Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Natalya V Kaverina"'
Autor:
Natalya V Kaverina, Hiroyuki Kadoya, Diana G Eng, Michael E Rusiniak, Maria Luisa S Sequeira-Lopez, R Ariel Gomez, Jeffrey W Pippin, Kenneth W Gross, Janos Peti-Peterdi, Stuart J Shankland
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173891 (2017)
Podocyte depletion plays a major role in focal segmental glomerular sclerosis (FSGS). Because cells of the renin lineage (CoRL) serve as adult podocyte and parietal epithelial cell (PEC) progenitor candidates, we generated Ren1cCre/R26R-ConfettiTG/WT
Externí odkaz:
https://doaj.org/article/377f11c06fb4421e8b9d0334feb3b70e
Autor:
Abbal Koirala, Natalya V. Kaverina, Jeffrey W. Pippin, Shreeram Akilesh, Diana G. Eng, Carol Loretz, Yuliang Wang, Stuart J. Shankland
Publikováno v:
Kidney Int
Glomerular podocytes undergo structural and functional changes with advanced age, that increase susceptibility of aging kidneys to worse outcomes following superimposed glomerular diseases. To delineate transcriptional changes in podocytes in aged mi
Publikováno v:
Aging. 12:17601-17624
Healthy aging is typified by a progressive and absolute loss of podocytes over the lifespan of animals and humans. To test the hypothesis that a subset of glomerular parietal epithelial cell (PEC) progenitors transition to a podocyte fate with aging,
Autor:
Diana G. Eng, Markus Bitzer, Natalya V. Kaverina, Carol Loretz, Oliver Wessely, Yuliang Wang, Yuting Zeng, Christopher L. O’Connor, Uyen Tran, Anthony Chang, Stuart J. Shankland, Jeffrey W. Pippin
Kidney aging and its contribution to disease and its underlying mechanisms are not well understood. With an aging population, kidney health becomes an important medical and socioeconomic factor. We previously showed that podocytes isolated from aged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5db5ccf04a7b46fbdce06630e99a589
https://doi.org/10.1101/2021.10.26.466006
https://doi.org/10.1101/2021.10.26.466006
Autor:
Junting Ai, Margaret Veselits, Natalya V. Kaverina, Iannis Aifantis, Marcus R. Clark, Michael K. Okoreeh, Malay Mandal, Domenick E. Kennedy, Fotini Gounari, Kaitlin C. McLean, Mark Maienschein-Cline
Publikováno v:
Nature immunology
In B lymphopoiesis, activation of the pre-B cell antigen receptor (pre-BCR) is associated with both cell cycle exit and Igk recombination. Yet how the pre-BCR mediates these functions remains unclear. Here, we demonstrate that the pre-BCR initiates a
Autor:
Natalya V. Kaverina, Diana G. Eng, Tyler J. Chozinski, Benjamin S. Freedman, Jeffrey H. Miner, Jeffrey W. Pippin, J. Nathan Kutz, Stuart J. Shankland, Joshua C. Vaughan
Publikováno v:
Kidney International. 96:597-611
Podocytes are differentiated post-mitotic cells that cannot replace themselves after injury. Glomerular parietal epithelial cells are proposed to be podocyte progenitors. To test whether a subset of parietal epithelial cells transdifferentiate to a p
Autor:
Natalya V. Kaverina, Ilya V. Ulasov, Ting Xiao, Mikhail E. Platonov, Kadagidze Zg, Anton V. Borovjagin, Maciej S. Lesniak, M. A. Baryshnikova
Publikováno v:
Cancer Letters. 417:75-88
KISS1 tumor suppressor protein regulates cancer cell invasion via MMP9 metalloproteinase. Downregulation of KISS1 gene expression promotes progression of breast cancer and melanoma, resulting in the development of distant metastases. In the current s
Autor:
Natalya V. Kaverina, Diana G. Eng, Jeffrey W. Pippin, Stuart J. Shankland, Kenneth W. Gross, Anthony Chang, Ilse Daehn, Peter Hohenstein, Andrea D. Largent
Publikováno v:
Stem Cell Reports, Vol 9, Iss 4, Pp 1152-1166 (2017)
Stem Cell Reports
Kaverina, N V, Eng, D G, Largent, A D, Daehn, I, Chang, A, Gross, K W, Pippin, J W, Hohenstein, P & Shankland, S J 2017, ' Wt1 is necessary for the proliferation and migration of cells of renin lineage following podocyte depletion ', Stem Cell Reports, vol. 9, no. 4, pp. 1152-1166 . https://doi.org/10.1016/j.stemcr.2017.08.020
Stem Cell Reports
Kaverina, N V, Eng, D G, Largent, A D, Daehn, I, Chang, A, Gross, K W, Pippin, J W, Hohenstein, P & Shankland, S J 2017, ' Wt1 is necessary for the proliferation and migration of cells of renin lineage following podocyte depletion ', Stem Cell Reports, vol. 9, no. 4, pp. 1152-1166 . https://doi.org/10.1016/j.stemcr.2017.08.020
Summary Wilms' tumor suppressor 1 (WT1) plays an important role in cell proliferation and mesenchymal-epithelial balance in normal development and disease. Here, we show that following podocyte depletion in three experimental models, and in patients
Autor:
Jianing Wang, Junting Ai, Anthony Chang, Marcus R. Clark, Susan Westmoreland, Maryellen L. Giger, Yahui Peng, Lisa Olson, Li Lan, Vladimir M. Liarski, Stuart Perper, Li Chun Wang, Denisse Yanez, Kichul Ko, Natalya V. Kaverina, Yulei Jiang
Publikováno v:
Arthritis & Rheumatology. 68:2740-2751
Objective In lupus nephritis, tubulointerstitial inflammation (TII) is associated with in situ adaptive immune cell networks that amplify local tissue damage. Since conventional therapy appears ineffective for severe TII, and these patients often pro
Autor:
Anatoly Y. Baryshnikov, Kadagidze Zg, Ilya V. Ulasov, Dhimankrishna Ghosh, Charles Cobbs, Natalya V. Kaverina, Apollon I. Karseladze, M. A. Baryshnikova
Publikováno v:
Oncotarget
// Ilya V. Ulasov 1, 2, 3 , Natalya V. Kaverina 3, 4 , Dhimankrishna Ghosh 1 , Marya A. Baryshnikova 2, 3 , Zaira G. Kadagidze 3 , Apollon I. Karseladze 3 , Anatoly Y. Baryshnikov 2, 3 , Charles S. Cobbs 1 1 Swedish Neuroscience Institute, Center for