Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Natalya A. Ortolano"'
Autor:
Megan L. Rasmussen, Leigh A. Kline, Kyungho P. Park, Natalya A. Ortolano, Alejandra I. Romero-Morales, Christin C. Anthony, Kathryn E. Beckermann, Vivian Gama
Publikováno v:
Stem Cell Reports, Vol 10, Iss 3, Pp 684-692 (2018)
Summary: Human pluripotent stem cells (hPSCs) maintain a highly fragmented mitochondrial network, but the mechanisms regulating this phenotype remain unknown. Here, we describe a non-cell death function of the anti-apoptotic protein, MCL-1, in regula
Externí odkaz:
https://doaj.org/article/2df6637ac48c4d7f80179953171f6261
Autor:
Natalya A Ortolano, Alejandra I Romero-Morales, Megan L Rasmussen, Caroline Bodnya, Leigh A Kline, Piyush Joshi, Jon P Connelly, Kristie L Rose, Shondra M Pruett-Miller, Vivian Gama
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248000 (2021)
CUL9 is a non-canonical and poorly characterized member of the largest family of E3 ubiquitin ligases known as the Cullin RING ligases (CRLs). Most CRLs play a critical role in developmental processes, however, the role of CUL9 in neuronal developmen
Externí odkaz:
https://doaj.org/article/7d375e34c2ad4ce7b0be611c93c8e1b2
Autor:
Kyungho Park, Alejandra I. Romero-Morales, Vivian Gama, Leigh A. Kline, Megan L. Rasmussen, Kathryn E. Beckermann, Christin C. Anthony, Natalya A. Ortolano
Publikováno v:
Stem Cell Reports, Vol 10, Iss 3, Pp 684-692 (2018)
Stem Cell Reports
Stem Cell Reports
Summary Human pluripotent stem cells (hPSCs) maintain a highly fragmented mitochondrial network, but the mechanisms regulating this phenotype remain unknown. Here, we describe a non-cell death function of the anti-apoptotic protein, MCL-1, in regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5095a1cac1a7ce5335640db90f65e6e7
http://www.sciencedirect.com/science/article/pii/S2213671118300316
http://www.sciencedirect.com/science/article/pii/S2213671118300316
Publikováno v:
The Journal of Cell Biology
Romero-Morales et al. preview work from the Taniguchi et al. describing the role of a new structure, the apicosome, in lumenogenesis.
Establishment of apico–basal polarity is critical for the lumenal epiblast-like morphogenesis of human plurip
Establishment of apico–basal polarity is critical for the lumenal epiblast-like morphogenesis of human plurip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee2f5e7f6610082f7ec9ce61a1aef7e
http://europepmc.org/articles/PMC5716292
http://europepmc.org/articles/PMC5716292
Publikováno v:
Genes
Genes, Vol 9, Iss 2, p 109 (2018)
Genes, Vol 9, Iss 2, p 109 (2018)
The core transcriptional network regulating stem cell self-renewal and pluripotency remains an intense area of research. Increasing evidence indicates that modified regulation of basic cellular processes such as mitochondrial dynamics, apoptosis, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a8ac1d63c3f1f735df94c2228bc933
https://pubmed.ncbi.nlm.nih.gov/29463061
https://pubmed.ncbi.nlm.nih.gov/29463061
Autor:
Natalya A. Ortolano, Vivian Gama
Publikováno v:
Molecular cell. 66(3)
In this issue of Molecular Cell, Benvegnu et al. (2017) report an unexpected phenomenon by which the E3 ligase mahogunin ring finger-1 (MGRN1) translocates to the nucleus in an age-dependent manner, revealing an intriguing mechanism that allows for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e7ce06a590fe7a7b31857f44341cc5
https://pubmed.ncbi.nlm.nih.gov/28475865
https://pubmed.ncbi.nlm.nih.gov/28475865
Autor:
Yan-Lin Guo, Chandan Gurung, Vivian Gama, Dhiraj Acharya, Fengwei Bai, Natalya A. Ortolano, Bohan Chen, William A. D’Angelo
We reported previously that mouse embryonic stem cells do not have a functional IFN-based antiviral mechanism. The current study extends our investigation to the inflammatory response in mouse embryonic stem cells and mouse embryonic stem cell–diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8eebd152e82328802637dbfde9830d
https://europepmc.org/articles/PMC5321812/
https://europepmc.org/articles/PMC5321812/
