Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Natascha Brigo"'
Autor:
Marc Herb, Valentin Schatz, Karina Hadrian, Deniz Hos, Bohdan Holoborodko, Jonathan Jantsch, Natascha Brigo
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Macrophages play a pivotal role in the innate immune response. While their most characteristic function is phagocytosis, it is important not to solely characterize macrophages by this activity. Their crucial roles in body development, homeostasis, re
Externí odkaz:
https://doaj.org/article/804c53ae390f403bb73b96554112616b
Autor:
Mario Gietl, Francesco Burkert, Stefanie Hofer, Johanna M. Gostner, Thomas Sonnweber, Ivan Tancevski, Alex Pizzini, Sabina Sahanic, Andrea Schroll, Natascha Brigo, Alexander Egger, Rosa Bellmann-Weiler, Judith Löffler-Ragg, Günter Weiss, Katharina Kurz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Research into the molecular basis of disease trajectory and Long-COVID is important to get insights toward underlying pathophysiological processes. The objective of this study was to investigate inflammation-mediated changes of metabolism in
Externí odkaz:
https://doaj.org/article/c446241408394e658cbf0ef687b653f0
Autor:
Philipp Grubwieser, Natascha Brigo, Markus Seifert, Manuel Grander, Igor Theurl, Manfred Nairz, Günter Weiss, Christa Pfeifhofer-Obermair
Publikováno v:
Bio-Protocol, Vol 14, Iss 3 (2024)
Macrophages are at the center of innate immunity and iron metabolism. In the case of an infection, macrophages adapt their cellular iron metabolism to deprive iron from invading bacteria to combat intracellular bacterial proliferation. A concise eval
Externí odkaz:
https://doaj.org/article/65bbdb9712d04ce9a1aa34a03c5d3c9b
Autor:
Christoph Grander, Moritz Meyer, Daniel Steinacher, Thierry Claudel, Bela Hausmann, Petra Pjevac, Felix Grabherr, Georg Oberhuber, Manuel Grander, Natascha Brigo, Almina Jukic, Julian Schwärzler, Günter Weiss, Timon E. Adolph, Michael Trauner, Herbert Tilg
Publikováno v:
JHEP Reports, Vol 5, Iss 11, Pp 100872- (2023)
Background & Aims: Alcohol-related liver disease (ALD) is a global healthcare challenge with limited treatment options. 24-Norursodeoxycholic acid (NorUDCA) is a synthetic bile acid with anti-inflammatory properties in experimental and human cholesta
Externí odkaz:
https://doaj.org/article/604fc6dffe2b445992c1e43edd5e7284
Autor:
Philipp Grubwieser, Richard Hilbe, Clemens Michael Gehrer, Manuel Grander, Natascha Brigo, Alexander Hoffmann, Markus Seifert, Sylvia Berger, Igor Theurl, Manfred Nairz, Günter Weiss
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
BackgroundKlebsiella pneumoniae (KP) is a major cause of hospital-acquired infections, such as pneumonia. Moreover, it is classified as a pathogen of concern due to sprawling anti-microbial resistance. During infection, the gram-negative pathogen is
Externí odkaz:
https://doaj.org/article/80faed13abd34ef386fe5da2c3e4468c
Autor:
Natascha Brigo, Philipp Grubwieser, Igor Theurl, Manfred Nairz, Günter Weiss, Christa Pfeifhofer-Obermair
Publikováno v:
Bio-Protocol, Vol 13, Iss 3 (2023)
Macrophages are at the center of innate immunity and are the main target cells of the intracellular pathogen Salmonella enterica serovar Typhi. The production of reactive oxygen and nitrogen species (ROS/RNS) is the host’s early response to invadin
Externí odkaz:
https://doaj.org/article/646d1f2829d44c4fb3e5457c1795dc5f
Autor:
Lara Valente de Souza, Alexander Hoffmann, Christine Fischer, Verena Petzer, Malte Asshoff, Igor Theurl, Piotr Tymoszuk, Markus Seifert, Natascha Brigo, Richard Hilbe, Egon Demetz, Laura Von Raffay, Sylvia Berger, Marina Barros-Pinkelnig, Guenter Weiss
Publikováno v:
Haematologica, Vol 108, Iss 1 (2022)
Anemia is a major health issue and associated with increased morbidity. Iron deficiency anemia (IDA) is the most prevalent, followed by anemia of chronic disease (ACD). IDA and ACD often co-exist, challenging diagnosis and treatment. While iron suppl
Externí odkaz:
https://doaj.org/article/74640c841f214ed6b2f5f716b2ee12d4
Publikováno v:
Bio-Protocol, Vol 12, Iss 11 (2022)
Macrophages are important for host defense against intracellular pathogens like Salmonella and can be differentiated into two major subtypes. M1 macrophages, which are pro-inflammatory and induce antimicrobial immune effector mechanisms, including th
Externí odkaz:
https://doaj.org/article/051952e459054d07a539dcc4f1d61cef
Autor:
Katharina Obermoser, Natascha Brigo, Andrea Schroll, Pablo Monfort-Lanzas, Johanna M. Gostner, Sabine Engl, Simon Geisler, Miriam Knoll, Harald Schennach, Günter Weiss, Dietmar Fuchs, Rosa Bellmann-Weiler, Katharina Kurz
Publikováno v:
Metabolites, Vol 13, Iss 5, p 639 (2023)
Post-infectious fatigue is a common complication that can lead to decreased physical efficiency, depression, and impaired quality of life. Dysbiosis of the gut microbiota has been proposed as a contributing factor, as the gut–brain axis plays an im
Externí odkaz:
https://doaj.org/article/1f6766f057f644ef8908e4dec90ec4a5
Autor:
Natascha Brigo, Emely Neumaier, Christa Pfeifhofer-Obermair, Philipp Grubwieser, Sabine Engl, Sylvia Berger, Markus Seifert, Vera Reinstadler, Herbert Oberacher, Günter Weiss
Publikováno v:
Cells, Vol 12, Iss 8, p 1164 (2023)
Priming of macrophages with interferon-gamma (IFNγ) or interleukin-4 (IL-4) leads to polarisation into pro-inflammatory or anti-inflammatory subtypes, which produce key enzymes such as inducible nitric oxide synthase (iNOS) and arginase 1 (ARG1), re
Externí odkaz:
https://doaj.org/article/e9dcfba08e2b403fa86c577ac484fca2