Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Natasha L Harvey"'
Autor:
Lin Grimm, Hiroyuki Nakajima, Smrita Chaudhury, Neil I Bower, Kazuhide S Okuda, Andrew G Cox, Natasha L Harvey, Katarzyna Koltowska, Naoki Mochizuki, Benjamin M Hogan
Publikováno v:
eLife, Vol 8 (2019)
Lymphatic vascular development involves specification of lymphatic endothelial progenitors that subsequently undergo sprouting, proliferation and tissue growth to form a complex second vasculature. The Hippo pathway and effectors Yap and Taz control
Externí odkaz:
https://doaj.org/article/939477b57dd243f285d6fad89559ef17
Autor:
Anna E. Williamson, Sanuri Liyanage, Mohammadhossein Hassanshahi, Malathi S. I. Dona, Deborah Toledo-Flores, Dang X. A. Tran, Catherine Dimasi, Nisha Schwarz, Sanuja Fernando, Thalia Salagaras, Aaron Long, Jan Kazenwadel, Natasha L. Harvey, Grant R. Drummond, Antony Vinh, Vashe Chandrakanthan, Ashish Misra, Zoltan Neufeld, Joanne T. M. Tan, Luciano Martelotto, Jose M. Polo, Claudine S. Bonder, Alexander R. Pinto, Shiwani Sharma, Stephen J. Nicholls, Christina A. Bursill, Peter J. Psaltis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Converging evidence indicates that extra-embryonic yolk sac is the source of both macrophages and endothelial cells in adult mouse tissues. Prevailing views are that these embryonically derived cells are maintained after birth by proliferati
Externí odkaz:
https://doaj.org/article/d2b62685f49a4c7f8deedee2fe7c08c9
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40497 (2012)
Despite the importance of blood vessels and lymphatic vessels during development and disease, the signalling pathways underpinning vessel construction remain poorly characterised. Primary mouse endothelial cells have traditionally proven difficult to
Externí odkaz:
https://doaj.org/article/f8be11870cf94785bd04f79fb921b110
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9377 (2010)
The homeobox gene Prox1 is required for lens, retina, pancreas, liver, and lymphatic vasculature development and is expressed in inner ear supporting cells and neurons.We have investigated the role of Prox1 in the developing mouse ear taking advantag
Externí odkaz:
https://doaj.org/article/79c844013a0645e8a17d74c502e30eaf
Autor:
Iman Lohraseb, Peter McCarthy, Genevieve Secker, Ceilidh Marchant, Jianmin Wu, Naveid Ali, Sharad Kumar, Roger J. Daly, Natasha L. Harvey, Hiroshi Kawabe, Oded Kleifeld, Sophie Wiszniak, Quenten Schwarz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Here the authors combine multi-omics approaches to uncover a role for ubiquitination and the ubiquitin ligase NEDD4 in targeting the actin binding protein Profilin 1 to regulate actin polymerisation in neural crest cells.
Externí odkaz:
https://doaj.org/article/b39a1c0a20ae4ebda1ec3a9f3cfebfb7
Publikováno v:
Nature Cardiovascular Research. 2:193-195
Autor:
Genevieve A. Secker, Natasha L. Harvey
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7760 (2021)
The importance of lymphatic vessels in a myriad of human diseases is rapidly gaining recognition; lymphatic vessel dysfunction is a feature of disorders including congenital lymphatic anomalies, primary lymphoedema and obesity, while improved lymphat
Externí odkaz:
https://doaj.org/article/1ce6c97fa5a84fc2ac421a0adb73144d
Autor:
Ivy K N Chiang, Matthew S Graus, Nils Kirschnick, Tara Davidson, Winnie Luu, Richard Harwood, Keyi Jiang, Bitong Li, Yew Yan Wong, Mehdi Moustaqil, Emmanuelle Lesieur, Renae Skoczylas, Valerie Kouskoff, Jan Kazenwadel, Luis Arriola‐Martinez, Emma Sierecki, Yann Gambin, Kari Alitalo, Friedmann Kiefer, Natasha L Harvey, Mathias Francois
Refereed/Peer-reviewed Despite a growing catalog of secreted factors critical for lymphatic network assembly, little is known about the mechanisms that modulate the expression level of these molecular cues in blood vascular endothelial cells (BECs).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b743e950455b85e2c844ab2d4d566703
https://hdl.handle.net/11541.2/32559
https://hdl.handle.net/11541.2/32559
Autor:
Jan Kazenwadel, Parvathy Venugopal, Anna Oszmiana, John Toubia, Luis Arriola-Martinez, Virginia Panara, Sandra G. Piltz, Chris Brown, Wanshu Ma, Andreas W. Schreiber, Katarzyna Koltowska, Samir Taoudi, Paul Q. Thomas, Hamish S. Scott, Natasha L. Harvey
Refereed/Peer-reviewed Transcriptional enhancer elements are responsible for orchestrating the temporal and spatial control over gene expression that is crucial for programming cell identity during development. Here we describe a novel enhancer eleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350e247748b9d07be7b8263cc0bfd4cf
https://hdl.handle.net/11541.2/32594
https://hdl.handle.net/11541.2/32594
Autor:
Christopher J.H. Porter, Kian Liun Phang, Alina Lam, Vilena De Melo Ferreira, Gracia Gracia, Luojuan Hu, Hannah Chu, Tim Quach, Jamie S. Simpson, Alistair B.J. Escott, Anubhav Srivastava, Gabriela Segal, Jiwon Hong, Dovile Anderson, Sonya Agarwal, Darren J. Creek, Enyuan Cao, Natasha L. Harvey, Natalie L. Trevaskis, Anthony R. J. Phillips, John A. Windsor, Matthew J. Watt, Cameron J. Nowell
Publikováno v:
Nature Metabolism. 3:1175-1188
Refereed/Peer-reviewed Visceral adipose tissue (VAT) encases mesenteric lymphatic vessels and lymph nodes through which lymph is transported from the intestine and mesentery. Whether mesenteric lymphatics contribute to adipose tissue inflammation and