Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Nataliya B. Petrenko"'
Autor:
Rebecca Windmueller, John P. Leach, Apoorva Babu, Su Zhou, Michael P. Morley, Aoi Wakabayashi, Nataliya B. Petrenko, Patrick Viatour, Edward E. Morrisey
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 3105-3116.e4 (2020)
Summary: The mammalian heart is incapable of regenerating a sufficient number of cardiomyocytes to ameliorate the loss of contractile muscle after acute myocardial injury. Several reports have demonstrated that mononucleated cardiomyocytes are more r
Externí odkaz:
https://doaj.org/article/4cc9d514ae934b469d3b2fc8c7e2809f
Autor:
John Leach, Michael Morley, Aoi Wakabayashi, Rebecca Windmueller, Apoorva Babu, Edward E. Morrisey, Nataliya B. Petrenko, Su Zhou, Patrick Viatour
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 3105-3116.e4 (2020)
Cell reports
Cell reports
SUMMARY The mammalian heart is incapable of regenerating a sufficient number of cardiomyocytes to ameliorate the loss of contractile muscle after acute myocardial injury. Several reports have demonstrated that mononucleated cardiomyocytes are more re
Autor:
Vickas V. Patel, Bastiaan J. Boukens, Nataliya B. Petrenko, Michael J. Rust, Ozanna Burnicka-Turek, Kohta Ikegami, Ivan P. Moskowitz, Igor R. Efimov, Marcelo A. Nobrega, Jeffrey D. Steimle, Michael Broman, Xinan Yang
Publikováno v:
Circulation Research. 127
The heart beats 2 billion times over the average human lifespan and is the manifestation of a pattern of cardiomyocyte depolarization organized by a specialized network of cardiomyocytes, the cardiac conduction system (CCS). Patterning of the CCS int
Autor:
Rangarajan D. Nadadur, Xinan Yang, Vickas V. Patel, David E. Arnolds, Bastiaan J. Boukens, Nataliya B. Petrenko, Michael Broman, Kohta Ikegami, Ivan P. Moskowitz, Igor R. Efimov, Ozanna Burnicka-Turek, Marcelo A. Nobrega, Yun Qiao, Jeffrey D. Steimle
Publikováno v:
Circ Res
Circulation research, 127(3), E94-E106. Lippincott Williams and Wilkins
Circulation research, 127(3), E94-E106. Lippincott Williams and Wilkins
Rationale: The heartbeat is organized by the cardiac conduction system (CCS), a specialized network of cardiomyocytes. Patterning of the CCS into atrial node versus ventricular conduction system (VCS) components with distinct physiology is essential
Autor:
J`unil Kim, Timothy Matsuura, Ling Lai, Kiran Musunuru, Christopher Petucci, Nataliya B. Petrenko, Kyoung-Jae Won, Daniel P. Kelly, Rick B. Vega, David M. Ryba, Shibiao Wan, Tomoya Sakamoto
Publikováno v:
Circulation research. 126(12)
Rationale: The heart undergoes dramatic developmental changes during the prenatal to postnatal transition, including maturation of cardiac myocyte energy metabolic and contractile machinery. Delineation of the mechanisms involved in cardiac postnatal
Autor:
Wenjun Li, Wenjian Lv, Kiran Musunuru, Chris McDermott-Roe, Anjali T. Owens, Nataliya B. Petrenko, Lyon Qiao
Publikováno v:
Circulation. 138(24)
Autor:
Kiran Musunuru, Lyon Qiao, Wenjian Lv, Chris McDermott-Roe, Anjali T. Owens, Nataliya B. Petrenko, Wenjun Li
Publikováno v:
Circulation Research. 123
The introduction of clinical sequencing is dramatically increasing the discovery of variants of uncertain significance (VUSs) in genes linked to inherited cardiomyopathies. We have established a platform for rapid and efficient insertion of TNNT2 gen
Autor:
Clara Franzini-Armstrong, Kristen Colavita, Nataliya B. Petrenko, Matias Escobar, César Cárdenas
Publikováno v:
Journal of Molecular and Cellular Cardiology. 50:451-459
At each heartbeat, cardiac myocytes are activated by a cytoplasmic Ca(2+) transient in great part due to Ca(2+) release from the sarcoplasmic reticulum via ryanodine receptors (RyRs) clustered within calcium release units (peripheral couplings/dyads)
Autor:
Vickas V. Patel, Kurt J. Schillinger, Hayoung Hwang, Nataliya B. Petrenko, Jianhe Huang, Fang Liu
Publikováno v:
Physiological Reports
Cardiac melanocyte-like cells (CMLCs) contribute to atrial arrhythmias when missing the melanin synthesis enzyme dopachrome tautomerase (Dct). While scavenging reactive oxygen species (ROS) in Dct-null mice partially suppressed atrial arrhythmias, it
Autor:
Edward E. Morrisey, Nataliya B. Petrenko, Deqiang Li, Tao Wang, Melinda Snitow, Kathleen M. Stewart, Michael Morley, Erhe Gao, Ying Liu, L.-Q. Chen, Ning Zhou, Jun Kong, Walter J. Koch, Su Zhou, Ying Tian, Minmin Lu
Publikováno v:
Science Translational Medicine. 7
In contrast to lower vertebrates, the mammalian heart has limited capacity to regenerate after injury in part due to ineffective reactivation of cardiomyocyte proliferation. We show that the microRNA cluster miR302-367 is important for cardiomyocyte