Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Natasha H. Banke"'
Multiphasic triacylglycerol dynamics in the intact heart during acute in vivo overexpression of CD36
Autor:
Andrew N. Carley, Jian Bi, Xuerong Wang, Natasha H. Banke, Jason R.B. Dyck, J. Michael O'Donnell, E. Douglas Lewandowski
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 1, Pp 97-106 (2013)
Cardiac triacylglycerol (TAG) stores buffer the intracellular availability of long chain fatty acid (LCFA) that act as nuclear receptor ligands, substrate for lipotoxic derivatives, and high energy-yield fuel. The kinetic characteristics of TAG turno
Externí odkaz:
https://doaj.org/article/93403b84088b4901848010bd0bf033b2
Autor:
Chehade N. Karam, E. Douglas Lewandowski, R. John Solaro, Marcus Henze, Natasha H. Banke, Chad M. Warren
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 312:H681-H690
Although alterations in fatty acid (FA) metabolism have been shown to have a negative impact on contractility of the hypertrophied heart, the targets of action remain elusive. In this study we compared the function of skinned fiber bundles from trans
Autor:
Daniel P. Kelly, Adam R. Wende, J. Michael O'Donnell, Teresa C. Leone, E. Douglas Lewandowski, Natasha H. Banke, E. Dale Abel
Publikováno v:
Circulation Research. 107:233-241
Rationale : Long chain fatty acids (LCFAs) are the preferred substrate for energy provision in hearts. However, the contribution of endogenous triacylglyceride (TAG) turnover to LCFA oxidation and the overall dependence of mitochondrial oxidation on
Diabetic hearts are subject to more extensive ischemia/reperfusion (ISC/REP) damage. This study examined the efficiency of citric acid cycle (CAC) flux and the transfer of cytosolic reducing equivalents into the mitochondria for oxidative support of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d8c8d8466e08fb50c7eca0d6f7e588
https://europepmc.org/articles/PMC4302014/
https://europepmc.org/articles/PMC4302014/
Multiphasic triacylglycerol dynamics in the intact heart during acute in vivo overexpression of CD36
Autor:
Jason R.B. Dyck, Natasha H. Banke, Xuerong Wang, J. Michael O'Donnell, E. Douglas Lewandowski, Jian Bi, Andrew N Carley
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 1, Pp 97-106 (2013)
Cardiac triacylglycerol (TAG) stores buffer the intracellular availability of long chain fatty acid (LCFA) that act as nuclear receptor ligands, substrate for lipotoxic derivatives, and high energy-yield fuel. The kinetic characteristics of TAG turno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484db2a74c02f36eae851b1f94399daf
https://europepmc.org/articles/PMC3520544/
https://europepmc.org/articles/PMC3520544/
Autor:
Gary D. Lopaschuk, Alda Huqi, E. Douglas Lewandowski, Susan K. Fischer, Lori A. Walker, Xuerong Wang, J. Michael O'Donnell, Natasha H. Banke, Matthew Fasano
Publikováno v:
Circulation research. 112(1)
Rationale: Muscle carnitine palmitoyltransferase I is predominant in the heart, but the liver isoform (liver carnitine palmitoyltransferase I [L-CPT1]) is elevated in hearts with low long chain fatty acid oxidation, such as fetal and hypertrophied he
Autor:
E. Douglas Lewandowski, Mariana S. De Lorenzo, Sunil Dhar, Lin Yan, Heather Reinhardt, Stephen F. Vatner, Kayla M Pound, Natasha H. Banke
Human studies indicate augmented myocardial lipid metabolism in females, and that sex and obesity interact to predict myocardial fatty acid oxidation and storage. Altered lipid dynamics precede cardiomyopathies, and many studies now address high fat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8c9825eaa17eddd304ef928013aae0
https://europepmc.org/articles/PMC3294178/
https://europepmc.org/articles/PMC3294178/
Publikováno v:
Circulation. Cardiovascular imaging. 3(6)
Background— Myocardial lipid accumulation precedes some cardiomyopathies, but little is known of concurrent effects on ventricular mechanics. We tested the hypothesis that intramyocardial lipid accumulation during a short-term, high-fat diet (HFD)
Publikováno v:
Circulation. 118
Peroxisome proliferator-activated receptor alpha (PPARα) is a nuclear receptor involved in regulating fatty acid utilization and is implicated in the pathogenesis of diabetic cardiomyopathy. However, the involvement of PPARα in the specific utiliza
Publikováno v:
Journal of Molecular and Cellular Cardiology. 42:S63