Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Natarajan Arul Murugan"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3409 (2022)
The new variant of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), Omicron, has been quickly spreading in many countries worldwide. Compared to the original virus, Omicron is characterized by several mutations in its genomic region
Externí odkaz:
https://doaj.org/article/c4c982e7dac041559b675a14cf791a02
Autor:
Natarajan Arul Murugan, Artur Podobas, Davide Gadioli, Emanuele Vitali, Gianluca Palermo, Stefano Markidis
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 63 (2022)
Drug discovery is the most expensive, time-demanding, and challenging project in biopharmaceutical companies which aims at the identification and optimization of lead compounds from large-sized chemical libraries. The lead compounds should have high-
Externí odkaz:
https://doaj.org/article/7a921a0fa8b44990b1fb8ec666752ebf
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3244 (2021)
A wide variety of neurodegenerative diseases are characterized by the accumulation of protein aggregates in intraneuronal or extraneuronal brain regions. In Alzheimer’s disease (AD), the extracellular aggregates originate from amyloid-β proteins,
Externí odkaz:
https://doaj.org/article/c2c40c7e68e34ee399dcf5d9a3aa3f99
Autor:
Natarajan Arul Murugan, Charuvaka Muvva, Chitra Jeyarajpandian, Jeyaraman Jeyakanthan, Venkatesan Subramanian
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7648 (2020)
Monoamine oxidase B (MAOB) is expressed in the mitochondrial membrane and has a key role in degrading various neurologically active amines such as benzylamine, phenethylamine and dopamine with the help of Flavin adenine dinucleotide (FAD) cofactor. T
Externí odkaz:
https://doaj.org/article/f85dd605055f41089443d2d02c8a1bdf
Autor:
Joanna Bednarska, Robert Zaleśny, Guangjun Tian, Natarajan Arul Murugan, Hans Ågren, Wojciech Bartkowiak
Publikováno v:
Molecules, Vol 22, Iss 10, p 1643 (2017)
We have examined several approaches relying on the Polarizable Embedding (PE) scheme to predict optical band shapes for two chalcone molecules in methanol solution. The PE-TDDFT and PERI-CC2 methods were combined with molecular dynamics simulations,
Externí odkaz:
https://doaj.org/article/ed6fe81bf014413d964d0f42cad31f9f
Autor:
Sanjay Kumar Mohanty, Aayushi Mittal, Aakash Gaur, Saveena Solanki, Suvendu Kumar, Subhadeep Duari, Sakshi Arora, Vishakha Gautam, Nilesh Kumar Dixit, Tarini Shankar Ghosh, Debarka Sengupta, Shashi Kumar Gupta, Natarajan Arul Murugan, Gaurav Ahuja
Traditionally, the exogenous allosteric modulators of G protein-coupled receptors (GPCRs) have been extensively investigated due to their pharmacological significance. However, to date, only a handful of endogenous intracellular allosteric modulators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e157fcfea67ef6549606b1c6410fa6
https://doi.org/10.21203/rs.3.rs-2611000/v1
https://doi.org/10.21203/rs.3.rs-2611000/v1
Publikováno v:
Materials Advances. 3:4069-4087
The paradigm of advanced materials has grown exponentially over the last decade, with their new dimensions including digital design, dynamics, and functions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b10e18202b9ba098d2d45446f64a3010
https://doi.org/10.1039/d2ma00067a
https://doi.org/10.1039/d2ma00067a
Publikováno v:
Parallel Processing and Applied Mathematics ISBN: 9783031304415
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49a73d8b07d5f0e67ea074e98e6ebfe7
https://doi.org/10.1007/978-3-031-30442-2_25
https://doi.org/10.1007/978-3-031-30442-2_25
Autor:
Vishakha Gautam, Rahul Gupta, Deepti Gupta, Anubhav Ruhela, Aayushi Mittal, Sanjay Kumar Mohanty, Sakshi Arora, Ria Gupta, Chandan Saini, Debarka Sengupta, Natarajan Arul Murugan, Gaurav Ahuja
Publikováno v:
Briefings in bioinformatics. 23(5)
Artificial intelligence (AI)-based computational techniques allow rapid exploration of the chemical space. However, representation of the compounds into computational-compatible and detailed features is one of the crucial steps for quantitative struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1798020552fbc0dee6f8a7e6f2e316d1
https://pubmed.ncbi.nlm.nih.gov/35868454
https://pubmed.ncbi.nlm.nih.gov/35868454
Autor:
Markidis, Natarajan Arul Murugan, Artur Podobas, Davide Gadioli, Emanuele Vitali, Gianluca Palermo, Stefano
Publikováno v:
Pharmaceuticals; Volume 15; Issue 1; Pages: 63
Drug discovery is the most expensive, time-demanding, and challenging project in biopharmaceutical companies which aims at the identification and optimization of lead compounds from large-sized chemical libraries. The lead compounds should have high-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::2045d6c4f3856c1b227dab2be5fd9f92