Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Natascha Fussi"'
Autor:
Günter U. Höglinger, Wolfgang Wurst, Matthias Höllerhage, Natascha Fussi, Christian Behrends, Thomas W. Rösler
Publikováno v:
Neuropharmacology 149, 13-26 (2019). doi:10.1016/j.neuropharm.2019.01.023
Pathological aggregates of alpha-synuclein are the common hallmarks of synucleinopathies, including Parkinson's disease. There is currently no disease-modifying therapy approved for neurodegenerative synucleinopathies. The induction of macroautophagy
Autor:
Niko-Petteri Nykänen, Christian Behrends, Tasnim Chakroun, Thomas W. Rösler, Günter U. Höglinger, Matthias Höllerhage, Wolfgang Wurst, Natascha Fussi, Thomas Koeglsperger
Publikováno v:
Cell Death & Disease
Cell death & disease 9(7), 757 (2018). doi:10.1038/s41419-018-0816-2
Cell Death Dis. 9:757 (2018)
Cell Death and Disease, Vol 9, Iss 7, Pp 1-14 (2018)
Cell death & disease 9(7), 757 (2018). doi:10.1038/s41419-018-0816-2
Cell Death Dis. 9:757 (2018)
Cell Death and Disease, Vol 9, Iss 7, Pp 1-14 (2018)
Accumulation of pathological α-synuclein aggregates plays a major role in Parkinson’s disease. Macroautophagy is a mechanism to degrade intracellular protein aggregates by wrapping them into autophagosomes, followed by fusion with lysosomes. We ha
Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy.
Autor:
Fussi, Natascha, Höllerhage, Matthias, Chakroun, Tasnim, Nykänen, Niko-Petteri, Rösler, Thomas W., Koeglsperger, Thomas, Wurst, Wolfgang, Behrends, Christian, Höglinger, Günter U.
Publikováno v:
Cell Death & Disease; Jul2018, Vol. 9 Issue 7, p1-14, 14p