Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Natalya S. Egorova"'
Autor:
Lucy O. Ojomoko, Elena V. Kryukova, Natalya S. Egorova, Arthur I. Salikhov, Lyubov A. Epifanova, Daria A. Denisova, Alex R. Khomutov, Dmitry A. Sukhov, Alexander A. Vassilevski, Maxim A. Khomutov, Victor I. Tsetlin, Irina V. Shelukhina
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Oligoarginine peptides, known mostly for their cell-penetrating properties, are also inhibitors of the nicotinic acetylcholine receptors (nAChRs). Since octa-arginine (R8) inhibits α9α10 nAChR and suppresses neuropathic pain, we checked if other po
Externí odkaz:
https://doaj.org/article/ab66a8f41b6945c19f9cb45777684225
Autor:
Irina V. Shelukhina, Maxim N. Zhmak, Alexander V. Lobanov, Igor A. Ivanov, Alexandra I. Garifulina, Irina N. Kravchenko, Ekaterina A. Rasskazova, Margarita A. Salmova, Elena A. Tukhovskaya, Vladimir A. Rykov, Gulsara A. Slashcheva, Natalya S. Egorova, Inessa S. Muzyka, Victor I. Tsetlin, Yuri N. Utkin
Publikováno v:
Toxins, Vol 10, Iss 1, p 34 (2018)
Azemiopsin (Az), a linear peptide from the Azemiops feae viper venom, contains no disulfide bonds, is a high-affinity and selective inhibitor of nicotinic acetylcholine receptor (nAChR) of muscle type and may be considered as potentially applicable n
Externí odkaz:
https://doaj.org/article/1c3a1a5152d349a28255839e22ecb2e9
Autor:
Natalya S. Egorova, Tr. D. Nguyen, V. I. Tsetlin, Khoa Cuu Nguyen, Anh Ngoc Hoang, T. N. Nguyen, Q. N. Tran, Vladislav G. Starkov, Yu. N. Utkin
Publikováno v:
Doklady Biochemistry and Biophysics. 487:251-255
Three-finger snake neurotoxins are selective antagonists of some nicotinic acetylcholine receptor subtypes and are widely used to study these receptors. The peptide neurotoxin azemiopsin, recently isolated from the venom of Azemipos feae, is a select
Autor:
V. I. Tsetlin, Igor E. Kasheverov, Natalya S. Egorova, D. A. Senko, Ekaterina N. Spirova, D. S. Lebedev, Igor Ivanov, Elena V. Kryukova
Publikováno v:
Doklady Biochemistry and Biophysics. 483:313-315
Arginine-containing peptides R3, R8, and R16 were obtained by solid-phase peptide synthesis, and their binding to nicotinic acetylcholine receptors (nAChRs) of muscle and neuronal (α7) types was studied by competitive radioligand assay with the use
Autor:
Igor E. Kasheverov, Oksana V. Nekrasova, Marina V. Serebryakova, Natalya S. Egorova, Maxim N. Zhmak, Victor I. Tsetlin, Andrei M. Gigolaev, Igor Ivanov, Nikita A. Prokopev, Peter B. Oparin, Anh Ngoc Hoang, Denis S. Kudryavtsev, Yuri N. Utkin, Alexander A. Vassilevski
Publikováno v:
FEBS lettersReferences. 593(19)
Neurotoxins are among the main components of scorpion and snake venoms. Scorpion neurotoxins affect voltage-gated ion channels, while most snake neurotoxins target ligand-gated ion channels, mainly nicotinic acetylcholine receptors (nAChRs). We repor
Autor:
Margarita A Salmova, A. V. Lobanov, Natalya S. Egorova, G. A. Slashcheva, Victor I. Tsetlin, Maxim N. Zhmak, Elena A Tukhovskaya, Inessa S. Muzyka, Igor Ivanov, I. N. Kravchenko, Irina V. Shelukhina, Alexandra I. Garifulina, Ekaterina A Rasskazova, Yuri N. Utkin, V. A. Rykov
Publikováno v:
Toxins
Toxins; Volume 10; Issue 1; Pages: 34
Toxins, Vol 10, Iss 1, p 34 (2018)
Toxins; Volume 10; Issue 1; Pages: 34
Toxins, Vol 10, Iss 1, p 34 (2018)
Azemiopsin (Az), a linear peptide from the Azemiops feae viper venom, contains no disulfide bonds, is a high-affinity and selective inhibitor of nicotinic acetylcholine receptor (nAChR) of muscle type and may be considered as potentially applicable n
Autor:
Eugene V. Grishin, Peter V. Dubovskii, Olga V. Samsonova, Alexander S. Arseniev, Sergey A. Kozlov, Alexei V. Feofanov, Natalya S. Egorova, Alexander A. Vassilevski
Publikováno v:
FEBS Journal. 278:4382-4393
A unique 30-residue cationic peptide oxyopinin 4a (Oxt 4a) was identified in the venom of the lynx spider Oxyopes takobius (Oxyopidae). Oxt 4a contains a single N-terminally located disulfide bond, Cys4-Cys10, and is structurally different from any s
Publikováno v:
Biochimie. 93:227-241
Activity and action mechanisms of latarcin 2a (Ltc2a), an antimicrobial peptide from the venom of the spider Lachesana tarabaevi (Zodariidae), were studied in vitro on human cells. Cytotoxicity of Ltc2a for erythrocytes (EC(50) = 3.4 μM), leukocytes
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1778(10):2361-2367
Eph receptor tyrosine kinases (RTKs) are activated by a ligand-mediated dimerization in the plasma membrane and subjected to clusterization at a high local density of receptors and their membrane-anchored ligands. Interactions between transmembrane d
Autor:
Tatiana B. Stoilova, Andrey Y. Surovoy, Vadim T. Ivanov, Natalya S. Egorova, Sergey I. Kovalchuk
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1778(10):2026-2031
The development of the peptide-based vectors for the intracellular delivery of biologically active macromolecules has opened new prospects of their application in research and therapy. Earlier the amphipathic cell-penetrating peptide (CPP) Pep-1 was