Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Nataly Naser AL Deen"'
Autor:
Yige Wu, Nadezhda V. Terekhanova, Wagma Caravan, Nataly Naser Al Deen, Preet Lal, Siqi Chen, Chia-Kuei Mo, Song Cao, Yize Li, Alla Karpova, Ruiyang Liu, Yanyan Zhao, Andrew Shinkle, Ilya Strunilin, Cody Weimholt, Kazuhito Sato, Lijun Yao, Mamatha Serasanambati, Xiaolu Yang, Matthew Wyczalkowski, Houxiang Zhu, Daniel Cui Zhou, Reyka G. Jayasinghe, Daniel Mendez, Michael C. Wendl, David Clark, Chelsea Newton, Yijun Ruan, Melissa A. Reimers, Russell K. Pachynski, Chris Kinsinger, Scott Jewell, Daniel W. Chan, Hui Zhang, Aadel A. Chaudhuri, Milan G. Chheda, Benjamin D. Humphreys, Mehdi Mesri, Henry Rodriguez, James J. Hsieh, Li Ding, Feng Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-25 (2023)
Abstract Identifying tumor-cell-specific markers and elucidating their epigenetic regulation and spatial heterogeneity provides mechanistic insights into cancer etiology. Here, we perform snRNA-seq and snATAC-seq in 34 and 28 human clear cell renal c
Externí odkaz:
https://doaj.org/article/f1e225c958cf48d29abdb4ad3857630a
Autor:
Nataly Naser Al Deen, Nadia Atallah Lanman, Shirisha Chittiboyina, Sabreen Fostok, Rihab Nasr, Sophie Lelièvre, Rabih Talhouk
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract microRNAs (miRNAs) serve as novel noninvasive cancer biomarkers. In an HMT-3522 S1 (S1) breast epithelial risk-progression three-dimensional (3D) culture model, non-neoplastic S1 cells form a fully polarized epithelium. When silenced for the
Externí odkaz:
https://doaj.org/article/5dfe4913a9ec4b00a3c6a0ad101792e9
Autor:
Yige Wu, Nadezhda V. Terekhanova, Wagma Caravan, Nataly Naser Al Deen, Preet Lal, Siqi Chen, Chia-Kuei Mo, Song Cao, Yize Li, Alla Karpova, Ruiyang Liu, Yanyan Zhao, Andrew Shinkle, Ilya Strunilin, Cody Weimholt, Kazuhito Sato, Lijun Yao, Mamatha Serasanambati, Xiaolu Yang, Matthew Wyczalkowski, Houxiang Zhu, Daniel Cui Zhou, Reyka G. Jayasinghe, Daniel Mendez, Michael C. Wendl, David Clark, Chelsea Newton, Yijun Ruan, Melissa A. Reimers, Russell K. Pachynski, Chris Kinsinger, Scott Jewell, Daniel W. Chan, Hui Zhang, Aadel A. Chaudhuri, Milan G. Chheda, Benjamin D. Humphreys, Mehdi Mesri, Henry Rodriguez, James J. Hsieh, Li Ding, Feng Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/fd169da4eccd46d28f702fba89461d95
Autor:
Nataly Naser Al Deen, Nadia Atallah Lanman, Shirisha Chittiboyina, Sophie Lelièvre, Rihab Nasr, Farah Nassar, Heinrich Zu Dohna, Mounir AbouHaidar, Rabih Talhouk
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract mRNA-circRNA-miRNAs axes have been characterized in breast cancer, but not as risk-assessment axes for tumor initiation in early-onset breast cancer that is increasing drastically worldwide. To address this gap, we performed circular RNA (ci
Externí odkaz:
https://doaj.org/article/894b1e32751742efa7e3f69f67100cba
Publikováno v:
International Journal of Inflammation, Vol 2021 (2021)
Inflammation is associated with the development of several cancers, including breast cancer. However, the molecular mechanisms driving breast cancer initiation or enhancement by inflammation are yet to be deciphered. Hence, we opted to investigate th
Externí odkaz:
https://doaj.org/article/b65f0f91f3ec4fc9806d2013a104a7ce
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Breast cancer (BC) is a global public health burden, constituting the highest cancer incidence in women worldwide. Connexin43 (Cx43) is a member of a family of transmembrane proteins responsible in part for intercellular communication between adjacen
Externí odkaz:
https://doaj.org/article/7297356e49f5431297a7a11a680a5785
Autor:
Mike Kareh, Rana El Nahas, Lamis Al-Aaraj, Sara Al-Ghadban, Nataly Naser Al Deen, Najat Saliba, Marwan El-Sabban, Rabih Talhouk
Publikováno v:
SAGE Open Medicine, Vol 6 (2018)
Objective: Sea cucumbers are considered among the most important functional foods. Following bioassay guided fractionation, we assessed the anti-proliferative and anti-inflammatory activities of Holothuria polii ( H. polii ) extracts. Methods: Sea cu
Externí odkaz:
https://doaj.org/article/07fb4c50ac7a4b658959a08d09f17769
Autor:
Nataly Naser Al Deen, Katie M. Campbell, Egmidio Medina, Cynthia R. Gonzalez, Philip O. Scumpia, Antoni Ribas
Publikováno v:
Cancer Research. 83:4532-4532
Background: Immune checkpoint blockade (ICB) therapies promote anti-tumor activity by facilitating CD8 T-cell activation at the tumor site (e.g., anti-PD-1), or in the lymph node, promoting T-cells trafficking to the tumor site (e.g., anti-CTLA-4). F
WU sn-prep Protocol for Solid Tumors -snRNA protocol v2.7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d935ccf06ee9f27856e84d9b1d9eb35
https://doi.org/10.17504/protocols.io.b72jrqcn
https://doi.org/10.17504/protocols.io.b72jrqcn
Autor:
Chia-Kuei Mo, Yige Wu, Terekhanova Nadezhda, Caravan Wagma, Preet Lal, Siqi Chen, Nataly Naser AL Deen, Ruiyang Liu, Yanyan Zhao, Kazuhito Sato, Lijun Yao, Mamatha Serasanambati, Andrew Shinkle, Reyka G. Jayasinghe, Li Ding, Feng Chen
Publikováno v:
Cancer Research. 82:2025-2025
Next-generation sequencing enabled molecular landscaping and the discovery of novel tumor markers in ccRCC. However, the spatial relationships and histological features of the tumor microenvironment were lost during this process. Combining snRNA-seq,