Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Natascia Mennini"'
Autor:
Francesca Maestrelli, Marzia Cirri, Natascia Mennini, Silvia Fiani, Beatrice Stoppacciaro, Paola Mura
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 633 (2024)
New oral tablets of nebivolol have been developed aiming to improve, by cyclodextrin (CD) complexation, its low solubility/dissolution properties—the main reason behind its poor/variable oral bioavailability. Phase-solubility studies, performed usi
Externí odkaz:
https://doaj.org/article/e417fe18ca5b48a58231e1c77318c1e1
Autor:
Eugenia Romano, Claudio Campagnuolo, Roberta Palladino, Giulia Schiavo, Barbara Maglione, Cristina Luceri, Natascia Mennini
Publikováno v:
Bioengineering, Vol 10, Iss 9, p 1022 (2023)
Chronic wound is characterized by slow healing time, persistence, and abnormal healing progress. Therefore, serious complications can lead at worst to the tissue removal. In this scenario, there is an urgent need for an ideal dressing capable of high
Externí odkaz:
https://doaj.org/article/7f5cc1a0c7df459390e830dfb7f5d07a
Autor:
Giulia Nerli, Lídia M. D. Gonçalves, Marzia Cirri, António J. Almeida, Francesca Maestrelli, Natascia Mennini, Paola A. Mura
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1305 (2023)
There is a serious need of pediatric drug formulations, whose lack causes the frequent use of extemporaneous preparations obtained from adult dosage forms, with consequent safety and quality risks. Oral solutions are the best choice for pediatric pat
Externí odkaz:
https://doaj.org/article/85b3c7ca18284c59ab484ea8e044bba2
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2567 (2022)
Nanogels combine the properties of hydrogels and nanocarrier systems, resulting in very effective drug delivery systems, including for cutaneous applications. Cyclodextrins (CDs) have been utilised to enhance the nanogels’ loading ability towards p
Externí odkaz:
https://doaj.org/article/47bd99645ba643b6b4a30f32e63ad74d
Publikováno v:
Marine Drugs, Vol 20, Iss 5, p 335 (2022)
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after cellulose, is the second biopolymer most abundant in nature, being the primary component of the exoskeleton of crustaceans and insects. Since joining the p
Externí odkaz:
https://doaj.org/article/5c887f89978f45aca8b4c25705d36421
Autor:
Daniela Catarzi, Flavia Varano, Erica Vigiani, Sara Calenda, Fabrizio Melani, Katia Varani, Fabrizio Vincenzi, Silvia Pasquini, Natascia Mennini, Giulia Nerli, Diego Dal Ben, Rosaria Volpini, Vittoria Colotta
Publikováno v:
Pharmaceuticals, Vol 15, Iss 4, p 478 (2022)
A new set of amino-3,5-dicyanopyridines was synthesized and biologically evaluated at the adenosine receptors (ARs). This chemical class is particularly versatile, as small structural modifications can influence not only affinity and selectivity, but
Externí odkaz:
https://doaj.org/article/2d4d17b2c4234db89836b4d36ba4b954
Autor:
Marzia Cirri, Lavinia Maestrini, Francesca Maestrelli, Natascia Mennini, Paola Mura, Carla Ghelardini, Lorenzo Di Cesare Mannelli
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1910-1921 (2018)
The hydrochlorothiazide (HCT) low solubility and permeability give rise to limited and variable bioavailability; its low stability makes it difficult to develop stable aqueous liquid formulations; its low dose makes the achievement of a homogeneous d
Externí odkaz:
https://doaj.org/article/b3cef52e65084eed9725b8d03ede50e8
Autor:
Marzia Cirri, Natascia Mennini, Giulia Nerli, Jessica Rubia, Enrico Casalone, Fabrizio Melani, Francesca Maestrelli, Paola Mura
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1923 (2021)
Cefixime (CEF) is a cephalosporin included in the WHO Model List of Essential Medicines for Children. Liquid formulations are considered the best choice for pediatric use, due to their great ease of administration and dose-adaptability. Owing to its
Externí odkaz:
https://doaj.org/article/8ff4b916504049389c223a66506e05f6
Autor:
Marzia Cirri, Francesca Maestrelli, Giulia Nerli, Natascia Mennini, Mario D’Ambrosio, Cristina Luceri, Paola Angela Mura
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 969 (2021)
A thermosensitive, mucoadhesive in-situ gel for clonazepam (CLZ) intranasal delivery was developed, which aimed to achieve prolonged in-situ residence and controlled drug release, overcoming problems associated with its oral or parenteral administrat
Externí odkaz:
https://doaj.org/article/9d067e48e701435bb9a67ca219253f79
Autor:
Paola Mura, Francesca Maestrelli, Marzia Cirri, Giulia Nerli, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Natascia Mennini
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 872 (2021)
This work was aimed at enhancing butamben (BTB) anesthetic efficacy by the “drug-in cyclodextrin (CD)-in deformable liposomes” strategy. In the study, phase-solubility studies with natural (α-, β-, γ-) and derivative (hydroxypropyl-α-and β-,
Externí odkaz:
https://doaj.org/article/a200ae2958a04c62b25aa54a31b77b1c