Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Natascha van Lieshout"'
Autor:
Hongbo Li, Matthijs Brouwer, Elena Del Pup, Natascha van Lieshout, Richard Finkers, Christian W. B. Bachem, Richard G. F. Visser
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-24 (2024)
Abstract Background Tuber starch and steroidal glycoalkaloid (SGA)-related traits have been consistently prioritized in potato breeding, while allelic variation pattern of genes that underlie these traits is less explored. Results Here, we focused on
Externí odkaz:
https://doaj.org/article/9e8028bfe2ba487daa94745d03e286bc
Autor:
Natascha van Lieshout, Ate van der Burgt, Michiel E. de Vries, Menno ter Maat, David Eickholt, Danny Esselink, Martijn P. W. van Kaauwen, Linda P. Kodde, Richard G. F. Visser, Pim Lindhout, Richard Finkers
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 10, Pp 3489-3495 (2020)
With the rapid expansion of the application of genomics and sequencing in plant breeding, there is a constant drive for better reference genomes. In potato (Solanum tuberosum), the third largest food crop in the world, the related species S. phureja,
Externí odkaz:
https://doaj.org/article/2eeee281f75e43c5aa3e1036cecdd366
Autor:
Jolanda van Leeuwen, Carles Pons, Guihong Tan, Zi Yang Wang, Jing Hou, Jochen Weile, Marinella Gebbia, Wendy Liang, Ermira Shuteriqi, Zhijian Li, Maykel Lopes, Matej Ušaj, Andreia Dos Santos Lopes, Natascha van Lieshout, Chad L Myers, Frederick P Roth, Patrick Aloy, Brenda J Andrews, Charles Boone
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 9, Pp 1-24 (2020)
Abstract Essential genes tend to be highly conserved across eukaryotes, but, in some cases, their critical roles can be bypassed through genetic rewiring. From a systematic analysis of 728 different essential yeast genes, we discovered that 124 (17%)
Externí odkaz:
https://doaj.org/article/27e5a5f4f3414f1c97c8f31d1a196803
Autor:
Natascha van Lieshout, Martijn van Kaauwen, Linda Kodde, Paul Arens, Marinus J M Smulders, Richard G F Visser, Richard Finkers
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 12, Iss 1 (2021)
AbstractChrysanthemum is among the top 10 cut, potted, and perennial garden flowers in the world. Despite this, to date, only the genomes of two wild diploid chrysanthemums have been sequenced and assembled. Here, we present the most complete and con
Externí odkaz:
https://doaj.org/article/3c6f6edc8fbb403c8fd1c12aeac0ed24
Autor:
Jochen Weile, Song Sun, Atina G Cote, Jennifer Knapp, Marta Verby, Joseph C Mellor, Yingzhou Wu, Carles Pons, Cassandra Wong, Natascha van Lieshout, Fan Yang, Murat Tasan, Guihong Tan, Shan Yang, Douglas M Fowler, Robert Nussbaum, Jesse D Bloom, Marc Vidal, David E Hill, Patrick Aloy, Frederick P Roth
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 12, Pp 1-17 (2017)
Abstract Although we now routinely sequence human genomes, we can confidently identify only a fraction of the sequence variants that have a functional impact. Here, we developed a deep mutational scanning framework that produces exhaustive maps for h
Externí odkaz:
https://doaj.org/article/bdf5a797af864ab19cb037d766ead388
Autor:
Genevieve Hoopes, Xiaoxi Meng, John P. Hamilton, Sai Reddy Achakkagari, Fernanda de Alves Freitas Guesdes, Marie E. Bolger, Joseph J. Coombs, Danny Esselink, Natalie R. Kaiser, Linda Kodde, Maria Kyriakidou, Brian Lavrijssen, Natascha van Lieshout, Rachel Shereda, Heather K. Tuttle, Brieanne Vaillancourt, Joshua C. Wood, Jan M. de Boer, Nolan Bornowski, Peter Bourke, David Douches, Herman J. van Eck, Dave Ellis, Max J. Feldman, Kyle M. Gardner, Johannes C.P. Hopman, Jiming Jiang, Walter S. De Jong, Joseph C. Kuhl, Richard G. Novy, Stan Oome, Vidyasagar Sathuvalli, Ek Han Tan, Remco A. Ursum, M. Isabel Vales, Kelly Vining, Richard G.F. Visser, Jack Vossen, G. Craig Yencho, Noelle L. Anglin, Christian W.B. Bachem, Jeffrey B. Endelman, Laura M. Shannon, Martina V. Strömvik, Helen H. Tai, Björn Usadel, C. Robin Buell, Richard Finkers
Publikováno v:
Molecular Plant, 15(3), 520-536
Molecular Plant 15 (2022) 3
MOLECULAR PLANT
Molecular plant 15(3), 520-536 (2022). doi:10.1016/j.molp.2022.01.003
Molecular Plant 15 (2022) 3
MOLECULAR PLANT
Molecular plant 15(3), 520-536 (2022). doi:10.1016/j.molp.2022.01.003
Cultivated potato is a clonally propagated autotetraploid species with a highly heterogeneous genome. Phased assemblies of six cultivars including two chromosome-scale phased genome assemblies revealed extensive allelic diversity, including altered c
Autor:
Richard Finkers, Richard G. F. Visser, Martijn van Kaauwen, L.P. Kodde, Natascha van Lieshout, Paul Arens, Marinus J. M. Smulders
Publikováno v:
G3: Genes, Genomes, Genetics, 12(1)
G3: Genes, Genomes, Genetics 12 (2022) 1
G3: Genes, Genomes, Genetics, Vol 12, Iss 1 (2021)
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics 12 (2022) 1
G3: Genes, Genomes, Genetics, Vol 12, Iss 1 (2021)
G3: Genes|Genomes|Genetics
Chrysanthemum is among the top 10 cut, potted, and perennial garden flowers in the world. Despite this, to date, only the genomes of two wild diploid chrysanthemums have been sequenced and assembled. Here, we present the most complete and contiguous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f9577e8ed339b80cf2e884e099d319
https://research.wur.nl/en/publications/de-novo-whole-genome-assembly-of-chrysanthemum-makinoi-a-key-wild
https://research.wur.nl/en/publications/de-novo-whole-genome-assembly-of-chrysanthemum-makinoi-a-key-wild
Autor:
Eyal Simonovsky, Joseph C. Mellor, Amélie Dricot, Marc Vidal, Liana Goehring, Miquel Duran-Frigola, Florian Goebels, Dayag Sheykhkarimli, Thomas Rolland, Murat Tasan, John Rasla, Steffi De Rouck, Carles Pons, Sadie Schlabach, Yoseph Kassa, Claudia Colabella, Dong-Sic Choi, Yves Jacob, Joseph N. Paulson, Javier De Las Rivas, Madeleine F. Hardy, Francisco J. Campos-Laborie, Xinping Yang, Soon Gang Choi, Frederick P. Roth, Kerstin Spirohn, Nishka Kishore, Luke Lambourne, Cassandra D’Amata, Dawit Balcha, Adriana San-Miguel, Anupama Yadav, Anjali Gopal, Suet-Feung Chin, Suzanne Gaudet, Yang Wang, István Kovács, Elodie Hatchi, Natascha van Lieshout, Michael A. Calderwood, Yu Xia, Gloria M. Sheynkman, Robert J. Weatheritt, Marinella Gebbia, Atina G. Cote, Bridget E. Begg, Mohamed Helmy, Katja Luck, Bridget Teeking, Quan Zhong, Serena Landini, David E. Hill, Sudharshan Rangarajan, Georges Coppin, Ghazal Haddad, Omer Basha, Carl Pollis, Dylan Markey, Alice Desbuleux, Hanane Ennajdaoui, Dae-Kyum Kim, Vincent Tropepe, Roujia Li, Steven Deimling, Jennifer J. Knapp, Jan Tavernier, Mariana Babor, Benoit Charloteaux, Gary D. Bader, Alexander O. Tejeda, Aaron Richardson, Ruth Brignall, Ashyad Rayhan, Irma Lemmens, Tong Hao, Christian Bowman-Colin, Janusz Rak, David De Ridder, Jochen Weile, Wenting Bian, Jean-Claude Twizere, Patrick Aloy, Esti Yeger-Lotem, Meaghan Daley, Tiziana M. Cafarelli, Andrew MacWilliams, Miles W. Mee, Yun Shen
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature
Nature, Nature Publishing Group, 2020, 580 (7803), pp.402-408. ⟨10.1038/s41586-020-2188-x⟩
Nature, 2020, 580 (7803), pp.402-408. ⟨10.1038/s41586-020-2188-x⟩
instname
Nature
Nature, Nature Publishing Group, 2020, 580 (7803), pp.402-408. ⟨10.1038/s41586-020-2188-x⟩
Nature, 2020, 580 (7803), pp.402-408. ⟨10.1038/s41586-020-2188-x⟩
et al.
Global insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype–phenotype relationships1,2. Here we present a human ‘all-by-all’ reference interact
Global insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype–phenotype relationships1,2. Here we present a human ‘all-by-all’ reference interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faac39e9886775ddfef26fed76c6c35f
http://hdl.handle.net/10261/222715
http://hdl.handle.net/10261/222715
Autor:
Madeleine F. Hardy, Bridget Teeking, Francisco J. Campos-Laborie, Dayag Sheykhkarimli, Dawit Balcha, Anjali Gopal, Marinella Gebbia, Ashyad Rayhan, Carles Pons, Gloria M. Sheynkman, Yves Jacob, Suzanne Gaudet, Aaron Richardson, Yoseph Kassa, Elodie Hatchi, Kerstin Spirohn, Dong-Sic Choi, Yu Xia, Eyal Simonovsky, David E. Hill, Hanane Ennajdaoui, Steven Deimling, Joseph N. Paulson, Natascha van Lieshout, Vincent Tropepe, Michael A. Calderwood, István Kovács, Gary D. Bader, Luke Lambourne, Sudharshan Rangarajan, Tiziana M. Cafarelli, Carl Pollis, Suet-Feung Chin, Alice Desbuleux, Andrew MacWilliams, Amélie Dricot, Jean-Claude Twizere, Patrick Aloy, Atina G. Cote, Marc Vidal, Jan Tavernier, Javier De Las Rivas, Cassandra D’Amata, Alexander O. Tejeda, Esti Yeger-Lotem, Liana Goehring, Joseph C. Mellor, Meaghan Daley, Irma Lemmens, Soon Gang Choi, Christian Bowman-Colin, Ghazal Haddad, Janusz Rak, Florian Goebels, Robert J. Weatheritt, Mariana Babor, Yang Wang, Thomas Rolland, Steffi De Rouck, Jochen Weile, Serena Landini, John Rasla, Sadie Schlabach, Nishka Kishore, Bridget E. Begg, Ruth Brignall, Quan Zhong, Tong Hao, David De Ridder, Claudia Colabella, Frederick P. Roth, Anupama Yadav, Mohamed Helmy, Katja Luck, Omer Basha, Dae-Kyum Kim, Benoit Charloteaux, Georges Coppin, Dylan Markey, Roujia Li, Miquel Duran-Frigola, Adriana San-Miguel, Wenting Bian, Miles W. Mee, Jennifer J. Knapp, Yun Shen, Murat Tasan, Xinping Yang
Publikováno v:
Nature
Global insights into cellular organization and function require comprehensive understanding of interactome networks. Similar to how a reference genome sequence revolutionized human genetics, a reference map of the human interactome network is critica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0dcc8c7bb64a39a5f3d25ef82f4debb
https://doi.org/10.1101/605451
https://doi.org/10.1101/605451
Autor:
Frederick P. Roth, Jochen Weile, Yingzhou Wu, Natascha van Lieshout, Marc Vidal, Chi-Huey Wong, Marta Verby, Song Sun, Murat Tasan, Shan Yang, Guihong Tan, David E. Hill, Joseph C. Mellor, Patrick Aloy, Jesse D. Bloom, Jennifer J. Knapp, Fan Yang, Douglas M. Fowler, Carles Pons, Atina G. Cote, Robert L. Nussbaum
Publikováno v:
Molecular Systems Biology
Although we now routinely sequence human genomes, we can confidently identify only a fraction of the sequence variants that have a functional impact. Here, we developed a deep mutational scanning framework that produces exhaustive maps for human miss