Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Natasha, Krishnadas"'
Autor:
Azadeh Feizpour, James David Doecke, Vincent Doré, Natasha Krishnadas, Kun Huang, Pierrick Bourgeat, Simon Matthew Laws, Christopher Fowler, Joanne Robertson, Lucy Mackintosh, Scott Ayton, Ralph Martins, Stephanie Ruth Rainey-Smith, Kevin Taddei, Larry Ward, Eddie Stage, Anthony Wilson Bannon, Colin Louis Masters, Jurgen Fripp, Victor Luis Villemagne, Christopher Cleon Rowe
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105405- (2024)
Summary: Background: Plasma phospho-tau 217 (pTau217) assays can accurately detect Alzheimer's disease (AD) pathology, but clinical application is limited by the need for specialised equipment. This study tests the performance of a plasma pTau217 ass
Externí odkaz:
https://doaj.org/article/5b388413e0784c49a4221b9a0b49897b
Autor:
Victor L. Villemagne, Antoine Leuzy, Sandra Sanabria Bohorquez, Santiago Bullich, Hitoshi Shimada, Christopher C. Rowe, Pierrick Bourgeat, Brian Lopresti, Kun Huang, Natasha Krishnadas, Jurgen Fripp, Yuhei Takado, Alexandra Gogola, Davneet Minhas, Robby Weimer, Makoto Higuchi, Andrew Stephens, Oskar Hansson, Vincent Doré, Alzheimer's Disease Neuroimaging Initiative and the AIBL research group
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 3, Pp n/a-n/a (2023)
Abstract INTRODUCTION Recently, an increasing number of tau tracers have become available. There is a need to standardize quantitative tau measures across tracers, supporting a universal scale. We developed several cortical tau masks and applied them
Externí odkaz:
https://doaj.org/article/e3a442eac9e64af3bc0f3fc0565a03c8
Autor:
Natasha Krishnadas, Vincent Doré, Colin Groot, Fiona Lamb, Pierrick Bourgeat, Samantha C. Burnham, Kun Huang, Anita M. Y. Goh, Colin L. Masters, Victor L. Villemagne, Christopher C. Rowe, for the AIBL research group
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Background Tau deposition in the mesial temporal lobe (MTL) in the absence of amyloid-β (Aβ−) occurs with aging. The tau PET tracer 18F-MK6240 has low non-specific background binding so is well suited to exploration of early-stage tau de
Externí odkaz:
https://doaj.org/article/29865099cabe401bb295621f4d6488e7
Autor:
Natasha Krishnadas, Vincent Doré, Joanne S. Robertson, Larry Ward, Christopher Fowler, Colin L. Masters, Pierrick Bourgeat, Jurgen Fripp, Victor L. Villemagne, Christopher C. Rowe
Publikováno v:
EBioMedicine, Vol 88, Iss , Pp 104450- (2023)
Summary: Background: Tau positron emission tomography (PET) imaging enables longitudinal observation of tau accumulation in Alzheimer's disease (AD). 18F-MK6240 is a high affinity tracer for the paired helical filaments of tau in AD, widely used in c
Externí odkaz:
https://doaj.org/article/7e21ddc3ac4d463bb3a3c525facb4ad9
Autor:
Bruce Taylor, Natasha Krishnadas
Publikováno v:
BMJ Neurology Open, Vol 3, Iss 1 (2021)
Introduction Anecdotally, the incidence of idiopathic intracranial hypertension (IIH) is increasing, linked to an increase in the obesity rate in Australian society. However, formal incidence and prevalence studies are rare. We therefore sought to de
Externí odkaz:
https://doaj.org/article/6471016bfef74aa0b5ae0999894ab60c
Autor:
Natasha Krishnadas
Publikováno v:
Journal of Alzheimer's Disease. 92:615-628
Background: Astrocyte reactivity is an early event along the Alzheimer’s disease (AD) continuum. Plasma glial fibrillary acidic protein (GFAP), posited to reflect astrocyte reactivity, is elevated across the AD continuum from preclinical to dementi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13d3dbe9e116bd465451eb6d3311d912
https://doi.org/10.3233/jad-220908
https://doi.org/10.3233/jad-220908
Autor:
Natasha Krishnadas, Vincent Doré, Fiona Lamb, Colin Groot, Paul McCrory, Rodney Guzman, Rachel Mulligan, Kun Huang, Meaghan O'Donnell, Jennie Ponsford, Malcolm Hopwood, Victor L. Villemagne, Christopher C. Rowe
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Introduction: It remains unclear if tau imaging may assist diagnosis of chronic traumatic encephalopathy (CTE). Flortaucipir PET has shown superior frontal with medial temporal tau binding consistent with the provisional neuropathological criteria fo
Externí odkaz:
https://doaj.org/article/12e41b2b82144180ad02dee6432fd152
Autor:
Victor L. Villemagne, Ryuichi Harada, Vincent Doré, Shozo Furumoto, Rachel Mulligan, Yukitsuka Kudo, Samantha Burnham, Natasha Krishnadas, Pierrick Bourgeat, Ying Xia, Simon Laws, Svetlana Bozinovski, Kun Huang, Milos D. Ikonomovic, Jürgen Fripp, Kazuhiko Yanai, Nobuyuki Okamura, Christopher C. Rowe
Publikováno v:
J Nucl Med
A neuroinflammatory reaction in Alzheimer disease (AD) brains involves reactive astrocytes that overexpress monoamine oxidase-B (MAO-B). (18)F-(S)-(2-methylpyrid-5-yl)-6-[(3-fluoro-2-hydroxy)propoxy]quinoline ((18)F-SMBT-1) is a novel (18)F PET trace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ea4d52f7a7376273a925257dbb0a60
https://doi.org/10.2967/jnumed.121.263255
https://doi.org/10.2967/jnumed.121.263255
Autor:
Victor L. Villemagne, Ryuichi Harada, Vincent Doré, Shozo Furumoto, Rachel Mulligan, Yukitsuka Kudo, Samantha Burnham, Natasha Krishnadas, Svetlana Bozinovski, Kun Huang, Brian J. Lopresti, Kazuhiko Yanai, Christopher C. Rowe, Nobuyuki Okamura
Publikováno v:
J Nucl Med
Reactive gliosis, characterized by reactive astrocytes and activated microglia, contributes greatly to neurodegeneration throughout the course of Alzheimer disease (AD). Reactive astrocytes overexpress monoamine oxidase B (MAO-B). We characterized th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d639c6ea3f8d92a6ee34a44fd0fa71c3
https://doi.org/10.2967/jnumed.121.263254
https://doi.org/10.2967/jnumed.121.263254
Autor:
Natasha Krishnadas
Publikováno v:
Journal of Neurotrauma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d02d8b9d5aca40b0a812d789dbb3c86
https://doi.org/10.1089/neu.2022.0172
https://doi.org/10.1089/neu.2022.0172