Severe Recurrent Hypoglycemia after Gastric Bypass Surgery

Autor: Natascha Potoczna, Kaspar Z’graggen, Fritz F. Horber, Frank Walther, Rudolf Steffen, Paul Komminoth, Ruggero Biral, Ahmed Guweidhi

Publikováno v: Obesity Surgery. 18:981-988

Bariatric surgery is, at present, the most effective method to achieve major, long-term weight loss in severely obese patients. Recently, severe recurrent symptomatic hyperinsulinemic hypoglycemia was described as a consequence of gastric bypass surg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c771ba9d23b932b0ab8f5eb0bb45a4
https://doi.org/10.1007/s11695-008-9480-4

Prevalence of Melanocortin-4 Receptor Deficiency in Europeans and Their Age-Dependent Penetrance in Multigenerational Pedigrees

Autor: Beverley Balkau, David Meyre, Natascha Potoczna, Karen Tan, Fritz F. Horber, I. Sadaf Farooqi, Vincent Vatin, Jean Tichet, Fanny Stutzmann, Christian Dina, Béatrice Jouret, Stephen O'Rahilly, Philippe Froguel

Publikováno v: Diabetes

OBJECTIVE— Melanocortin-4 receptor (MC4R) deficiency is the most frequent genetic cause of obesity. However, there is uncertainty regarding the degree of penetrance of this condition, and the putative impact of the environment on the development of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc90a25100b81f79c167b39c2a405dee
http://europepmc.org/articles/PMC2518504

Management of failed adjustable gastric banding

Autor: Thomas Ricklin, Laurent Biertho, Natascha Potoczna, Grazyna Piec, Ruth Branson, Fritz F. Horber, Rudolf Steffen

Publikováno v: Surgery. 137:33-41

Background About 100,000 adjustable gastric band placements have been performed worldwide, but more than 10% of patients have needed reoperation for insufficient weight loss or device-related complications. This study investigates the complications f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13cfa24c63d52130ad9bbc756956a81a
https://doi.org/10.1016/j.surg.2004.06.007

G protein polymorphisms do not predict weight loss and improvement of hypertension in severely obese patients

Autor: Thomas Ricklin, Rudolph Steffen, Natascha Potoczna, Klaus-Ulrich Lentes, Fritz F. Horber, Maria M. Wertli

Publikováno v: Journal of Gastrointestinal Surgery. 8:862-868

Both the gene encoding the alpha subunit of G stimulatory proteins (GNAS1) and the beta3 subunit gene (GNB3) of G proteins are associated with obesity and/or hypertension. Moreover, the TT/TC825 polymorphism of GNB3 predicts greater weight loss than

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62944fb78bd543d4e8c8251559d80cb1
https://doi.org/10.1016/j.gassur.2004.08.004

Variation in FTO contributes to childhood obesity and severe adult obesity

Autor: Stéphane Cauchi, Cécile Lecoeur, Peter Kovacs, Jacques Weill, Jérôme Delplanque, Pierre Bougnères, Claire Levy-Marchal, Vincent Vatin, Wieland Kiess, Serge Hercberg, Sophie Gallina, Emmanuelle Durand, Lena M. S. Carlsson, Jean-Claude Chèvre, Emmanuel Vaillant, Natascha Potoczna, Beverley Balkau, Antje Körner, Catherine Le Stunff, Juan Ruiz, François Pattou, Fritz F. Horber, David Meyre, Philippe Froguel, Michel Marre, Peter Jacobson, Christian Dina

Publikováno v: Nature Genetics
Nature Genetics, Nature Publishing Group, 2007, 39 (6), pp.724-6. ⟨10.1038/ng2048⟩
Nature Genetics, 2007, 39 (6), pp.724-6. ⟨10.1038/ng2048⟩
Nature Genetics, Nature Publishing Group, 2007, 39 (6), pp.724-6. 〈10.1038/ng2048〉

The authors identified a set of SNPs in the first intron of the FTO (fat mass and obesity associated) gene on chromosome 16q12.2 that is consistently strongly associated with early-onset and severe obesity in both adults and children of European ance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578b645435567abee0e07f4b5e548a2b
https://doi.org/10.1038/ng2048