Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Natalya V. Serbina"'
Autor:
Jonathan French, Alan C. Fisher, Brent J. Yamamoto, Natalya V. Serbina, Nestor Gonzales, Edward O'Connor, Lisa N. Henning, Annette M. Shadiack, Daniel C. Sanford, Sarah Carpenter, Gregory V. Stark, John Mondick, Leslie S. Casey
Publikováno v:
Antimicrobial Agents and Chemotherapy
Inhalational anthrax has high mortality even with antibiotic treatment, and antitoxins are now recommended as an adjunct to standard antimicrobial regimens. The efficacy of obiltoxaximab, a monoclonal antibody against anthrax protective antigen (PA),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b367abcaa8fd1a9dc925aa519dd358
https://doi.org/10.1128/aac.00972-16
https://doi.org/10.1128/aac.00972-16
Autor:
Daniel C. Sanford, Sarah Carpenter, Lisa N. Henning, Natalya V. Serbina, Nestor Gonzales, Edward O'Connor, Leslie S. Casey, Annette M. Shadiack, Brent J. Yamamoto
Publikováno v:
Antimicrobial Agents and Chemotherapy
The Centers for Disease Control and Prevention recommend adjunctive antitoxins when systemic anthrax is suspected. Obiltoxaximab, a monoclonal antibody against protective antigen (PA), is approved for treatment of inhalational anthrax in combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1675792ec3b66e84376e133b8699316f
http://europepmc.org/articles/PMC5038297
http://europepmc.org/articles/PMC5038297
Autor:
Benjamin G. Neel, Kyung-Hyun Park-Min, Stephen L. Nutt, Xiaojing Ma, Xiaoyu Hu, Lionel B. Ivashkiv, Natalya V. Serbina, Wentian Yang, Gerald Krystal
Publikováno v:
Immunity. 26:67-78
Intravenous immune globulin (IVIG) suppresses autoantibody-mediated inflammation by inducing and activating the inhibitory Fc receptor FcgammaRIIb and downstream negative signaling pathways. We investigated the effects of IVIG on cellular responses t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101a0c9fd13705b47fccd4b31044b635
https://doi.org/10.1016/j.immuni.2006.11.010
https://doi.org/10.1016/j.immuni.2006.11.010
Publikováno v:
Infection and Immunity. 72:1057-1064
Chemokine receptor 5 (CCR5) binds macrophage inflammatory protein 1α (MIP-1α), MIP-1β, RANTES, and members of the monocyte chemotactic protein family and is also a receptor for human immunodeficiency virus (HIV). CCR5 ligands can suppress HIV-1 en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58fc35241b0e305817de7798e7c8e108
https://doi.org/10.1128/iai.72.2.1057-1064.2004
https://doi.org/10.1128/iai.72.2.1057-1064.2004
Autor:
Natalya V. Serbina, Shizuo Akira, Eric G. Pamer, Barrett J. Rollins, Richard A. Flavell, William A. Kuziel
Publikováno v:
Immunity. 19(6):891-901
Microbial infections induce chemokine and cytokine cascades that coordinate innate immune defenses. Infection with the intracellular bacterial pathogen Listeria monocytogenes induces CCR2-dependent monocyte recruitment and activation, an essential re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b3c7abe6cc4eb744b90bac2c1a61c2
Autor:
Roman A. Tuma, Sujata Vijh, Grégoire Lauvau, Eric G. Pamer, Natalya V. Serbina, Tiffany Horng, Kristen M. Kerksiek, Philip Kong
Publikováno v:
Science. 294:1735-1739
Killed or inactivated vaccines targeting intracellular bacterial and protozoal pathogens are notoriously ineffective at generating protective immunity. For example, vaccination with heat-killedListeria monocytogenes(HKLM) is not protective, although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f404ffbf0bbdb56c4bedbae3635cf893
https://doi.org/10.1126/science.1064571
https://doi.org/10.1126/science.1064571
Autor:
Nancy M. Chiu, JoAnne L. Flynn, Taehoon Chun, Natalya V. Serbina, Dawn Nolt, Bin Wang, Chyung Ru Wang
Publikováno v:
Journal of Experimental Medicine. 193:1213-1220
Major histocompatibility complex (MHC) class I–restricted CD8+ T cells play a critical role in the protective immunity against Mycobacterium tuberculosis (Mtb). However, only a few Mtb peptides recognized by MHC class Ia–restricted CD8+ T cells h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac00d2946fbad9748cbeff47b4dd0cb4
https://doi.org/10.1084/jem.193.10.1213
https://doi.org/10.1084/jem.193.10.1213
Autor:
Pamela J. Ovendale, Steven G. Reed, JoAnne L. Flynn, Rhea N. Coler, Natalya V. Serbina, Fiona H. Day, Mark R. Alderson, Liqing Zhu, Antonio Campos-Neto, Steven P. Fling
Publikováno v:
The Journal of Immunology. 166:6227-6235
The development of an effective vaccine against Mycobacterium tuberculosis is a research area of intense interest. Mounting evidence suggests that protective immunity to M. tuberculosis relies on both MHC class II-restricted CD4+ T cells and MHC clas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf4847a61183f78af5d30e3e9c457fb
https://doi.org/10.4049/jimmunol.166.10.6227
https://doi.org/10.4049/jimmunol.166.10.6227
Publikováno v:
Infection and Immunity. 69:800-809
The interaction of microbes with dendritic cells (DCs) is likely to have an enormous impact on the initiation of the immune response against a pathogen. In this study, we compared the interaction ofMycobacterium tuberculosiswith murine bone marrow-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3dbab1bb3dd6ab51186204be6f3ea8
https://doi.org/10.1128/iai.69.2.800-809.2001
https://doi.org/10.1128/iai.69.2.800-809.2001
Autor:
Sungae Cho, Steffen Stenger, Robert L. Modlin, Sybille Thoma-Uszynski, Esteban Celis, JoAnne L. Flynn, Vijay Mehra, Barry R. Bloom, Richard J. Mazzaccaro, Natalya V. Serbina, Scott Southwood, Peter F. Barnes, Alessandro Sette
Publikováno v:
Proceedings of the National Academy of Sciences. 97:12210-12215
Studies of mouse models of tuberculosis (TB) infection have indicated a central role for MHC class I-restricted CD8+ T cells in protective immunity. To define antigens and epitopes ofMycobacterium tuberculosis(MTB) proteins that are presented by infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6372d431715b93581ecacf6be0be7c2
https://doi.org/10.1073/pnas.210391497
https://doi.org/10.1073/pnas.210391497