Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Natalya G. Belogurova"'
Publikováno v:
Chemistry, Vol 5, Iss 3, Pp 1942-1960 (2023)
Here, we propose a drug delivery system for ciprofloxacin (CF) based on cyclodextrin (CD) polymer. We obtained a 3D matrix system with encapsulated drug molecules by crosslinking CF+CD non-covalent complexes with 1.6-hexamethylene isocyanate. The obt
Externí odkaz:
https://doaj.org/article/bf8815b220244b44a4b08d67b385fe36
Publikováno v:
Gels, Vol 10, Iss 9, p 567 (2024)
Rhodamine 6G (R6G) and 4-nitro-2,1,3-benzoxadiazole (NBD) linked through a spacer molecule spermidine (spd), R6G-spd-NBD, produces a fluorescent probe with pH-sensitive FRET (Förster (fluorescence) resonance energy transfer) effect that can be usefu
Externí odkaz:
https://doaj.org/article/f359d958e6354409a11d19b365db4410
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2353 (2023)
Bacterial infections are usually found in the stomach and the first part of the small intestine in association with various pathologies, including ulcers, inflammatory diseases, and sometimes cancer. Treatment options may include combinations of anti
Externí odkaz:
https://doaj.org/article/dbca2de0c598427599d4b44a6dc444ee
Autor:
Igor D. Zlotnikov, Maria P. Davydova, Milan R. Danilov, Sergey S. Krylov, Natalya G. Belogurova, Elena V. Kudryashova
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1102 (2023)
The drug resistance of pathogenic bacteria is often due efflux pumps—specific proteins that remove foreign compounds from bacterial cells. To overcome drug resistance, adjuvants are often used that can inhibit efflux pumps or other systems that ens
Externí odkaz:
https://doaj.org/article/d36481e58a7e48bea09f218f40a587cc
Autor:
Anna A. Skuredina, Linara R. Yakupova, Tatiana Yu. Kopnova, Irina M. Le-Deygen, Natalya G. Belogurova, Elena V. Kudryashova
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1598 (2023)
Respiratory infectious diseases have challenged medical communities and researchers. Ceftriaxone, meropenem and levofloxacin are widely used for bacterial infection treatment, although they possess severe side effects. To overcome this, we propose cy
Externí odkaz:
https://doaj.org/article/38860d0bf29c4f7d99251f32e425938d
Publikováno v:
Life, Vol 13, Iss 2, p 446 (2023)
Polymeric micelles combining the advantages of biocompatible poly- and oligosaccharides with classical micellar amphiphilic systems represent a promising class of drug carriers. In this work, micelles based on chitosan (or cyclodextrin) and oleic aci
Externí odkaz:
https://doaj.org/article/a9b502c92228441fb2a8d52cb97a1907
Autor:
Anna A. Skuredina, Tatiana Yu. Kopnova, Anastasia S. Tychinina, Sergey A. Golyshev, Irina M. Le-Deygen, Natalya G. Belogurova, Elena V. Kudryashova
Publikováno v:
Molecules, Vol 27, Iss 22, p 8026 (2022)
The new method of antibacterial-drug-activity investigation in vitro is proposed as a powerful strategy for understanding how carriers affect drug action during long periods (7 days). In this paper, we observed fluoroquinolone moxifloxacin (MF) antib
Externí odkaz:
https://doaj.org/article/fd42b5cbdcf449c59ca84882da406667
Autor:
Anna A. Skuredina, Anastasia S. Tychinina, Irina M. Le-Deygen, Sergey A. Golyshev, Tatiana Yu. Kopnova, Nikolay T. Le, Natalya G. Belogurova, Elena V. Kudryashova
Publikováno v:
Polymers, Vol 14, Iss 21, p 4476 (2022)
Cyclodextrins (CDs) are promising drug carriers that are used in medicine. We chose CDs with different substituents (polar/apolar, charged/neutral) to obtain polymers (CDpols) with different properties. CDpols are urethanes with average Mw of ~120 kD
Externí odkaz:
https://doaj.org/article/783eec2340f54993ad11f54fa6c7dac2
Autor:
Igor D. Zlotnikov, Alexander A. Ezhov, Rostislav A. Petrov, Maksim A. Vigovskiy, Olga A. Grigorieva, Natalya G. Belogurova, Elena V. Kudryashova
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1172 (2022)
Bacterial infections and especially resistant strains of pathogens localized in macrophages and granulomas are intractable diseases that pose a threat to millions of people. In this paper, the theoretical and experimental foundations for solving this
Externí odkaz:
https://doaj.org/article/acf8ff5ff2d84ff4af5e7430b526ff08
Autor:
Igor D. Zlotnikov, Natalya G. Belogurova, Sergey S. Krylov, Marina N. Semenova, Victor V. Semenov, Elena V. Kudryashova
Publikováno v:
Pharmaceuticals, Vol 15, Iss 7, p 861 (2022)
Allylpolyalkoxybenzenes (APABs) and terpenoids from plant essential oils exhibit a range of remarkable biological effects, including analgesic, antibacterial, anti-inflammatory, antioxidant, and others. Synergistic activity with antibiotics of differ
Externí odkaz:
https://doaj.org/article/cc80768d3563491f9d6a554a37893a2b