Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Natasha Chandiramani"'
1
Akademický článek
Molecular basis for vulnerability to mitochondrial and oxidative stress in a neuroendocrine CRI-G1 cell line.
Autor: Natasha Chandiramani, Xianhong Wang, Marta Margeta
Publikováno v: PLoS ONE, Vol 6, Iss 1, p e14485 (2011)
Many age-associated disorders (including diabetes, cancer, and neurodegenerative diseases) are linked to mitochondrial dysfunction, which leads to impaired cellular bioenergetics and increased oxidative stress. However, it is not known what genetic a
Externí odkaz: https://doaj.org/article/070443e31a6a4b32b4286e25896b9492
Zobrazit plný text záznamu
3
Data from Amphiregulin Is a Critical Downstream Effector of Estrogen Signaling in ERα-Positive Breast Cancer
Autor: Paraic A. Kenny, Maryia Barnett, Evelyn Aranda, Hui Liu, Natasha Chandiramani, Kristopher A. Lofgren, Edmund C. Jenkins, Esther A. Peterson
Estrogen stimulation promotes epithelial cell proliferation in estrogen receptor (ERα)-positive breast cancer. Many ERα target genes have been enumerated, but the identities of the key effectors mediating the estrogen signal remain obscure. During
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5733b2c648d7903df14893d0e943c957
https://doi.org/10.1158/0008-5472.c.6508142
Zobrazit plný text záznamu
4
Abstract P1-08-02: Mutant GATA3 actively promotes the growth of normal and malignant mammary cells
Autor: Esther A. Peterson, Paraic A. Kenny, Natasha Chandiramani
Publikováno v: Cancer Research. 77:P1-08
GATA3 is a transcription factor expressed in luminal breast epithelial cells and is required for mammary gland development. Analysis of TCGA data reveals that somatic heterozygous mutations in GATA3 occur in up to 15% of estrogen receptor positive br
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9fbede99f4e0c2b47ce687dd92d5548f
https://doi.org/10.1158/1538-7445.sabcs16-p1-08-02
Zobrazit plný text záznamu
6
Abstract P5-07-02: Mutant GATA3 causes precocious lobuloalveolar development in the mouse mammary gland and is associated with more aggressive human breast cancer
Autor: Paraic A. Kenny, Esther A. Peterson, Natasha Chandiramani
Publikováno v: Cancer Research. 73:P5-07
GATA3 is an essential mediator of mammary gland development and is expressed at high levels in Estrogen Receptor positive tumors. This gene has recently emerged as one of the most frequently mutated genes in Estrogen Receptor positive breast cancer.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a947cdbb7779223e1826d35ddc9159d
https://doi.org/10.1158/0008-5472.sabcs13-p5-07-02
Zobrazit plný text záznamu
7
Amphiregulin is a critical downstream effector of estrogen signaling in ERα-positive breast cancer
Autor: Kristopher A. Lofgren, Esther A. Peterson, Edmund C. Jenkins, Paraic A. Kenny, Hui Liu, Natasha Chandiramani, Maryia Barnett, Evelyn Aranda
Estrogen stimulation promotes epithelial cell proliferation in estrogen receptor (ERα)-positive breast cancer. Many ERα target genes have been enumerated, but the identities of the key effectors mediating the estrogen signal remain obscure. During
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd7c357e5a4db1c7e380027f4a16049
https://europepmc.org/articles/PMC4651747/
Zobrazit plný text záznamu
8
Abstract P2-04-06: Transgenic expression of a breast-cancer specific GATA3 mutant leads to mammary hyperplasia
Autor: Natasha Chandiramani, Paraic A. Kenny
Publikováno v: Cancer Research. 72:P2-04
GATA3 is expressed in normal luminal breast epithelial cells and is a key transcription factor in mammary gland development. In human breast tumors, high GATA3 protein levels are associated with estrogen receptor (ER) positivity and low grade. Recent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56aad03478e296b24b9446f76debb619
https://doi.org/10.1158/0008-5472.sabcs12-p2-04-06
Zobrazit plný text záznamu
9
Abstract 1991: Mutant GATA3 actively promotes the growth of normal and malignant mammary cells
Autor: Natasha Chandiramani, Esther Peterson, Paraic A. Kenny
Publikováno v: Cancer Research. 76:1991-1991
GATA3 is a transcription factor expressed in luminal breast epithelial cells and is required for mammary gland development. Analysis of TCGA data reveals that somatic heterozygous mutations in GATA3 occur in up to 15% of estrogen receptor positive br
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b8c06a6ed0148a00cd1aaa995c1c9a2
https://doi.org/10.1158/1538-7445.am2016-1991
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje