Výsledky vyhledávání - "Natasha L. Martin"

Safety and Immunogenicity of HIV Recombinant Envelope Vaccines in HIV-Infected Infants and Children

Publikováno v: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 19:451-461

Study objectives were to evaluate the safety and immunogenicity of three HIV recombinant glycoproteins in HIV-infected infants and children between 1 month and 18 years of age with asymptomatic (P-1) infection. Using Chiron rgp 120 (SF-2) 15 or 50 mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b03236fb6cc1b4f4153ab66f6694411e
https://doi.org/10.1097/00042560-199812150-00003

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Low number of antibody producing cells in patients with sickle cell anemia

Autor: Natasha L. Martin, Yolanda Rooks, William C. Mentzer, Jukka Rautonen, Nina Rautonen, Diane W. Wara

Publikováno v: Immunology Letters. 34:207-211

B cell function is impaired in patients with sickle cell anemia. Although the number of surface IgM positive cells was similar in sickle cell patients and controls, in vitro spontaneous IgM, and PWM stimulated IgA, IgM, and IgG synthesis was signific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262e875a4b9d01f080a5f94ed1db32dd
https://doi.org/10.1016/0165-2478(92)90215-a

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A Screening Test for the Detection of Anti-Hiv-1 IgA in Young Infants

Autor: Diane W. Wara, Natasha L. Martin, Jukka Rautonen, William R. Crombleholme, Nina Rautonen

Publikováno v: Immunological Investigations. 21:65-70

A simple dot blot screening test for anti-HIV-1 IgA in infant sera was developed using recombinant HIV proteins. Ten control infants, 19 uninfected infants of seropositive mothers and 12 HIV culture positive infants were studied at 3 month and 18 mon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2f854cf141339507cc134691205ca0
https://doi.org/10.3109/08820139209069363

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Detection of infection with human immunodeficiency virus (HIV) type 1 in infants by an anti-HIV immunoglobulin A assay using recombinant proteins

Autor: Jay A. Levy, Morton J. Cowan, Peggy S. Weintrub, Harold Legg, Natasha L. Martin, Diane W. Wara

Publikováno v: The Journal of Pediatrics. 118:354-358

To diagnose infection with the human immunodeficiency virus (HIV) soon after birth in infants born to HIV type 1-infected women, we developed antiviral IgA Western blot and dot blot assays with recombinant HIV-1 proteins. Thirty-three infants born to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506902f7abb8c3730ab2841694654376
https://doi.org/10.1016/s0022-3476(05)82146-8

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Immunological correlates of disease severity in pediatric slow progressors with human immunodeficiency virus type 1 infection

Autor: Mary Ann Fletcher, Roberto Patarca, Natasha L. Martin, Nancy G. Klimas, Gwendolyn B. Scott, Kevin Maher, Cecelia Hutto, Dmitry Sandler

Publikováno v: AIDS research and human retroviruses. 12(11)

Pediatric slow progressors are a group of HIV-1-infected individuals who are homogeneous for route and length of infection and standard of care and are therefore amenable to cross-sectional population studies on the immunological correlates of diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1bb2cc34f485d930a1c7e473c9569fd
https://pubmed.ncbi.nlm.nih.gov/8827222

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HIV type 1 Tat protein induces immunoglobulin and interleukin 6 synthesis by uninfected peripheral blood mononuclear cells

Autor: Natasha L. Martin, Nina Rautonen, Jukka Rautonen, Diane W. Wara

Publikováno v: AIDS research and human retroviruses. 10(7)

Tat is a potent trans-activating protein encoded by the HIV genome. It is essential for viral replication, but has pleiotropic effects on host cells as well. We demonstrated that exogenous recombinant Tat increases immunoglobulin (Ig) and interleukin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2cbf2a3a226014cfbd70ae94f8b7849
https://pubmed.ncbi.nlm.nih.gov/7986583

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Serum levels of soluble CD8, neopterin, beta 2-microglobulin and p24 antigen as indicators of disease progression in children with AIDS on zidovudine therapy

Autor: Su Chun Cheng, Jukka Rautonen, Natasha L. Martin, Leila Siller, Laurel A. Beckett, Diane W. Wara, Paul Kostuchenko

Publikováno v: AIDS (London, England). 7(3)

Objective To test the hypothesis that serum levels of soluble markers in children change after initiation of zidovudine therapy and that the extent and pattern of these longitudinal changes correlates with clinical outcome. Patients and methods We me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d572ecaa4de10437c351915fded6cff8
https://pubmed.ncbi.nlm.nih.gov/8097095

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Serum interleukin-6 concentrations are elevated and associated with elevated tumor necrosis factor-alpha and immunoglobulin G and A concentrations in children with HIV infection

Autor: Jukka Rautonen, Natasha L. Martin, Ramila Philip, Nina Rautonen, Diane W. Wara

Publikováno v: AIDS (London, England). 5(11)

Hypergammaglobulinemia is one of the most consistent, and usually the first observable abnormality in infants vertically infected with HIV. We have analyzed serum interleukin (IL)-4, IL-6, tumor necrosis factor (TNF)-alpha, and immunoglobulin (Ig) co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e56d8e9008a131e2a04de56edc1b69
https://pubmed.ncbi.nlm.nih.gov/1768380

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