Výsledky vyhledávání - "Natalja, Beying"

Double strand break (DSB) repair pathways in plants and their application in genome engineering

Autor: Natalja Beying, Carla Schmidt, Holger Puchta, Valerie Miller

Publikováno v: Genome editing for precision crop breeding ISBN: 9781786764478
Genome editing for precision crop breeding

In genome engineering, after targeted induction of double strand breaks (DSBs) researchers take advantage of the organisms’ own repair mechanisms to induce different kinds of sequence changes into the genome. Therefore, understanding of the underly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525c6867cd974205611a29ed4c69b565
https://doi.org/10.1201/9781003048237-3

Zobrazit plný text záznamu

Different DNA repair pathways are involved in single-strand break-induced genomic changes in plants

Autor: Patrick Schindele, Armin Scheben, Natalja Beying, Felix Wolter, Holger Puchta

Publikováno v: Plant Cell
Journal of Oncology
The plant cell, 33 (11), 3454–3469

In nature, single-strand breaks (SSBs) in DNA occur more frequently (by orders of magnitude) than double-strand breaks (DSBs). SSBs induced by the CRISPR/Cas9 nickase at a distance of 50–100 bp on opposite strands are highly mutagenic, leading to i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48fb638f9a43d5a4efb50e3dbe538563

Zobrazit plný text záznamu

CRISPR-Cas9-mediated induction of heritable chromosomal translocations in Arabidopsis

Autor: Natalja, Beying, Carla, Schmidt, Michael, Pacher, Andreas, Houben, Holger, Puchta

Publikováno v: Nature plants. 6(6)

Clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein (Cas) technology has been applied in plant breeding mainly on genes for improving single or multiple traits

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::21c4e9a382fa164fbeb0d2626731bdf8
https://pubmed.ncbi.nlm.nih.gov/32451450

Zobrazit plný text záznamu

CRISPR–Cas9-mediated induction of heritable chromosomal translocations in Arabidopsis

Autor: Carla Schmidt, Andreas Houben, Natalja Beying, Holger Puchta, Michael Pacher

Publikováno v: Nature Plants
Nature plants, 6, 638–645

Clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein (Cas) technology has been applied in plant breeding mainly on genes for improving single or multiple traits1–4. Here we show that this technology can als

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69e9c3f9429ccc77029a8c7b8f68e72

Zobrazit plný text záznamu

The protease WSS1A, the endonuclease MUS81 and the phosphodiesterase TDP1 are involved in independent pathways of DNA-protein crosslink repair in plants

Autor: Natalja Beying, Oliver Trapp, Holger Puchta, Janina Enderle, Annika Dorn

Publikováno v: The plant cell, 31 (4), 775-790
The Plant Cell

DNA–protein crosslinks (DPCs) represent a severe threat to the genome integrity; however, the main mechanisms of DPC repair were only recently elucidated in humans and yeast. Here we define the pathways for DPC repair in plants. Using CRISPR/Cas9,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf62a515961b55a3678fa7a420b0818

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání