Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Natalya G. Dulyaninova"'
Autor:
Steven C. Almo, Kartik Chandran, Craig E. Cameron, Sean M. Cahill, Natalya G. Dulyaninova, J. Love, Jamie J. Arnold, Joyce Jose, Scott J. Garforth, Anne R. Bresnick, Quan Du, Tyler L. Grove, Rohit K. Jangra, Anthony S. Gizzi
Publikováno v:
Nature
Viral infections continue to represent major challenges to public health, and an enhanced mechanistic understanding of the processes that contribute to viral life cycles is necessary for the development of new therapeutic strategies1. Viperin, a memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae38d63251e53d7ac4c5f0e10219ffb
https://doi.org/10.1038/s41586-018-0238-4
https://doi.org/10.1038/s41586-018-0238-4
Autor:
Anthony S. Gizzi, Tyler L. Grove, Jamie J. Arnold, Joyce Jose, Rohit K. Jangra, Scott J. Garforth, Quan Du, Sean M. Cahill, Natalya G. Dulyaninova, James D. Love, Kartik Chandran, Anne R. Bresnick, Craig E. Cameron, Steven C. Almo
Publikováno v:
Nature. 583:E15-E15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dffa5948f29980814384fa3f38c8b1b1
https://doi.org/10.1038/s41586-020-2322-9
https://doi.org/10.1038/s41586-020-2322-9
Autor:
Jonathan M. Backer, Penelope D. Ruiz, Anne R. Bresnick, Matthew J. Gamble, Natalya G. Dulyaninova
Publikováno v:
Molecular biology of the cell. 29(5)
S100A4, a member of the S100 family of Ca2+-binding proteins, is a key regulator of cell migration and invasion. Our previous studies showed that bone marrow–derived macrophages from S100A4−/−mice exhibit defects in directional motility and che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915243357662ce8cb082790f480d4a53
https://pubmed.ncbi.nlm.nih.gov/29282275
https://pubmed.ncbi.nlm.nih.gov/29282275
Autor:
Natalya G. Dulyaninova, Steven C. Almo, Dominic A. Scudiero, Wendy D. Zencheck, Anne R. Bresnick, Karen M. Hite, Robert H. Shoemaker
Publikováno v:
Biochemistry. 50:7218-7227
Overexpression of S100A4, a member of the S100 family of Ca(2+)-binding proteins, is associated with a number of human pathologies, including fibrosis, inflammatory disorders, and metastatic disease. The identification of small molecules that disrupt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26a3c80d24f4d56a211f48d645ef85b
https://doi.org/10.1021/bi200853y
https://doi.org/10.1021/bi200853y
Publikováno v:
Molecular Biology of the Cell
Using a targeted genetic deletion, we show that the S100A4 metastasis factor is required for macrophage recruitment to sites of inflammation in vivo. S100A4−/− primary macrophages display defects in chemotaxis due to myosin-IIA overassembly and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4cf7d920d42d797e99427c9dea8952
https://doi.org/10.1091/mbc.e09-07-0609
https://doi.org/10.1091/mbc.e09-07-0609
Autor:
Jamie J. Arnold, Anthony S. Gizzi, Quan Du, Scott J. Garforth, Joyce Jose, Steven C. Almo, Tyler L. Grove, Kartik Chandran, Natalya G. Dulyaninova, Sean M. Cahill, Anne R. Bresnick, Rohit K. Jangra, Craig E. Cameron, J. Love
Publikováno v:
Nature. 562:E3-E3
Change history: In the HTML version of this Letter, Extended Data Fig. 4 incorrectly corresponded to Fig. 4 (the PDF version of the figure was correct). This has been corrected online.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::131d07bd941f6adf984fc93a46a3df6f
https://doi.org/10.1038/s41586-018-0355-0
https://doi.org/10.1038/s41586-018-0355-0
Publikováno v:
Cancer Research. 78:3168A-3168A
S100A4, a member of the S100 family of Ca2+-binding proteins, has a direct and causative role in tumor metastasis. In murine models of breast cancer, S100A4 overexpression in tumor cells promotes an aggressive metastatic phenotype, while inhibition o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::820301591315132f58af205d2159b9a3
https://doi.org/10.1158/1538-7445.am2018-3168a
https://doi.org/10.1158/1538-7445.am2018-3168a
Publikováno v:
Molecular Biology of the Cell. 20:338-347
To better understand the mechanism controlling nonmuscle myosin II (NM-II) assembly in mammalian cells, mutant NM-IIA constructs were created to allow tests in live cells of two widely studied models for filament assembly control. A GFP-NM-IIA constr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba3a24851a87c2999e0d2e0b2b905ab
https://doi.org/10.1091/mbc.e08-04-0372
https://doi.org/10.1091/mbc.e08-04-0372
Publikováno v:
Experimental Cell Research. 299:303-314
We have shown previously that the activity of the long myosin light chain kinase (MLCK) is cell cycle regulated with a decrease in specific activity during mitosis that can be restored following treatment with alkaline phosphatase. To better understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe840d7bb351f32a2b705732201aac67
https://doi.org/10.1016/j.yexcr.2004.06.015
https://doi.org/10.1016/j.yexcr.2004.06.015
Autor:
Naoki Mochizuki, Hisayoshi Yoshizaki, Anne R. Bresnick, Maria Carla Parrini, Michiyuki Matsuda, Yusuke Ohba, Natalya G. Dulyaninova
Publikováno v:
Journal of Biological Chemistry. 279:44756-44762
Rho family GTPases play pivotal roles in cytokinesis. By using probes based on the principle of fluorescence resonance energy transfer (FRET), we have shown that in HeLa cells RhoA activity increases with the progression of cytokinesis. Here we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c64bdb7b0c12fa418e38e11cac9dd73
https://doi.org/10.1074/jbc.m402292200
https://doi.org/10.1074/jbc.m402292200