments for alcohol use disorders have limited efficacy and there is a high degree of variability in treatment response. In a randomised, placebo-controlled clinical trial, there was a large effect size for topiramate i
Externí odkaz:
https://doaj.org/article/719c5ee863444304b5a2c45ff93f4ea4
Autor:
Natasha Luquin, Salvador Sierra, Alberto J. Rico, Virginia Gómez-Bautista, Elvira Roda, Lorena Conte-Perales, Rafael Franco, Peter McCormick, José L. Labandeira-García, José L. Lanciego
Publikováno v:
Neurobiology of Disease, Vol 47, Iss 3, Pp 347-357 (2012)
The A2AR has become a therapeutic target in Parkinson disease due to its functional role in the striatum, capable of modulating dopaminergic neurotransmission in the basal ganglia. No conclusive evidence, however, has been provided to demonstrate the
Externí odkaz:
https://doaj.org/article/2c44aac8f5424673bf2f1dde257e6737
Autor:
Nazila Jamshidi, Akshay Athavale, Christopher Tremonti, Catherine McDonald, Shanmugam Banukumar, Santiago Vazquez, Natasha Luquin, Marina Santiago, Bridin Murnion
Publikováno v:
British journal of clinical pharmacologyREFERENCES.
Buprenorphine is effective at reducing relapse to opioid misuse, morbidity and mortality in opioid-dependent patients. Urine drug screening (UDS) to assess adherence is used routinely in opioid agonist treatment (OAT). The primary aim of this study w
Publikováno v:
Clinical Autonomic Research. 28:35-52
Cardiovascular disease is now recognized as the number one cause of death in the world, and the size of the population at risk continues to increase rapidly. The dysregulation of the endocannabinoid (eCB) system plays a central role in a wide variety
Autor:
Kirsten C, Morley, Natasha, Luquin, Andrew, Baillie, Isabel, Fraser, Ronald J, Trent, Glenys, Dore, Nghi, Phung, Paul S, Haber
Publikováno v:
Addiction (Abingdon, England). 113(12)
Baclofen has been shown to reduce alcohol consumption in alcohol-dependent individuals, but there is marked heterogeneity in response. An association between GABBR1 rs29220 and alcohol dependence has been demonstrated previously. The present study ev
Publikováno v:
Journal of the Neurological Sciences. 357:326-328
Publikováno v:
Muscle & Nerve. 44:492-498
Introduction: Most analyses of blood DNA in sporadic neuromuscular disorders have been inconclusive. This may be because some genetic variants occur only in brain tissue. We therefore looked for copy number variants (CNVs) in both blood and brain in
Publikováno v:
Amyotrophic Lateral Sclerosis. 11:76-82
Somatic mutations have been suggested as a cause of sporadic amyotrophic lateral sclerosis (SALS). These mutations can be difficult to detect since they may involve only a small percentage of cells within the tissue, so we devised a method to detect
Publikováno v:
Neuropathology and Applied Neurobiology. 35:222-225
Autor:
John Mitrofanis, Natasha Luquin
Publikováno v:
Parkinsonism & Related Disorders. 14:213-223
We have explored the survival of dopaminergic cells of the substantia nigra pars compacta (SNc) in 6 hydroxydopamine (6OHDA)-lesioned rats with prior cortical removal. There were approximately 35% more dopaminergic cells in the ventral sector of SNc