Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nataliya I. Trushina"'
Autor:
Luca Pinzi, Christian Conze, Nicolo Bisi, Gabriele Dalla Torre, Ahmed Soliman, Nanci Monteiro-Abreu, Nataliya I. Trushina, Andrea Krusenbaum, Maryam Khodaei Dolouei, Andrea Hellwig, Michael S. Christodoulou, Daniele Passarella, Lidia Bakota, Giulio Rastelli, Roland Brandt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Tauopathies such as Alzheimer’s disease are characterized by aggregation and increased phosphorylation of the microtubule-associated protein tau. Tau’s pathological changes are closely linked to neurodegeneration, making tau a prime cand
Externí odkaz:
https://doaj.org/article/46bfa35f5bc64145adbe0445e00ba099
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Tau protein (MAPT) is classified as a microtubule-associated protein (MAP) and is believed to regulate the axonal microtubule arrangement. It belongs to the tau/MAP2/MAP4 family of MAPs that have a similar microtubule binding region at their carboxy-
Externí odkaz:
https://doaj.org/article/16e3e7e94d164cfca3fd08677604b32b
Autor:
Svyatoslav S. Sokolov, Margarita A. Vorobeva, Alexandra I. Smirnova, Ekaterina A. Smirnova, Nataliya I. Trushina, Kseniia V. Galkina, Fedor F. Severin, Dmitry A. Knorre
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Lam proteins transport sterols between the membranes of different cellular compartments. In Saccharomyces cerevisiae, the LAM gene family consists of three pairs of paralogs. Because the function of paralogous genes can be redundant, the phenotypes o
Externí odkaz:
https://doaj.org/article/054f6e9e2d3845c194739cf233fe43cb
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Tau is a neuronal microtubule-associated protein (MAP) that is involved in the regulation of axonal microtubule assembly. However, as a protein with intrinsically disordered regions (IDRs), tau also interacts with many other partners in addition to m
Externí odkaz:
https://doaj.org/article/f86da85bd06847a8a49a889724023edb
Publikováno v:
Brain Research Bulletin. 194:13-22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71045f3d399ff829f74d64838fa327e5
https://doi.org/10.1016/j.brainresbull.2022.12.012
https://doi.org/10.1016/j.brainresbull.2022.12.012
Autor:
Christian Conze, Marina Rierola, Nataliya I. Trushina, Michael Peters, Dennis Janning, Max Holzer, Jürgen J. Heinisch, Thomas Arendt, Lidia Bakota, Roland Brandt
Publikováno v:
Molecular Psychiatry. 27:3010-3023
The microtubule-associated protein tau plays a central role in tauopathies such as Alzheimer’s disease (AD). The exact molecular mechanisms underlying tau toxicity are unclear, but aging is irrefutably the biggest risk factor. This raises the quest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e81fdc8d2f1b7297fca40d5282b08cd9
https://doi.org/10.1038/s41380-022-01538-2
https://doi.org/10.1038/s41380-022-01538-2
Autor:
Luca Pinzi, Christian Conze, Nicolo Bisi, Gabriele Dalla Torre, Nanci Monteiro-Abreu, Nataliya I. Trushina, Ahmed Soliman, Andrea Krusenbaum, Maryam Khodaei Dolouei, Andrea Hellwig, Michael S. Christodoulou, Daniele Passarella, Lidia Bakota, Giulio Rastelli, Roland Brandt
Tauopathies such as Alzheimer’s disease are characterized by the aggregation and increased phosphorylation of the microtubule-associated protein tau. The pathological changes in tau are closely linked to neurodegeneration, making tau a prime candid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecf20f97aaeeac224a616e217be5c71f
https://doi.org/10.1101/2022.10.31.514565
https://doi.org/10.1101/2022.10.31.514565
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2428
Stress granules (SGs) are cytosolic, nonmembranous RNA-protein (RNP) complexes that form in the cytosol of many cells under various stress conditions and can integrate responses to various stressors. Although physiological SG formation appears to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1faeb9663eccfa0259be2b8d0a2648b
https://pubmed.ncbi.nlm.nih.gov/35171484
https://pubmed.ncbi.nlm.nih.gov/35171484
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619742
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87cb14e26120e6610b85419f6b8346a8
https://doi.org/10.1007/978-1-0716-1975-9_15
https://doi.org/10.1007/978-1-0716-1975-9_15
Publikováno v:
Biological Chemistry. 400:1163-1179
The evolution of a highly developed nervous system is mirrored by the ability of individual neurons to develop increased morphological complexity. As microtubules (MTs) are crucially involved in neuronal development, we tested the hypothesis that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4a4aef343db79558ee77c97ec92b75
https://doi.org/10.1515/hsz-2019-0149
https://doi.org/10.1515/hsz-2019-0149