Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Natascia Ventura"'
Autor:
Leila Benayada, Federica Gubitosa, Daniele Fraternale, Silvia Carloni, Liana Cerioni, Giulia Matacchione, Fabiola Olivieri, Lucia Potenza, Roberta De Bellis, Laura Chiarantini, Carla Roselli, Laura Valentini, Pietro Gobbi, Walter Balduini, Noemi Pappagallo, Natascia Ventura, George E.N. Kass, Mariastella Colomba, Maria Cristina Albertini
Publikováno v:
Journal of Functional Foods, Vol 121, Iss , Pp 106420- (2024)
The anti-inflammatory activity of the “Mela Rosa Marchigiana” (MRM) pulp callus ethanol Extract (MRME) was tested in different cellular models including (i) LPS-treated RAW 264.7; (ii) HUVEC exposed to short-term high Glucose (HG, 45 mM) or norma
Externí odkaz:
https://doaj.org/article/6ca449023438497099508af62d450a1d
Autor:
Eugenia Piragine, Martina De Felice, Lorenzo Germelli, Vanessa Brinkmann, Lorenzo Flori, Claudia Martini, Vincenzo Calderone, Natascia Ventura, Eleonora Da Pozzo, Lara Testai
Publikováno v:
Experimental Gerontology, Vol 194, Iss , Pp 112495- (2024)
Aging is one of the main risk factors for neurodegenerative disorders, which represent a global burden on healthcare systems. Therefore, identifying new strategies to slow the progression of brain aging is a compelling challenge. In this article, we
Externí odkaz:
https://doaj.org/article/2aafe5b68c084df8b5bb4c954508caf7
Autor:
Federica Gubitosa, Leila Benayada, Daniele Fraternale, Roberta De Bellis, Silvia Carloni, Lucia Potenza, Laura Chiarantini, Andrea Gorassini, Giancarlo Verardo, Carla Roselli, Laura Valentini, Pietro Gobbi, Walter Balduini, Natascia Ventura, Francesca Giannaccini, George E.N. Kass, Mariastella Colomba, Maria Cristina Albertini
Publikováno v:
Journal of Functional Foods, Vol 114, Iss , Pp 106073- (2024)
The Mela Rosa Marchigiana (MRM) pulp callus, kept alive since 2017 by monthly sub-cultures, was investigated and morphologically described. In the present paper, the MRM callus ethanolic Extract (MRME) was prepared from one of the 2022 callus sub-cul
Externí odkaz:
https://doaj.org/article/96f37b480ce448a68a3c72749a35ed2f
Autor:
Alfonso Schiavi, Claudia Cirotti, Lora-Sophie Gerber, Giulia Di Lauro, Silvia Maglioni, Priscila Yumi Tanaka Shibao, Sabrina Montresor, Janine Kirstein, Patrick Petzsch, Karl Köhrer, Roel P. F. Schins, Tina Wahle, Daniela Barilà, Natascia Ventura
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-22 (2023)
Abstract Alzheimer’s disease is the most common age-associated neurodegenerative disorder and the most frequent form of dementia in our society. Aging is a complex biological process concurrently shaped by genetic, dietary and environmental factors
Externí odkaz:
https://doaj.org/article/b943984ede4d4379a2a87b1088dc502b
Autor:
Silvia Maglioni, Alfonso Schiavi, Marlen Melcher, Vanessa Brinkmann, Zhongrui Luo, Anna Laromaine, Nuno Raimundo, Joel N. Meyer, Felix Distelmaier, Natascia Ventura
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Mitochondrial deficiency causes rare incurable disorders. Here, the authors use C. elegans to study these diseases and find that the natural compound lutein prevents neurodevelopmental deficits, thus pointing to a possible therapeutic target for the
Externí odkaz:
https://doaj.org/article/58b5a0011c434f13b5493957dc295694
Autor:
Alfonso Schiavi, Eva Salveridou, Vanessa Brinkmann, Anjumara Shaik, Ralph Menzel, Sumana Kalyanasundaram, Ståle Nygård, Hilde Nilsen, Natascia Ventura
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106448- (2023)
Summary: Excessive iron accumulation or deficiency leads to a variety of pathologies in humans and developmental arrest in the nematode Caenorhabditis elegans. Instead, sub-lethal iron depletion extends C. elegans lifespan. Hypoxia preconditioning pr
Externí odkaz:
https://doaj.org/article/718e9a6fdb4d42a78172e8de69e26027
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/cfaa2be9f7f24f909dcd92879574d74b
Autor:
Onofrio Valente, Jochen Dobner, Haribaskar Ramachandran, Barbara Hildebrandt, Felix Distelmaier, Natascia Ventura, Andrea Rossi
Publikováno v:
Stem Cell Research, Vol 65, Iss , Pp 102971- (2022)
Human dermal fibroblasts from a Leigh Syndrome (LS) patient harboring the heterozygous NDUFS1 R557X/D618N compound mutation were reprogrammed to generate integration-free induced pluripotent stem cells (iPSCs). The full characterization of IUFi002-A-
Externí odkaz:
https://doaj.org/article/96b7f89aed474bd8a205a7951aff6680
Autor:
Alfonso Schiavi, Alessandra Runci, Teresa Maiorino, Francesco Davide Naso, Marta Barenys, Ellen Fritsche, Flavie Strappazzon, Natascia Ventura
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Severe oxygen and iron deficiencies have evolutionarily conserved detrimental effects, leading to pathologies in mammals and developmental arrest as well as neuromuscular degeneration in the nematode Caenorhabditis elegans. Yet, similar to the benefi
Externí odkaz:
https://doaj.org/article/c752c67eeb67431790c27c68db397cc6
Autor:
Carmen Martínez-Fernández, Milana Bergamino, Alfonso Schiavi, David Brena, Natascia Ventura, Sebastian Honnen, Alberto Villanueva, Ernest Nadal, Julián Cerón
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 3 (2022)
Cisplatin is the most common drug in first-line chemotherapy against solid tumors. We and others have previously used the nematode Caenorhabditis elegans to identify genetic factors influencing the sensitivity and resistance to cisplatin. In this stu
Externí odkaz:
https://doaj.org/article/cdcb1c8b76c94909a5a92b8767d40b32