Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Natalie YL. Ngoi"'
Autor:
Natalie YL. Ngoi, Angeline QX. Liew, Stephen J.F. Chong, Matthew S. Davids, Marie-Veronique Clement, Shazib Pervaiz
Publikováno v:
Redox Biology, Vol 45, Iss , Pp 102032- (2021)
Significance: Cellular growth arrest, associated with ‘senescence’, helps to safeguard against the accumulation of DNA damage which is often recognized as the underlying mechanism of a wide variety of age-related pathologies including cancer. Cel
Externí odkaz:
https://doaj.org/article/5a1719c737be483290b40800494bdf5e
Autor:
Yoo-Na Kim, Boram Park, Jae Weon Kim, Byoung Gie Kim, Sang Wun Kim, Hee Seung Kim, Chel Hun Choi, Myong Cheol Lim, Natalie YL Ngoi, David SP Tan, Jung-Yun Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract In this multicenter, open-label, single-arm, Phase II study with Simon two-stage optimum design (NCT04361370), we investigate the efficacy and safety of triplet maintenance (olaparib, pembrolizumab, bevacizumab) in patients with platinum-sen
Externí odkaz:
https://doaj.org/article/1de04bd62c64433c9bfbae88ccacfbad
Autor:
Natalie YL Ngoi, Nicholas LX Syn, Robby M Goh, Boon Cher Goh, Ruby Yun-Ju Huang, Yu Yang Soon, Elizabeth James, Adrian Cook, Andrew Clamp, David SP Tan
Publikováno v:
Cochrane Database Syst Rev
BACKGROUND: Epithelial ovarian cancer is the sixth most common cancer worldwide: 295,414 new cases were diagnosed in 2018, with 184,799 deaths. The lack of an effective screening strategy has led to the majority of women being diagnosed at an advance
Autor:
YunSoo Chung, Yoo-Na Kim, Boram Park, Jae weon Kim, Byoung Gie Kim, Sang Wun Kim, Hee Seung Kim, Chel Hun Choi, Myong Cheol Lim, Natalie Yl Ngoi, David Sp Tan, Jung-Yun Lee
Publikováno v:
Proceedings of the 38th Annual Meeting of Korean Society of Gynecologic Oncology.
Publikováno v:
International Journal of Gynecologic Cancer. 32:246-259
The management of advanced cervical cancer has evolved with time. Combined modality treatments for cervical cancer have been shown to improve clinical outcomes for these patients. The role of surgery is reviewed in this article for specific situation
Publikováno v:
Best Practice & Research Clinical Obstetrics & Gynaecology. 78:14-35
The adjuvant and post-surgical treatment of gynaecological cancers has historically been guided by the estimation of relapse risk based on clinicopathological factors determined at the time of cancer diagnosis. The recent advancement of genomic and m
Autor:
Yasushi Iida, Mitsutake Yano, Natalie Yl Ngoi, David S.P. Tan, C. Simon Herrington, Aikou Okamoto, Maiko Miwa, Diana Lim, Sb Justin Wong, Valerie Heong, Jieru Ye, Charlie Gourley, Masanori Yasuda, Tuan Zea Tan, Ruby Yj Huang, Kosei Hasegawa
Publikováno v:
Heong, V, Tan, T Z, Miwa, M, Ye, J, Lim, D, Herrington, C S, Iida, Y, Yano, M, Yasuda, M, Ngoi, N Y, Wong, S J, Okamoto, A, Gourley, C, Hasegawa, K, Tan, D S & Huang, R Y 2021, ' A multi-ethnic analysis of immune-related gene expression signatures in patients with ovarian clear cell carcinoma ', The Journal of Pathology . https://doi.org/10.1002/path.5769
Little is known about the immune environment of ovarian clear cell carcinoma (OCCC) and its impact on various ethnic backgrounds. The aim of this OCCC immune-related gene expression signatures (irGES) study was to address the interaction between tumo
Autor:
Yoo-Na Kim, Boram Park, Jae-Weon Kim, Byoung-Gie Kim, Sang Wun Kim, Hee Seung Kim, Chel Hun Choi, Myong Cheol Lim, Natalie Yl Ngoi, David Sp Tan, Jung-Yun Lee
Publikováno v:
SSRN Electronic Journal.
Autor:
Natalie Yl Ngoi, Yvonne Le Ang, Yiqing Huang, Wan Qin Chong, Ross A. Soo, Gloria Chan, Joan Re Choo, Zhi Yao Chan, Alvin Wong, Vaishnavi Muthu, Jia Li Low, Yong Xiang Gwee
Publikováno v:
Lung Cancer. 146:145-153
Background The importance of immune-checkpoint inhibitors (ICI) can no longer be understated since its move to front-line treatment in non-small cell lung cancer (NSCLC) in recent years. However, the safety and efficacy of ICI in special populations
Publikováno v:
International Journal of Gynecological Cancer
Elevated levels of replicative stress in gynecological cancers arising from uncontrolled oncogenic activation, loss of key tumor suppressors, and frequent defects in the DNA repair machinery are an intrinsic vulnerability for therapeutic exploitation