Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Natarajan, Ravendhran"'
Autor:
Man-Fung Yuen, Scott Fung, Xiaoli Ma, Tuan T. Nguyen, Tarek Hassanein, Hie-Won Hann, Magdy Elkhashab, Ronald G. Nahass, James S. Park, Ira M. Jacobson, Walid S. Ayoub, Steven-Huy Han, Edward J. Gane, Katie Zomorodi, Ran Yan, Julie Ma, Steven J. Knox, Luisa M. Stamm, Maurizio Bonacini, Frank Weilert, Alnoor Ramji, Michael Bennett, Natarajan Ravendhran, Sing Chan, Douglas T. Dieterich, Paul Yien Kwo, Eugene R. Schiff, Ho S. Bae, Jacob Lalezari, Kosh Agarwal, Mark S. Sulkowski
Publikováno v:
JHEP Reports, Vol 6, Iss 4, Pp 100999- (2024)
Background & Aims: The investigational first-generation core inhibitor vebicorvir (VBR) demonstrated safety and antiviral activity over 24 weeks in two phase IIa studies in patients with chronic HBV infection. In this long-term extension study, patie
Externí odkaz:
https://doaj.org/article/79c1f480374a43d2b19433829b3f31b0
Autor:
Steven Flamm, Eric Lawitz, Brian Borg, Michael Charlton, Charles Landis, K. Rajender Reddy, Mitchell Shiffman, Angel Alsina, Charissa Chang, Natarajan Ravendhran, Candido Hernandez, Christophe Hézode, Stacey Scherbakovsky, Renee-Claude Mercier, Didier Samuel
Publikováno v:
Viruses, Vol 15, Iss 10, p 2026 (2023)
A fixed-dose combination of sofosbuvir/velpatasvir (SOF/VEL) plus weight-based ribavirin (RBV) for 12 weeks is recommended for the treatment of patients with hepatitis C virus (HCV)-associated decompensated cirrhosis. However, large global studies, w
Externí odkaz:
https://doaj.org/article/620ad64d8bc644198848a98512cd84c1
Autor:
Man-Fung Yuen, Kosh Agarwal, Xiaoli Ma, Tuan T. Nguyen, Eugene R. Schiff, Hie-Won L. Hann, Douglas T. Dieterich, Ronald G. Nahass, James S. Park, Sing Chan, Steven-Huy B. Han, Edward J. Gane, Michael Bennett, Katia Alves, Marc Evanchik, Ran Yan, Qi Huang, Uri Lopatin, Richard Colonno, Julie Ma, Steven J. Knox, Luisa M. Stamm, Maurizio Bonacini, Ira M. Jacobson, Walid S. Ayoub, Frank Weilert, Natarajan Ravendhran, Alnoor Ramji, Paul Yien Kwo, Magdy Elkhashab, Tarek Hassanein, Ho S. Bae, Jacob P. Lalezari, Scott K. Fung, Mark S. Sulkowski
Publikováno v:
Journal of Hepatology. 77:642-652
HBV nucleos(t)ide reverse transcriptase inhibitors (NrtIs) do not completely suppress HBV replication. Previous reports indicate persistent viremia during NrtI treatment despite HBV DNA being undetectable. HBV core inhibitors may enhance viral suppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7a77f9cac5a69525b2790e5ecdf2d1
https://doi.org/10.1016/j.jhep.2022.04.005
https://doi.org/10.1016/j.jhep.2022.04.005
Autor:
Rohit Loomba, Arun J. Sanyal, Atsushi Nakajima, Brent A. Neuschwander-Tetri, Zachary D. Goodman, Stephen A. Harrison, Eric J. Lawitz, Nadege Gunn, Kento Imajo, Natarajan Ravendhran, Takemi Akahane, Bradly Boone, Masayuki Yamaguchi, Arkendu Chatterjee, Giridhar S. Tirucherai, Diane E. Shevell, Shuyan Du, Edgar D. Charles, Manal F. Abdelmalek
Publikováno v:
Clinical Gastroenterology and Hepatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2f1dc9503ff18b5769c70231a75e29a
https://doi.org/10.1016/j.cgh.2023.04.011
https://doi.org/10.1016/j.cgh.2023.04.011
Autor:
Maribel Rodriguez-Torres, Eric Läwitz, Bienvenido Yangco, Lennox Jeffers, Steven-Huy Han, Paul J. Thuluvath, Vinod Rustgi, Stephen Harrison, Reem Ghalib, John M. Vierling, Velimir Luketic, Philippe J. Zamor, Natarajan Ravendhran, Timothy R. Morgan, Brian Pearlman, Christopher O’Brien, Hicham Khallafi, Nikolaos Pyrsopoulos, George Kong, Fiona McPhee, Philip D. Yin, Eric Hughes, Michelle Treitel
Publikováno v:
Annals of Hepatology, Vol 15, Iss 6, Pp 834-845 (2016)
Background. Patient race and ethnicity have historically impacted HCV treatment response. This phase 3 study evaluated daclatasvir with peginterferon-alfa-2a/ribavirin (pegIFN alfa-2a/RBV) in treatment-naive black/African American (AA), Latino, and w
Externí odkaz:
https://doaj.org/article/758320977acf45fe990b1d476981cdbb
Autor:
Zobair Younossi, Naim Alkhouri, Ken Cusi, Scott Isaacs, Fasiha Kanwal, Mazen Noureddin, Rohit Loomba, Natarajan Ravendhran, Brian Lam, Khalil Nader, Andrei Racila, Fatema Nader, Linda Henry
Publikováno v:
Alimentary pharmacologytherapeuticsREFERENCES.
Patients with nonalcoholic fatty liver disease (NAFLD) with type 2 diabetes (T2D) or other components of metabolic syndrome are at high risk for disease progression. We proposed an algorithm to identify high-risk NAFLD patients in clinical practice u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b74c197bb4447ba076227dea71ac6c6c
https://pubmed.ncbi.nlm.nih.gov/36511349
https://pubmed.ncbi.nlm.nih.gov/36511349
Publikováno v:
Translational Gastroenterology and Hepatology. 8:10-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a3c946c9b1447965c1893881a7600e4
https://doi.org/10.21037/tgh-22-1
https://doi.org/10.21037/tgh-22-1
Autor:
Mark S Sulkowski, Scott K Fung, Xiaoli Ma, Tuan T Nguyen, Eugene R. Schiff, Hie-Won L Hann, Douglas T Dieterich, Ronald G Nahass, James S Park, Sing Chan, Steven-Huy B Han, Edward J Gane, Michael Bennett, Ran Yan, Jieming Liu, Julie Ma, Steven J Knox, Luisa M Stamm, Maurizio Bonacini, Ira M Jacobson, Walid S Ayoub, Frank Weilert, Natarajan Ravendhran, Alnoor Ramji, Paul Yien Kwo, Magdy Elkhashab, Tarek Hassanein, Ho S Bae, Jacob P Lalezari, Kosh Agarwal, Man-Fung Yuen
Publikováno v:
Journal of Hepatology. 77:S836-S837
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::137571ba2184b71442f5b32e56129cd9
https://doi.org/10.1016/s0168-8278(22)01968-7
https://doi.org/10.1016/s0168-8278(22)01968-7
Autor:
Mark S. Sulkowski, Kosh Agarwal, Xiaoli Ma, Tuan T. Nguyen, Eugene R. Schiff, Hie-Won L. Hann, Douglas T. Dieterich, Ronald G. Nahass, James S. Park, Sing Chan, Steven-Huy B. Han, Edward J. Gane, Michael Bennett, Katia Alves, Marc Evanchik, Ran Yan, Qi Huang, Uri Lopatin, Richard Colonno, Julie Ma, Steven J. Knox, Luisa M. Stamm, Maurizio Bonacini, Ira M. Jacobson, Walid S. Ayoub, Frank Weilert, Natarajan Ravendhran, Alnoor Ramji, Paul Yien Kwo, Magdy Elkhashab, Tarek Hassanein, Ho S. Bae, Jacob P. Lalezari, Scott K. Fung, Man-Fung Yuen
Publikováno v:
Journal of hepatology. 77(5)
Nucleos(t)ide reverse transcriptase inhibitors do not completely suppress HBV DNA in chronic HBV infection (cHBV). Vebicorvir (VBR) is an investigational core inhibitor that interferes with multiple aspects of HBV replication. This phase II trial eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b1959f900369042b7add8624579b93
https://pubmed.ncbi.nlm.nih.gov/35697332
https://pubmed.ncbi.nlm.nih.gov/35697332
Autor:
Roger Trinh, Akshanth R. Polepally, Natarajan Ravendhran, Leslie Bank, Paul J. Pockros, Robert Reindollar, Fred Poordad, Marisol Martinez, Michael S. Epstein, David E. Bernstein, David R. Nelson, Shahriar Sedghi, Michael R. Lucey, Preethi Krishnan, Kristina Unnebrink
Publikováno v:
Journal of Viral Hepatitis
Patients infected with hepatitis C virus (HCV) treated with interferon‐free direct‐acting antivirals may still require ribavirin. However, ribavirin is associated with adverse events that can limit its use. This open‐label, multicentre, Phase 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98a2630727fcd42cfacf6f7056bd160
https://doi.org/10.1111/jvh.13109
https://doi.org/10.1111/jvh.13109