Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nataly Puerta-Cavanzo"'
Autor:
Ilke Sen, Xin Zhou, Alexey Chernobrovkin, Nataly Puerta-Cavanzo, Takaharu Kanno, Jérôme Salignon, Andrea Stoehr, Xin-Xuan Lin, Bora Baskaner, Simone Brandenburg, Camilla Björkegren, Roman A. Zubarev, Christian G. Riedel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The transcription factor DAF-16/FOXO mediates a wide variety of aging-preventive responses by driving the expression of stress resistance and longevity promoting genes. Here the authors show that transcriptional initiation at many DAF-16/FOXO target
Externí odkaz:
https://doaj.org/article/8a70884b9ec74e81afa962b134fef5ad
Autor:
Emilia Bigaeva, Nataly Puerta Cavanzo, Elisabeth G. D. Stribos, Amos J. de Jong, Carin Biel, Henricus A. M. Mutsaers, Michael S. Jensen, Rikke Nørregaard, Anna M. Leliveld, Igle J. de Jong, Jan-Luuk Hillebrands, Harry van Goor, Miriam Boersema, Ruud A. Bank, Peter Olinga
Publikováno v:
Pharmaceutics, Vol 12, Iss 5, p 459 (2020)
Animal models are a valuable tool in preclinical research. However, limited predictivity of human biological responses in the conventional models has stimulated the search for reliable preclinical tools that show translational robustness. Here, we us
Externí odkaz:
https://doaj.org/article/88f984b7474147c889380ff361af2440
Autor:
Nataly Puerta Cavanzo, Sophie A. Riesmeijer, Iris L. Holt-Kedde, Paul M. N. Werker, Bram Piersma, Peter Olinga, Ruud A. Bank
Publikováno v:
Scientific Reports, 12(1):13940. Nature Publishing Group
Dupuytren’s disease is a chronic, progressive fibroproliferative condition of the hand fascia which results in digital contraction. So far, treatments do not directly interfere with the (myo)fibroblasts that are responsible for the formation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69b33ff2348ac13743ba2718e8355d1
https://research.rug.nl/en/publications/9f10b3e6-86c4-4448-9468-79e5d380f8f4
https://research.rug.nl/en/publications/9f10b3e6-86c4-4448-9468-79e5d380f8f4
Publikováno v:
Frontiers in Medicine
Frontiers in Medicine, 7:615774. Frontiers Media S.A.
Frontiers in Medicine, Vol 7 (2021)
Frontiers in Medicine, 7:615774. Frontiers Media S.A.
Frontiers in Medicine, Vol 7 (2021)
An unsolved therapeutic problem in fibrosis is the overproduction of collagen. In order to screen the effect of anti-fibrotic drugs on collagen deposition, the Scar-in-a-Jar approach has been introduced about a decade ago. With macromolecular crowdin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf88dc6972b3d9b3de91bfd1f8b4af44
https://doi.org/10.3389/fmed.2020.615774
https://doi.org/10.3389/fmed.2020.615774
Autor:
Nataly Puerta Cavanzo
Fibrosis is involved in approximately 45% of all deaths in developed countries and available pharmacological treatments are scarce, if at all. Fibrosis is the result of a chronic pathological tissue repair process which can affect different organs of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5e103e9ea82a605dec00c836b3ca54
https://doi.org/10.33612/diss.190707273
https://doi.org/10.33612/diss.190707273
Autor:
Michael Schou Jensen, Igle J. de Jong, Nataly Puerta Cavanzo, Elisabeth G. D. Stribos, Harry van Goor, Carin Biel, Rikke Nørregaard, Ruud A. Bank, Emilia Bigaeva, Jan-Luuk Hillebrands, Amos J de Jong, Anna M. Leliveld, Miriam Boersema, Henricus A. M. Mutsaers, Peter Olinga
Publikováno v:
Pharmaceutics
Volume 12
Issue 5
Pharmaceutics, 12(5):459. MDPI AG
Pharmaceutics, Vol 12, Iss 459, p 459 (2020)
Bigaeva, E, Cavanzo, N P, Stribos, E G D, de Jong, A J, Biel, C, Mutsaers, H A M, Jensen, M S, Nørregaard, R, Leliveld, A M, de Jong, I J, Hillebrands, J L, van Goor, H, Boersema, M, Bank, R A & Olinga, P 2020, ' Predictive value of precision-cut kidney slices as an ex vivo screening platform for therapeutics in human renal fibrosis ', Pharmaceutics, vol. 12, no. 5, 459 . https://doi.org/10.3390/pharmaceutics12050459
Volume 12
Issue 5
Pharmaceutics, 12(5):459. MDPI AG
Pharmaceutics, Vol 12, Iss 459, p 459 (2020)
Bigaeva, E, Cavanzo, N P, Stribos, E G D, de Jong, A J, Biel, C, Mutsaers, H A M, Jensen, M S, Nørregaard, R, Leliveld, A M, de Jong, I J, Hillebrands, J L, van Goor, H, Boersema, M, Bank, R A & Olinga, P 2020, ' Predictive value of precision-cut kidney slices as an ex vivo screening platform for therapeutics in human renal fibrosis ', Pharmaceutics, vol. 12, no. 5, 459 . https://doi.org/10.3390/pharmaceutics12050459
Animal models are a valuable tool in preclinical research. However, limited predictivity of human biological responses in the conventional models has stimulated the search for reliable preclinical tools that show translational robustness. Here, we us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d279ee50d6e7acca82d46bdfbafbdc8e
https://doi.org/10.3390/pharmaceutics12050459
https://doi.org/10.3390/pharmaceutics12050459
Publikováno v:
Frontiers in Medicine, Vol 7 (2021)
An unsolved therapeutic problem in fibrosis is the overproduction of collagen. In order to screen the effect of anti-fibrotic drugs on collagen deposition, the Scar-in-a-Jar approach has been introduced about a decade ago. With macromolecular crowdin
Externí odkaz:
https://doaj.org/article/b26db37c766342768d57a216cf62e413