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Autor:
Charles E. de Bock, Matthew D. Dun, Elham Sadeqzadeh, Janet E. Holt, Natalie Wojtalewicz, Irmgard Schwarte-Waldhoff, Nathan D. Smith, Rick F. Thorne
Publikováno v:
Experimental Cell Research. 323:41-55
Fat1 is a single pass transmembrane protein and the largest member of the cadherin superfamily. Mouse knockout models and in vitro studies have suggested that Fat1 influences cell polarity and motility. Fat1 is also an upstream regulator of the Hippo