Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Natalie Tschorn"'
Autor:
Alina Hengelbrock, Finja Probst, Simon Baukmann, Alexander Uhl, Natalie Tschorn, Jörn Stitz, Axel Schmidt, Jochen Strube
Publikováno v:
ACS Omega, Vol 9, Iss 32, Pp 34990-35013 (2024)
Externí odkaz:
https://doaj.org/article/10197cf5d9db46619d23d5a1ae6d9db4
Autor:
Yasemin van Heuvel, Stefanie Schatz, Marc Hein, Tanya Dogra, Daniel Kazenmaier, Natalie Tschorn, Yvonne Genzel, Jörn Stitz
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
To date, the establishment of high-titer stable viral packaging cells (VPCs) at large scale for gene therapeutic applications is very time- and cost-intensive. Here we report the establishment of three human suspension 293-F-derived ecotropic MLV-bas
Externí odkaz:
https://doaj.org/article/8c77412358714224822d96c752627bca
Publikováno v:
Molecular biotechnology.
The use of two-component transposon plasmid vector systems, namely, a transposase construct and a donor vector carrying the gene of interest (GOI) can accelerate the development of recombinant cell lines. However, the undesired stable transfection of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36d6331358bb5a5e6993ec942292447
https://pubmed.ncbi.nlm.nih.gov/36547824
https://pubmed.ncbi.nlm.nih.gov/36547824
Publikováno v:
Virology. 577
Viral vectors derived from human immunodeficiency virus type 1 (HIV-1) mediate efficient stable gene transduction. Consequently, these vectors are utilized in gene therapeutic approaches. We here aimed for improving HIV-1 pseudotype vector formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98a55309f9a1d34ba542940e821e051
https://pubmed.ncbi.nlm.nih.gov/36343471
https://pubmed.ncbi.nlm.nih.gov/36343471
Publikováno v:
Biotechnology Letters
Stable recombinant mammalian cells are of growing importance in pharmaceutical biotechnology production scenarios for biologics such as monoclonal antibodies, growth and blood factors, cytokines and subunit vaccines. However, the establishment of rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1bac11a565a5f2263361510435d28c
https://doi.org/10.1007/s10529-020-02889-y
https://doi.org/10.1007/s10529-020-02889-y
Publikováno v:
Methods in Molecular Biology ISBN: 9781493998524
Stable mammalian, namely human, suspension cell lines play a pivotal role in red biotechnology production scenarios for the generation of state-of-the-art biologics. However, selection of genetically modified and highly productive cell populations -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::630c53af6c43955c33b967f22feb4b01
https://doi.org/10.1007/978-1-4939-9853-1_20
https://doi.org/10.1007/978-1-4939-9853-1_20
