Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nataliia V. Krasnoperova"'
Autor:
Nataliia V. Krasnoperova, Suzhen Li, Xiao Hu, Monica L. Hultman, Sarah Du, Jessica D. Dietz, Dean Welsch, Deepak S. Lala, Chunsheng Xia
Publikováno v:
Molecular Endocrinology. 19:1460-1473
We investigated the coregulator (coactivator and corepressor) interactions with the mineralocorticoid receptor (MR) that lead to activation and inhibition of the receptor in the presence of agonist and/or antagonist. Our results indicate that MR liga
Autor:
Pamela Eversole-Cire, Charlotte E. Remé, Allen Taylor, Yelena Kleyner, Martin S. Obin, Christian Grimm, Wenshan Hao, Andreas Wenzel, Ching-Kang Chen, Melvin I. Simon, Elliott Brill, Janis Lem, Nataliia V. Krasnoperova
Publikováno v:
Nature Genetics. 32:254-260
Excessive phototransduction signaling is thought to be involved in light-induced and inherited retinal degeneration. Using knockout mice with defects in rhodopsin shut-off and transducin signaling, we show that two different pathways of photoreceptor
Autor:
Klaus Rüther, Jeanne M. Frederick, Wolfgang Baehr, Nataliia V. Krasnoperova, Kirstin Hoffmann, Janis Lem
Publikováno v:
Retinal Degenerative Diseases and Experimental Therapy ISBN: 9780306461934
The rod opsin Pro23His mutation accounts for approximately 12% of autosomal dominant retinitis pigmentosa (adRP) cases in the United States. To study mechanisms leading to photoreceptor degeneration, we investigated the effects of mutant and wild-typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2d62a882de215d19a580b2d5c709996
https://doi.org/10.1007/978-0-585-33172-0_10
https://doi.org/10.1007/978-0-585-33172-0_10
Autor:
Clint L. Makino, Massimo Nicolò, Janis Lem, Nataliia V. Krasnoperova, Bela Kosaras, Peter D. Calvert, Richard L. Sidman, David A. Cameron
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 96(2)
Mutations in rod opsin, the visual pigment protein of rod photoreceptors, account for approximately 15% of all inherited human retinal degenerations. However, the physiological and molecular events underlying the disease process are not well understo