Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Natasha C. Brooks"'
Autor:
Natasha C. Brooks, Alexandra H. Marshall, Nour Qa’aty, Yaeko Hiyama, Darren Boehning, Marc G. Jeschke
Publikováno v:
Molecular Medicine, Vol 19, Iss 1, Pp 72-78 (2013)
Abstract The first 24 h following burn injury is known as the ebb phase and is characterized by a depressed metabolic rate. While the postburn ebb phase has been well described, the molecular mechanisms underlying this response are poorly understood.
Externí odkaz:
https://doaj.org/article/dc9698236d0844f1b8a1d5d5736ed4a4
Autor:
Juquan Song, Xiao-jun Zhang, Darren Boehning, Natasha C. Brooks, David N. Herndon, Marc G. Jeschke
Publikováno v:
International Journal of Biological Sciences, Vol 8, Iss 2, Pp 265-271 (2012)
Severe burn-induced liver damage and dysfunction is associated with endoplasmic reticulum (ER) stress. ER stress has been shown to regulate global protein synthesis. In the current study, we induced ER stress in vitro and estimated the effect of ER s
Externí odkaz:
https://doaj.org/article/780b6793ef2a48eb84b17ad73ef73826
Autor:
Gabriel A. Mecott, Jong O. Lee, Marc G. Jeschke, Gabriela A. Kulp, Manuel Diblidox-Gonzales, Haidy G. Rivero, Natasha C. Brooks, Hal K. Hawkins, David N. Herndon, Robert Kraft
Publikováno v:
Burns. 37:82-85
Few publications recognize acute pancreatitis as a complication after large burns, consequently the incidence and outcome acute pancreatitis after burn in children is not well defined. The aim of this study was to determine the incidence, morbidity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c4e4f3083fce38727619bd813c67d7
https://doi.org/10.1016/j.burns.2010.07.015
https://doi.org/10.1016/j.burns.2010.07.015
Autor:
Alexandra H. Marshall, Marc G. Jeschke, Natasha C. Brooks, Nour Qa'aty, Darren Boehning, Yaeko Hiyama
The first 24 h following burn injury is known as the ebb phase and is characterized by a depressed metabolic rate. While the postburn ebb phase has been well described, the molecular mechanisms underlying this response are poorly understood. The endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ec21fbb4e83ab55b74b85e8d31b2b5
https://europepmc.org/articles/PMC3667210/
https://europepmc.org/articles/PMC3667210/
Autor:
Marc G. Jeschke, Yaeko Hiyama, Natasha C. Brooks, Alexandra H. Marshall, Ahmed M. Al-Mousawi, Celeste C. Finnerty, Nour Qa'aty
The trauma of a severe burn injury induces a hypermetabolic response that increases morbidity and mortality. Previously, our group showed that insulin resistance after burn injury is associated with endoplasmic reticulum (ER) stress. Evidence suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e957694a662752ff00b2ef49e30bf3fc
https://europepmc.org/articles/PMC3552323/
https://europepmc.org/articles/PMC3552323/
Autor:
Celeste C. Finnerty, Yaeko Hiyama, Alexandra H. Smith, David N. Herndon, Marc G. Jeschke, Natasha C. Brooks, Darren Boehning
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a041afff07a490f93dadfcf195ee70ec
https://doi.org/10.1096/fasebj.26.1_supplement.758.7
https://doi.org/10.1096/fasebj.26.1_supplement.758.7
Autor:
Celeste C. Finnerty, Darren Boehning, Juquan Song, Robert Kraft, David N. Herndon, Marc G. Jeschke, Natasha C. Brooks
Severe burn injury is associated with induction of the hepatic endoplasmic reticulum (ER) stress response. ER stress leads to activation of c-Jun N-terminal kinase (JNK), suppression of insulin receptor signaling via phosphorylation of insulin recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67016a8daeafc8d89cf3f7e92f616705
https://europepmc.org/articles/PMC3388140/
https://europepmc.org/articles/PMC3388140/
Autor:
Ronald G. Tompkins, Darren Boehning, Juquan Song, Marc G. Jeschke, Robert Kraft, David N. Herndon, Celeste C. Finnerty, Natasha C. Brooks
Burn induces a hypermetabolic state characterized by alterations in protein metabolism, which is associated with increased morbidity and mortality. Eukaryotic elongation factor 2 (eEF2) plays a crucial role in regulating protein synthesis in many dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb985e473a67407588d9ff55812e3a6
https://europepmc.org/articles/PMC3580832/
https://europepmc.org/articles/PMC3580832/
Autor:
Natasha C. Brooks, Celeste C. Finnerty, Gerd G. Gauglitz, Darren Boehning, David N. Herndon, Juquan Song, Marc G. Jeschke, Robert A. Cox, Gabriela A. Kulp, Robert Kraft
Publikováno v:
Molecular medicine (Cambridge, Mass.). 17(5-6)
Burn injury causes hepatic dysfunction associated with endoplasmic reticulum (ER) stress and induction of the unfolded protein response (UPR). ER stress/UPR leads to hepatic apoptosis and activation of the Jun-N-terminal kinase (JNK) signaling pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c063ccf5261c7e77297bfb32b8921d
https://pubmed.ncbi.nlm.nih.gov/21267509
https://pubmed.ncbi.nlm.nih.gov/21267509
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae36efba6c58bcdb7b21dd6f882f3969
https://doi.org/10.1096/fasebj.24.1_supplement.485.1
https://doi.org/10.1096/fasebj.24.1_supplement.485.1