Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Natalya Odoardi"'
Autor:
Sean Leonard, Hailey Guertin, Natalya Odoardi, Michael R. Miller, Maitray A. Patel, Mark Daley, Gediminas Cepinskas, Douglas D. Fraser
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Background Sepsis is a dysregulated systemic inflammatory response triggered by infection, resulting in organ dysfunction. A major challenge in clinical pediatrics is to identify sepsis early and then quickly intervene to reduce morbidity an
Externí odkaz:
https://doaj.org/article/f872daba81954849b4302323861ace37
Publikováno v:
Journal of Innate Immunity, Pp 1-14 (2021)
Regulation of proinflammatory cytokine expression is critical in the face of single-stranded RNA (ssRNA) virus infections. Many viruses, including coronavirus and influenza virus, wreak havoc on the control of cytokine expression, leading to the form
Externí odkaz:
https://doaj.org/article/2e088aacb02248b18bcf860afc08d504
Autor:
Kate McKenzie, Saoirse Cameron, Natalya Odoardi, Katelyn Gray, Michael R. Miller, Janice A. Tijssen
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundSurvival after pediatric out-of-hospital cardiac arrest is poor. Paramedic services provide critical interventions that impact survival outcomes. We aimed to describe local pediatric out-of-hospital cardiac arrest (POHCA) events and evaluat
Externí odkaz:
https://doaj.org/article/c7893b236d564988b250242c5cc08385
Autor:
Douglas D. Fraser, MD, PhD, Gediminas Cepinskas, DVM, PhD, Marat Slessarev, MD, MSc, Claudio M. Martin, MD, MSc, Mark Daley, PhD, Maitray A. Patel, BSc, Michael R. Miller, PhD, Eric K. Patterson, PhD, David B. O’Gorman, PhD, Sean E. Gill, PhD, Susanne Oehler, PhD, Markus Miholits, MSc, Brian Webb, PhD, on behalf of the Lawson COVID-19 Study Team, Robert Arntfield, Ian Ball, Gordon Barkwell, Tracey Bentall, Karen Bosma, Saoirse Cameron, Eileen Campbell, David Carter, Carolina Gillio-Meina, Robert Hegele, Natalya Odoardi, Ram Singh, Kelly Summers, Sue Tereschyn
Publikováno v:
Critical Care Explorations, Vol 3, Iss 3, p e0369 (2021)
Objectives:. Coronavirus disease 2019 continues to spread worldwide with high levels of morbidity and mortality. We performed anticoronavirus immunoglobulin G profiling of critically ill coronavirus disease 2019 patients to better define their underl
Externí odkaz:
https://doaj.org/article/b5452f32c170439fb320fdbdcd74f875
Autor:
Douglas D. Fraser, MD, PhD, Marat Slessarev, MD, MSc, Claudio M. Martin, MD, MSc, Mark Daley, PhD, Maitray A. Patel, BSc, Michael R. Miller, PhD, Eric K. Patterson, PhD, David B. O’Gorman, PhD, Sean E. Gill, PhD, David S. Wishart, PhD, Rupasri Mandal, PhD, Gediminas Cepinskas, DVM, PhD, On behalf of the Lawson COVID19 Study Team, Robert Arntfield, Ian Ball, Gordon Barkwell, Tracey Bentall, Karen Bosma, Saoirse Cameron, Eileen Campbell, David Carter, Carolina Gillio-Meina, Robert Hegele, Natalya Odoardi, Ram Singh, Kelly Summers, Sue Tereschyn
Publikováno v:
Critical Care Explorations, Vol 2, Iss 10, p e0272 (2020)
Objectives:. Coronavirus disease 2019 continues to spread rapidly with high mortality. We performed metabolomics profiling of critically ill coronavirus disease 2019 patients to understand better the underlying pathologic processes and pathways, and
Externí odkaz:
https://doaj.org/article/92333079a27c4fa2a62af564d80294da
Autor:
Douglas D. Fraser, MD, PhD, Gediminas Cepinskas, DVM, PhD, Eric K. Patterson, PhD, Marat Slessarev, MD, MSc, Claudio Martin, MD, MSc, Mark Daley, PhD, Maitray A. Patel, BSc, Michael R. Miller, PhD, David B. O’Gorman, PhD, Sean E. Gill, PhD, Guillaume Pare, MD, MSc, Ioannis Prassas, PhD, Eleftherios Diamandis, MD, PhD, on behalf of the Lawson COVID19 Study Team, Robert Arntfield, Ian Ball, Gordon Barkwell, Tracey Bentall, Karen Bosma, Saoirse Cameron, Eileen Campbell, David Carter, Carolina Gillio-Meina, Robert Hegele, Natalya Odoardi, Ram Singh, Kelly Summers, Sue Tereschyn
Publikováno v:
Critical Care Explorations, Vol 2, Iss 9, p e0189 (2020)
Objectives:. Coronavirus disease 2019 patients admitted to the ICU have high mortality. The host response to coronavirus disease 2019 has only been partially elucidated, and prognostic biomarkers have not been identified. We performed targeted proteo
Externí odkaz:
https://doaj.org/article/cccc0cb28a5d481eb92f663806d7c95a
Autor:
Douglas D. Fraser, MD, PhD, Eric K. Patterson, PhD, Marat Slessarev, MD, MSc, Sean E. Gill, PhD, Claudio Martin, MD, MSc, Mark Daley, PhD, Michael R. Miller, PhD, Maitray A. Patel, BSc, Claudia C. dos Santos, MD, MSc, Karen J. Bosma, MD, David B. O’Gorman, PhD, Gediminas Cepinskas, DVM, PhD, on behalf of the Lawson COVID19 Study Team, Robert Arntfield, Ian Ball, Gordon Barkwell, Tracey Bentall, Karen Bosma, Saoirse Cameron, Eileen Campbell, David Carter, Carolina Gillio-Meina, Robert Hegele, Natalya Odoardi, Ram Singh, Kelly Summers, Sue Tereschyn
Publikováno v:
Critical Care Explorations, Vol 2, Iss 9, p e0194 (2020)
Objectives:. Coronavirus disease 2019 is caused by the novel severe acute respiratory syndrome coronavirus 2 virus. Patients admitted to the ICU suffer from microvascular thrombosis, which may contribute to mortality. Our aim was to profile plasma th
Externí odkaz:
https://doaj.org/article/b201f1567225428ab5d1671023780bbd
Autor:
Douglas D. Fraser, MD, PhD, Gediminas Cepinskas, DVM, PhD, Marat Slessarev, MD, MSc, Claudio Martin, MD, MSc, Mark Daley, PhD, Michael R. Miller, PhD, David B. O’Gorman, PhD, Sean E. Gill, PhD, Eric K. Patterson, PhD, Claudia C. dos Santos, MD, MSc, on behalf of the Lawson COVID-19 Study Team, Robert Arntfield, Ian Ball, Gordon Barkwell, Tracey Bentall, Karen Bosma, Saoirse Cameron, Eileen Campbell, David Carter, Carolina Gillio-Meina, Robert Hegele, Natalya Odoardi, Ram Singh, Kelly Summers, Sue Tereschyn
Publikováno v:
Critical Care Explorations, Vol 2, Iss 6, p e0144 (2020)
Objectives:. Coronavirus disease 2019 is caused by severe acute respiratory syndrome-coronavirus-2 infection to which there is no community immunity. Patients admitted to ICUs have high mortality, with only supportive therapies available. Our aim was
Externí odkaz:
https://doaj.org/article/2e2aee660c2348e2bff3b3144f7398a4
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The role of the immune system in anti-tumor immunity cannot be overstated, as it holds the potential to promote tumor eradication or prevent tumor cell escape. Cytokines are critical to influencing the immune responses and interactions with non-immun
Externí odkaz:
https://doaj.org/article/260fb9bd7abf44e9bbf0732b190f0f9d
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Toll-like receptor (TLR)-7 is an endosomal innate immune sensor capable of detecting single-stranded ribonucleic acid. TLR7-mediated induction of type I interferon and other inflammatory cytokine production is important in antiviral immune responses.
Externí odkaz:
https://doaj.org/article/7b044a263a8a4b2bb3394e3d5a9bb8f1