Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Natalya Leneva"'
Autor:
Yann Gambin, Nicholas Ariotti, Kerrie-Ann McMahon, Michele Bastiani, Emma Sierecki, Oleksiy Kovtun, Mark E Polinkovsky, Astrid Magenau, WooRam Jung, Satomi Okano, Yong Zhou, Natalya Leneva, Sergey Mureev, Wayne Johnston, Katharina Gaus, John F Hancock, Brett M Collins, Kirill Alexandrov, Robert G Parton
Publikováno v:
eLife, Vol 3 (2014)
In mammalian cells three closely related cavin proteins cooperate with the scaffolding protein caveolin to form membrane invaginations known as caveolae. Here we have developed a novel single-molecule fluorescence approach to directly observe interac
Externí odkaz:
https://doaj.org/article/3222892030ff4bd78593681b9cee2d10
Autor:
Amy Kendall, Zhe Yang, Yi Cui, David A. Stroud, Robert G. Parton, Ryan J. Hall, Toby Passioura, Rajesh Ghai, Robert Reid, Timothy A. Hill, Boyang Xie, Joanna Sacharz, Suzanne J. Norwood, Michael D. Healy, Natalya Leneva, David P. Fairlie, Rohan D. Teasdale, Qian Guo, Sachini Fonseka, Kai-En Chen, Hiroaki Suga, Lauren P. Jackson, Brett M. Collins
Publikováno v:
Science Advances
Description
Novel macrocyclic peptides are found that bind and modulate the function of the retromer membrane trafficking complex.
The retromer complex (Vps35-Vps26-Vps29) is essential for endosomal membrane trafficking and signaling. Mutat
Novel macrocyclic peptides are found that bind and modulate the function of the retromer membrane trafficking complex.
The retromer complex (Vps35-Vps26-Vps29) is essential for endosomal membrane trafficking and signaling. Mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bad1a951f22f51ed878b0d84d5eba63
https://doi.org/10.1126/sciadv.abg4007
https://doi.org/10.1126/sciadv.abg4007
Publikováno v:
Science Advances
Retromer is a master regulator of cargo retrieval from endosomes, which is critical for many cellular processes including signalling, immunity, neuroprotection and virus infection. To function in different trafficking routes, retromer core (VPS26/VPS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9136190715528f7602743fc375428c
https://doi.org/10.1126/sciadv.abf8598
https://doi.org/10.1126/sciadv.abf8598
Autor:
Toby Passioura, Ryan J. Hall, Rohan D. Teasdale, Brett M. Collins, Amy Kendall, Yi Cui, Suzanne J. Norwood, Lauren P. Jackson, Hiroaki Suga, Zhe Yang, Boyang Xie, David P. Fairlie, Rajesh Ghai, Timothy A. Hill, Joanna Sacharz, Natalya Leneva, David A. Stroud, Kai-En Chen, Qian Guo
The Retromer complex (Vps35-Vps26-Vps29) is essential for endosomal membrane trafficking and signalling. Mutations in Retromer cause late-onset Parkinson’s disease, while viral and bacterial pathogens can hijack the complex during cellular infectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f02ce50fc604aed9f469987f315d037
https://doi.org/10.1101/2020.12.03.410779
https://doi.org/10.1101/2020.12.03.410779
Autor:
Rohan D. Teasdale, Yury S. Bykov, David J. Owen, Brett M. Collins, John A. G. Briggs, Miroslava Schaffer, Nicholas Ariotti, Benjamin D. Engel, Oleksiy Kovtun, Natalya Leneva
Publikováno v:
Nature. 561:561-564
Eukaryotic cells traffic proteins and lipids between different compartments using protein-coated vesicles and tubules. The retromer complex is required to generate cargo-selective tubulovesicular carriers from endosomal membranes1–3. Conserved in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32da2c5fc20f706610feb397028517e4
https://doi.org/10.1038/s41586-018-0526-z
https://doi.org/10.1038/s41586-018-0526-z
Autor:
Oleksiy, Kovtun, Natalya, Leneva, Yury S, Bykov, Nicholas, Ariotti, Rohan D, Teasdale, Miroslava, Schaffer, Benjamin D, Engel, David J, Owen, John A G, Briggs, Brett M, Collins
Publikováno v:
Nature. 561(7724)
Eukaryotic cells traffic proteins and lipids between different compartments using protein-coated vesicles and tubules. The retromer complex is required to generate cargo-selective tubulovesicular carriers from endosomal membranes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d150787d28fca2c9393b443b53b85206
https://pubmed.ncbi.nlm.nih.gov/30513333
https://pubmed.ncbi.nlm.nih.gov/30513333
Autor:
Wayne A. Johnston, Charles Ferguson, Nicholas Ariotti, Brett M. Collins, Natasha Chaudhary, Stephen J. Harrop, Vikas A. Tillu, WooRam Jung, Oleksiy Kovtun, Garry Morgan, Ramya A. Mandyam, Natalya Leneva, Robert G. Parton, Kirill Alexandrov
Publikováno v:
Developmental Cell. 31(4):405-419
SummaryCaveolae are cell-surface membrane invaginations that play critical roles in cellular processes including signaling and membrane homeostasis. The cavin proteins, in cooperation with caveolins, are essential for caveola formation. Here we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5da64b2425d7ad7bfdd1c730f5fbcec
Autor:
Natalya Leneva, Dominik Schwudke, Charles Ferguson, Kai Simons, Matthias Floetenmeyer, Richard I. Webb, Piers J. Walser, Leanne Cooper, Nicholas Ariotti, Ulf Skoglund, Kwang Jin Cho, Viola Oorschot, John F. Hancock, James Rae, Mark T. Howes, Robert G. Parton
Publikováno v:
Cell. 150:752-763
SummaryCaveolin plays an essential role in the formation of characteristic surface pits, caveolae, which cover the surface of many animal cells. The fundamental principles of caveola formation are only slowly emerging. Here we show that caveolin expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c43b7b20efeffba7fa71033dd09e565
https://doi.org/10.1016/j.cell.2012.06.042
https://doi.org/10.1016/j.cell.2012.06.042
Publikováno v:
Biochemistry (Moscow). 75:562-569
The ability of Pseudomonas fluorescens 26K strain to utilize naphthalene at concentrations up to 600 mg/liter as the sole source of carbon and energy in mineral liquid media was shown. Using HPLC, TLC, and mass-spectrometry, the intermediates of naph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aef7a85ca1fa5d4bdf00132fabe7c27
https://doi.org/10.1134/s0006297910050044
https://doi.org/10.1134/s0006297910050044
Publikováno v:
Applied Biochemistry and Microbiology. 45:169-175
The cells of Rhodococcus opacus 412 and R. rhodnii 135 were adapted to phenanthrene and anthracene on a solid mineral medium. Preliminary adaptation of the strains accelerated the metabolism of polyaromatic hydrocarbons and provided for the ability o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c152277d758750e05a669705fe6cc15
https://doi.org/10.1134/s0003683809020094
https://doi.org/10.1134/s0003683809020094