Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Natasha Kazdhan"'
Autor:
Guido Kroemer, AJ Robert McGray, Brian D Lichty, Byram W Bridle, Samuel T Workenhe, Jonathan G Pol, Yonghong Wan, Matthew J Atherton, Kyle B Stephenson, Natasha Kazdhan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Despite a sizeable body of research, the efficacy of therapeutic cancer vaccines remains limited when applied as sole agents. By using a prime:boost approach involving two viral cancer vaccines, we were able to generate large tumor-specific CD8+ T-ce
Externí odkaz:
https://doaj.org/article/745a8aaa49a74933957a9c308438cb2f
Autor:
Aj Robert McGray, Matthew J. Atherton, Guido Kroemer, Yonghong Wan, Byram W. Bridle, Kyle B Stephenson, Brian D. Lichty, Natasha Kazdhan, Samuel T Workenhe, Jonathan Pol
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer, 2020, 8 (2), pp.e000981. ⟨10.1136/jitc-2020-000981⟩
Journal for Immunotherapy of Cancer, BMJ Publishing Group 2020, 8 (2), pp.e000981. ⟨10.1136/jitc-2020-000981⟩
Journal for Immunotherapy of Cancer, 2020, 8 (2), pp.e000981. ⟨10.1136/jitc-2020-000981⟩
Journal for Immunotherapy of Cancer, BMJ Publishing Group 2020, 8 (2), pp.e000981. ⟨10.1136/jitc-2020-000981⟩
Despite a sizeable body of research, the efficacy of therapeutic cancer vaccines remains limited when applied as sole agents. By using a prime:boost approach involving two viral cancer vaccines, we were able to generate large tumor-specific CD8+ T-ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67482b31633bd93ce841c10d9e6d39dc
https://doi.org/10.1136/jitc-2020-000981
https://doi.org/10.1136/jitc-2020-000981
Autor:
Eleanor Pullenayegum, Brian D. Lichty, Sandeep T. Koshy, Kyle B Stephenson, Yonghong Wan, Jeanette E. Boudreau, Jérôme Brunellière, Natasha Kazdhan, Byram W. Bridle, Jonathan L. Bramson
Publikováno v:
Molecular Therapy. 18(8):1430-1439
Oncolytic viruses (OVs) are highly immunogenic and this limits their use in immune-competent hosts. Although immunosuppression may improve viral oncolysis, this gain is likely achieved at the cost of antitumoral immunity. We have developed a strategy
Publikováno v:
Journal of Virological Methods. 153:276-279
A method is described for the use of a G-deleted, conditionally replicating version of vesicular stomatitis virus (VSV) to measure alterations to the innate anti-viral state of cells in vitro. By co-transfecting a gene of interest with an expression
Autor:
Jonathan L. Bramson, Natasha Kazdhan, Liang Zhang, Stephen Hanson, Julien Rességuier, Brian D. Lichty, David F. Stojdl, Lan Chen, Yonghong Wan, Jonathan Pol, Kyle B Stephenson, Byram W. Bridle
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 22(2)
The rhabdovirus Maraba has recently been characterized as a potent oncolytic virus. In the present study, we engineered an attenuated Maraba strain, defined as MG1, to express a melanoma-associated tumor antigen. Its ability to mount an antitumor imm