Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nataschja I Ho"'
Autor:
Harry Dolstra, Gosse J Adema, Nataschja I Ho, Lisa G M Huis in 't Veld, Jesper van Eck van der Sluijs, Branco M H Heuts, Maaike W G Looman, Esther D Kers-Rebel, Koen van den Dries, Joost H A Martens, Willemijn Hobo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background Adjuvants are key for effective vaccination against cancer and chronic infectious diseases. Saponin-based adjuvants (SBAs) are unique among adjuvants in their ability to induce robust cell-mediated immune responses in addition to antibody
Externí odkaz:
https://doaj.org/article/c01dcb8743c64477b7c1e9befc909182
Autor:
Ingeborg Streng-Ouwehand, Nataschja I Ho, Manja Litjens, Hakan Kalay, Martine Annemarie Boks, Lenneke AM Cornelissen, Satwinder Kaur Singh, Eirikur Saeland, Juan J Garcia-Vallejo, Ferry A Ossendorp, Wendy WJ Unger, Yvette van Kooyk
Publikováno v:
eLife, Vol 5 (2016)
Antigen uptake by dendritic cells and intracellular routing of antigens to specific compartments is regulated by C-type lectin receptors that recognize glycan structures. We show that the modification of Ovalbumin (OVA) with the glycan-structure Lewi
Externí odkaz:
https://doaj.org/article/cc9b1971689946e283d4223a0cc25784
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Over the last decades, vaccine development has advanced significantly in pursuing higher safety with less side effects. However, this is often accompanied by a reduction in vaccine immunogenicity and an increased dependency on adjuvants to enhance va
Externí odkaz:
https://doaj.org/article/f5e78b49a87548288b6c3f2e24b5487b
Autor:
Lisa G M, Huis In 't Veld, Nataschja I, Ho, Melisssa, Wassink, Martijn H, den Brok, Gosse J, Adema
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(5)
Saponin-based adjuvants (SBAs) are promising new adjuvants that stand out as they not only enforce CD4 + T cell-mediated immunity and antibody responses, but also induce an unprecedented level of antigen cross-presentation by dendritic cells (DC) and
Autor:
Erik Bos, Martijn Verdoes, Ferry Ossendorp, Nataschja I Ho, Juan J. Garcia-Vallejo, Yvette van Kooyk, Abraham J. Koster, Marcel Camps
Publikováno v:
Immunology, 164(3), 494-506. WILEY
Immunology, 164, 494-506
Ho, N I, Camps, M G, Garcia-Vallejo, J J, Bos, E, Koster, A J, Verdoes, M, van Kooyk, Y & Ossendorp, F 2021, ' Distinct antigen uptake receptors route to the same storage compartments for cross-presentation in dendritic cells ', Immunology, vol. 164, no. 3, pp. 494-506 . https://doi.org/10.1111/imm.13382
Immunology
Immunology, 164, 3, pp. 494-506
Immunology, 164(3), 494-506. Wiley-Blackwell
Immunology, 164, 494-506
Ho, N I, Camps, M G, Garcia-Vallejo, J J, Bos, E, Koster, A J, Verdoes, M, van Kooyk, Y & Ossendorp, F 2021, ' Distinct antigen uptake receptors route to the same storage compartments for cross-presentation in dendritic cells ', Immunology, vol. 164, no. 3, pp. 494-506 . https://doi.org/10.1111/imm.13382
Immunology
Immunology, 164, 3, pp. 494-506
Immunology, 164(3), 494-506. Wiley-Blackwell
Contains fulltext : 244589.pdf (Publisher’s version ) (Open Access) An exclusive feature of dendritic cells (DCs) is their capacity to present exogenous antigens by MHC class I molecules, called cross-presentation. Here, we show that protein antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea542ea0192e15db7933c4d502ccb41
http://hdl.handle.net/1887/3261039
http://hdl.handle.net/1887/3261039
Autor:
Els M. E. Verdegaal, Nataschja I Ho, Geoffroy P.P. Gential, Ferry Ossendorp, Marten Visser, Wim Jiskoot, Thomas C. van den Ende, Dmitri V. Filippov, Gijsbert A. van der Marel, Sjoerd H. van der Burg, Nico J. Meeuwenoord, Herman S. Overkleeft, Jeroen D. C. Codée, A. Rob P. M. Valentijn, Jeroen Heuts, Michel J. van de Graaff
Publikováno v:
ChemBioChem, 22(7), 1215-1222. WILEY-V C H VERLAG GMBH
ChemBioChem, 22(7), 1215-1222
Chembiochem
ChemBioChem
ChemBioChem, 22(7), 1215-1222
Chembiochem
ChemBioChem
Synthetic vaccines, based on antigenic peptides that comprise MHC−I and MHC‐II T‐cell epitopes expressed by tumors, show great promise for the immunotherapy of cancer. For optimal immunogenicity, the synthetic peptides (SPs) should be adjuvante
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95fd1b32d8a40b85cb25522a547c5f6
http://hdl.handle.net/1887/3182822
http://hdl.handle.net/1887/3182822
Publikováno v:
European Journal of Immunology
European Journal of Immunology, 51(4), 835-847. WILEY
Eur J Immunology
European Journal of Immunology, 51, 4, pp. 835-847
European Journal of Immunology, 51, 835-847
European Journal of Immunology, 51(4), 835-847. WILEY
Eur J Immunology
European Journal of Immunology, 51, 4, pp. 835-847
European Journal of Immunology, 51, 835-847
Autophagy has been reported to be involved in supporting antigen cross‐presentation by dendritic cells (DCs). We have shown that DCs have the ability to store antigen for a prolonged time in endolysosomal compartments and thereby sustain MHCI antig
Autor:
Edwin F. E. de Haas, J. Sjef Verbeek, Ferry Ossendorp, Leendert A. Trouw, Nataschja I Ho, Marcel Camps
Publikováno v:
Journal of Immunology, 198(11), 4235-4243
Dendritic cells (DCs) are specialized in Ag engulfment via a wide variety of uptake receptors on their cell surface. In the present study we investigated Ag uptake and presentation of in vivo–formed Ag–Ab complexes by i.v. injecting mice with Ag-
Publikováno v:
European Journal of Immunology, 48(7), 1164-1173
European Journal of Immunology
European Journal of Immunology
An exclusive feature of dendritic cells (DCs) is their ability to cross‐present exogenous antigens in MHC class I molecules. We analyzed the fate of protein antigen in antigen presenting cell (APC) subsets after uptake of naturally formed antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34319252c6681df3d76d0935aba7878
http://hdl.handle.net/1887/86720
http://hdl.handle.net/1887/86720
Autor:
Gijs A. van der Marel, Dmitri V. Filippov, Geoffroy P.P. Gential, Herman S. Overkleeft, Ferry Ossendorp, Nico J. Meeuwenoord, Fabrizio Chiodo, Nataschja I Ho
Publikováno v:
Bioorganic and Medicinal Chemistry Letters, 26(15), 3641-3645
Chirally pure R- and S-epimers of TLR2 ligand Pam3CysSK4 were prepared and separately conjugated to an OVA model epitope, in which lysine was replaced by azidonorleucine. The azide function in the conjugate permitted labelling with different fluoroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c178ab0602518c433eb46fdc5846366a
https://hdl.handle.net/1887/112801
https://hdl.handle.net/1887/112801