Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Natasa Broit"'
Autor:
Kevin Hendrawan, Kelly M Brooks, Pei-Yi Yap, Blake Ferguson, Motoko Koyama, Herlina Handoko, Jenny Johns, Natasa Broit, Praphaporn Stewart, Daniel Shelley, Tracey McMahon, Yi Chieh Lim, Giovanni Appendino, Jason K Cullen, Zara C Bruce, Steven M Ogbourne, Paul W Reddell, Glen M Boyle, Peter G Parsons, Jacinta L Simmons, Emily S Wilson, Marjorie M A de Souza, Tam Hong Nguyen, Alberto Pagani, Victoria A Gordon
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Tigilanol tiglate (TT) is a protein kinase C (PKC)/C1 domain activator currently being developed as an intralesional agent for the treatment of various (sub)cutaneous malignancies. Previous work has shown that intratumoral (I.T.) injection
Externí odkaz:
https://doaj.org/article/756c2bca74d94c10bc6e590de097d302
Autor:
Alisa M. Goldstein, PhD, Richard Qin, BS, Emily Y. Chu, MD, PhD, David E. Elder, MBChB, Daniela Massi, MD, PhD, David J. Adams, PhD, Paul W. Harms, MD, PhD, Carla Daniela Robles-Espinoza, PhD, Julia A. Newton-Bishop, MD, PhD, D. Timothy Bishop, PhD, Mark Harland, PhD, Elizabeth A. Holland, BSc, Anne E. Cust, PhD, Helen Schmid, MPH, Graham J. Mann, MBBS, PhD, Susana Puig, MD, PhD, Miriam Potrony, PhD, Llucia Alos, MD, PhD, Eduardo Nagore, MD, PhD, David Millán-Esteban, PhD, Nicholas K. Hayward, PhD, Natasa Broit, PhD, Jane M. Palmer, RN, Vaishnavi Nathan, PhD, Elizabeth G. Berry, MD, Esteban Astiazaran-Symonds, MD, Xiaohong R. Yang, PhD, Margaret A. Tucker, MD, Maria Teresa Landi, MD, PhD, Ruth M. Pfeiffer, PhD, Michael R. Sargen, MD
Publikováno v:
JAAD International, Vol 11, Iss , Pp 43-51 (2023)
Background: Spitzoid morphology in familial melanoma has been associated with germline variants in POT1, a telomere maintenance gene (TMG), suggesting a link between telomere biology and spitzoid differentiation. Objective: To assess if familial mela
Externí odkaz:
https://doaj.org/article/b6d3451b882d49dc952ed23a5da93142
Autor:
Priscila O. de Lima, Natasa Broit, Johnson D. Huang, Jae H. Lim, Damien J. Gardiner, Ian S. Brown, Benedict J. Panizza, Glen M. Boyle, Fiona Simpson
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionCutaneous squamous cell carcinoma of the head and neck (cSCCHN) can metastasize by invading nerves and spread toward the central nervous system. This metastatic process is called perineural invasion (PNI) and spread (PNS). An in vivo scia
Externí odkaz:
https://doaj.org/article/2c5024cdd8094be2929d27f498303ef0
Autor:
Jason K. Cullen, Glen M. Boyle, Pei-Yi Yap, Stefan Elmlinger, Jacinta L. Simmons, Natasa Broit, Jenny Johns, Blake Ferguson, Lidia A. Maslovskaya, Andrei I. Savchenko, Paul Malek Mirzayans, Achim Porzelle, Paul V. Bernhardt, Victoria A. Gordon, Paul W. Reddell, Alberto Pagani, Giovanni Appendino, Peter G. Parsons, Craig M. Williams
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The long-standing perception of Protein Kinase C (PKC) as a family of oncoproteins has increasingly been challenged by evidence that some PKC isoforms may act as tumor suppressors. To explore the hypothesis that activation, rather than inhib
Externí odkaz:
https://doaj.org/article/48af2e8d91fb499798d2ad925238a5a8
Autor:
Felicity Newell, James S. Wilmott, Peter A. Johansson, Katia Nones, Venkateswar Addala, Pamela Mukhopadhyay, Natasa Broit, Carol M. Amato, Robert Van Gulick, Stephen H. Kazakoff, Ann-Marie Patch, Lambros T. Koufariotis, Vanessa Lakis, Conrad Leonard, Scott Wood, Oliver Holmes, Qinying Xu, Karl Lewis, Theresa Medina, Rene Gonzalez, Robyn P. M. Saw, Andrew J. Spillane, Jonathan R. Stretch, Robert V. Rawson, Peter M. Ferguson, Tristan J. Dodds, John F. Thompson, Georgina V. Long, Mitchell P. Levesque, William A. Robinson, John V. Pearson, Graham J. Mann, Richard A. Scolyer, Nicola Waddell, Nicholas K. Hayward
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Acral melanoma occurs on the soles of the feet, palms of the hands and in nail beds. Here, the authors reports the genomic landscape of 87 acral melanomas and find that some tumors harbor a UV signature and that the tumors are diverse at the levels o
Externí odkaz:
https://doaj.org/article/953bcceaafac4fed9eb837e6a8612ce4
Autor:
Peter A. Johansson, Kelly Brooks, Felicity Newell, Jane M. Palmer, James S. Wilmott, Antonia L. Pritchard, Natasa Broit, Scott Wood, Matteo S. Carlino, Conrad Leonard, Lambros T. Koufariotis, Vaishnavi Nathan, Aaron B. Beasley, Madeleine Howlie, Rebecca Dawson, Helen Rizos, Chris W. Schmidt, Georgina V. Long, Hayley Hamilton, Jens F. Kiilgaard, Timothy Isaacs, Elin S. Gray, Olivia J. Rolfe, John J. Park, Andrew Stark, Graham J. Mann, Richard A. Scolyer, John V. Pearson, Nicolas van Baren, Nicola Waddell, Karin W. Wadt, Lindsay A. McGrath, Sunil K. Warrier, William Glasson, Nicholas K. Hayward
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Uveal melanoma has a propensity to metastasise. Here, the authors report the whole genome sequence of 103 uveal melanomas and find that the tumour mutational burden is variable and that two subsets of tumours are characterised by MBD4 mutations and a
Externí odkaz:
https://doaj.org/article/58e3d3d357e64515ab52e5174e676c01
Autor:
Felicity Newell, Peter A. Johansson, James S. Wilmott, Katia Nones, Vanessa Lakis, Antonia L. Pritchard, Serigne N. Lo, Robert V. Rawson, Stephen H. Kazakoff, Andrew J. Colebatch, Lambros T. Koufariotis, Peter M. Ferguson, Scott Wood, Conrad Leonard, Matthew H. Law, Kelly M. Brooks, Natasa Broit, Jane M. Palmer, Kasey L. Couts, Ismael A. Vergara, Georgina V. Long, Andrew P. Barbour, Omgo E. Nieweg, Brindha Shivalingam, William A. Robinson, Jonathan R. Stretch, Andrew J. Spillane, Robyn P.M. Saw, Kerwin F. Shannon, John F. Thompson, Graham J. Mann, John V. Pearson, Richard A. Scolyer, Nicola Waddell, Nicholas K. Hayward
Publikováno v:
Cancer Discovery. 12:2856-2879
Melanoma is a cancer of melanocytes, with multiple subtypes based on body site location. Cutaneous melanoma is associated with skin exposed to ultraviolet radiation; uveal melanoma occurs in the eyes; mucosal melanoma occurs in internal mucous membra
Autor:
Nicholas K. Hayward, Nicola Waddell, Richard A. Scolyer, John V. Pearson, Graham J. Mann, John F. Thompson, Kerwin F. Shannon, Robyn P.M. Saw, Andrew J. Spillane, Jonathan R. Stretch, William A. Robinson, Brindha Shivalingam, Omgo E. Nieweg, Andrew P. Barbour, Georgina V. Long, Ismael A. Vergara, Kasey L. Couts, Jane M. Palmer, Natasa Broit, Kelly M. Brooks, Matthew H. Law, Conrad Leonard, Scott Wood, Peter M. Ferguson, Lambros T. Koufariotis, Andrew J. Colebatch, Stephen H. Kazakoff, Robert V. Rawson, Serigne N. Lo, Antonia L. Pritchard, Vanessa Lakis, Katia Nones, James S. Wilmott, Peter A. Johansson, Felicity Newell
Supplementary Data from Comparative Genomics Provides Etiologic and Biological Insight into Melanoma Subtypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039a2ce67c76ce6b5dc56b00dcb51d0e
https://doi.org/10.1158/2159-8290.22541617.v1
https://doi.org/10.1158/2159-8290.22541617.v1
Autor:
Nicholas K. Hayward, Nicola Waddell, Richard A. Scolyer, John V. Pearson, Graham J. Mann, John F. Thompson, Kerwin F. Shannon, Robyn P.M. Saw, Andrew J. Spillane, Jonathan R. Stretch, William A. Robinson, Brindha Shivalingam, Omgo E. Nieweg, Andrew P. Barbour, Georgina V. Long, Ismael A. Vergara, Kasey L. Couts, Jane M. Palmer, Natasa Broit, Kelly M. Brooks, Matthew H. Law, Conrad Leonard, Scott Wood, Peter M. Ferguson, Lambros T. Koufariotis, Andrew J. Colebatch, Stephen H. Kazakoff, Robert V. Rawson, Serigne N. Lo, Antonia L. Pritchard, Vanessa Lakis, Katia Nones, James S. Wilmott, Peter A. Johansson, Felicity Newell
Melanoma is a cancer of melanocytes, with multiple subtypes based on body site location. Cutaneous melanoma is associated with skin exposed to ultraviolet radiation; uveal melanoma occurs in the eyes; mucosal melanoma occurs in internal mucous membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3d732adf31f4564decd8911f07bea9
https://doi.org/10.1158/2159-8290.c.6549709
https://doi.org/10.1158/2159-8290.c.6549709
Autor:
Antonia L. Pritchard, Nicholas K. Hayward, Felicity Newell, Sebastian T. Walpole, Chloe B. Rodgers, Peter A. Johansson, Natasa Broit
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eda93da96b97ce8b77e2de1a180fb54
https://doi.org/10.1158/1541-7786.22525851
https://doi.org/10.1158/1541-7786.22525851