Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Natasha J. Caplen"'
Autor:
Patrick J. Grohar, Suntae Kim, Guillermo O. Rangel Rivera, Nirmalya Sen, Sara Haddock, Matt L. Harlow, Nichole K. Maloney, Jack Zhu, Maura O’Neill, Tamara L. Jones, Konrad Huppi, Magdalena Grandin, Kristen Gehlhaus, Carleen A. Klumpp-Thomas, Eugen Buehler, Lee J. Helman, Scott E. Martin, Natasha J. Caplen
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 598-610 (2016)
Ewing sarcoma cells depend on the EWS-FLI1 fusion transcription factor for cell survival. Using an assay of EWS-FLI1 activity and genome-wide RNAi screening, we have identified proteins required for the processing of the EWS-FLI1 pre-mRNA. We show th
Externí odkaz:
https://doaj.org/article/e0445cac1cc6472395667e9686543812
Autor:
Roshan L. Shrestha, Vinutha Balachandra, Jee Hun Kim, Austin Rossi, Pranathi Vadlamani, Subhash Chandra Sethi, Laurent Ozbun, Shinjen Lin, Ken Chin-Chien Cheng, Raj Chari, Tatiana S. Karpova, Gianluca Pegoraro, Daniel R. Foltz, Natasha J. Caplen, Munira A. Basrai
Publikováno v:
Journal of Cell Science. 136
Restricting the localization of the evolutionarily conserved centromeric histone H3 variant CENP-A to centromeres prevents chromosomal instability (CIN). The mislocalization of CENP-A to non-centromeric regions contributes to CIN in yeasts, flies and
Autor:
Patrick J. Grohar, Lee J. Helman, Natasha J. Caplen, Scott E. Martin, Susan M. Kitchen-Goosen, Carleen A. Klumpp-Thomas, Marie Adams, Sergey Dikalov, Ian Beddows, Zachary B. Madaj, Brandon M. Oswald, Elissa A. Boguslawski, Joel H. Everett, Guillermo Flores
Laboratory values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501062fa1daa46709fce14f79900fb92
https://doi.org/10.1158/1535-7163.22518997.v1
https://doi.org/10.1158/1535-7163.22518997.v1
Autor:
Anita Tandle, Kevin Camphausen, Natasha J. Caplen, Riccardo Colombo, Uma Shankavaram, Orieta Celiku, Shuping Zhao, Ryan Hanson, Tamalee Kramp, Uday Bhanu Maachani
Supplementary Figure 1: Inhibition of MPS1 activity compromises the viability of GBM tumor cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3853aeff9f7b2a040b373b489a0bca
https://doi.org/10.1158/1541-7786.22513840
https://doi.org/10.1158/1541-7786.22513840
Autor:
Anita Tandle, Kevin Camphausen, Natasha J. Caplen, Riccardo Colombo, Uma Shankavaram, Orieta Celiku, Shuping Zhao, Ryan Hanson, Tamalee Kramp, Uday Bhanu Maachani
Supplementary Figure 6. Kaplan-Meier curve analysis examining MPS1 expression (red- high expression, black- low expression) and overall survival association in 1115 breast (A) and 1405 lung (B) cancer patients using univariate analysis using KM-Plott
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2737d6c8655da9aa2874b5b9527549e7
https://doi.org/10.1158/1541-7786.22513825
https://doi.org/10.1158/1541-7786.22513825
Autor:
Anita Tandle, Kevin Camphausen, Natasha J. Caplen, Riccardo Colombo, Uma Shankavaram, Orieta Celiku, Shuping Zhao, Ryan Hanson, Tamalee Kramp, Uday Bhanu Maachani
Supplementary Figure 3. Western blot analysis of pDNAPK and DNAPK from 2.5 uM NMS-P715 treated and irradiated (4 Gy) U251 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e007eee0a4e1cba5f77ca7a1a9dd6c
https://doi.org/10.1158/1541-7786.22513834
https://doi.org/10.1158/1541-7786.22513834
Autor:
Anita Tandle, Kevin Camphausen, Natasha J. Caplen, Riccardo Colombo, Uma Shankavaram, Orieta Celiku, Shuping Zhao, Ryan Hanson, Tamalee Kramp, Uday Bhanu Maachani
Supplementary Figure 2. Molecular profiling reveals changes in genes associated with DNA replication, recombination and repair.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101a7071a4ec8b8e3ba3ace72e9dc081
https://doi.org/10.1158/1541-7786.22513837
https://doi.org/10.1158/1541-7786.22513837
Autor:
Anita Tandle, Kevin Camphausen, Natasha J. Caplen, Riccardo Colombo, Uma Shankavaram, Orieta Celiku, Shuping Zhao, Ryan Hanson, Tamalee Kramp, Uday Bhanu Maachani
Supplementary Figure 5. To assay nonhomologous end joining (NHEJ), U251 DR-GFP cells were transfected with pCBAScel vector and harvested at 48 hours after indicated treatments. Genomic DNA was harvested for PCR amplification using DR-GFP primers, fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ca9c0cd8de805505fd30a48b381fe0
https://doi.org/10.1158/1541-7786.22513828
https://doi.org/10.1158/1541-7786.22513828
Autor:
Anita Tandle, Kevin Camphausen, Natasha J. Caplen, Riccardo Colombo, Uma Shankavaram, Orieta Celiku, Shuping Zhao, Ryan Hanson, Tamalee Kramp, Uday Bhanu Maachani
Supplementary Figure 4. To assay homologous recombination (HR), U251 DR-GFP cells were transfected with pCBAScel vector and harvested at 48 hours after indicated treatments. GFP+ve cells representing HR repair events were determined by flow cytometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e93da261b5769a26c407cd3ad37dac
https://doi.org/10.1158/1541-7786.22513831.v1
https://doi.org/10.1158/1541-7786.22513831.v1