Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Natalie Tigue"'
Autor:
Thomas V. Murray, Kasia Kozakowska-McDonnell, Adam Tibbles, Annabel Taylor, Daniel Higazi, Emmanuel Rossy, Alessandra Rossi, Sivaneswary Genapathy, Giulia Tamburrino, Nicola Rath, Natalie Tigue, Vivian Lindo, Tristan Vaughan, Monika A. Papworth
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Bioconjugates are an important class of therapeutic molecules. To date, O-glycan-based metabolic glycoengineering has had limited use in this field, due to the complexities of the endogenous O-glycosylation pathway and the lack of an O-glycosylation
Externí odkaz:
https://doaj.org/article/cf1665fccfe940a89c94acdca72f40c1
Autor:
Jackie Cheng, Meina Liang, Miguel F. Carvalho, Natalie Tigue, Raffaella Faggioni, Lorin K. Roskos, Inna Vainshtein
Publikováno v:
Antibodies, Vol 9, Iss 3, p 49 (2020)
Amplification and overexpression of HER2 (human epidermal growth factor receptor 2), an ErbB2 receptor tyrosine kinase, have been implicated in human cancer and metastasis. A bispecific tetravalent anti-HER2 antibody (anti-HER2-Bs), targeting two non
Externí odkaz:
https://doaj.org/article/d23b66fb5b1140e39792ceb15857ee05
Autor:
Luisa Statello, Marco Maugeri, Elena Garre, Muhammad Nawaz, Jessica Wahlgren, Alexandros Papadimitriou, Christina Lundqvist, Lennart Lindfors, Anna Collén, Per Sunnerhagen, Marco Ragusa, Michele Purrello, Cinzia Di Pietro, Natalie Tigue, Hadi Valadi
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195969 (2018)
The RNA that is packaged into exosomes is termed as exosomal-shuttle RNA (esRNA); however, the players, which take this subset of RNA (esRNA) into exosomes, remain largely unknown. We hypothesized that RNA binding proteins (RBPs) could serve as key p
Externí odkaz:
https://doaj.org/article/b2cf47c08cfc43138c14c6816952d28f
Autor:
Abigail J. Smith, Elise A. Naudin, Caitlin L. Edgell, Emily G. Baker, Bram Mylemans, Laura FitzPatrick, Andrew Herman, Helen M. Rice, David M. Andrews, Natalie Tigue, Derek N. Woolfson, Nigel J. Savery
Publikováno v:
ACS Synthetic Biology.
Autor:
Stacey Chin, Christina Schindler, Lisa Vinall, Roger Dodd, Lisa Bamber, Sandrine Legg, Anna Sigurdardottir, D. Rees, Tim Malcolm, Samantha Spratley, Natalie Tigue
Chemical inducer of dimerization (CID) modules can be used effectively as molecular switches to control biological processes, and thus there is significant interest within the synthetic biology community in identifying novel CID systems. To date, CID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c137b243a16d52f270a397ca20c88eea
https://doi.org/10.21203/rs.3.rs-2244031/v1
https://doi.org/10.21203/rs.3.rs-2244031/v1
Autor:
Elise A. Naudin, Katherine I. Albanese, Abigail J. Smith, Bram Mylemans, Emily G. Baker, Orion D. Weiner, David M. Andrews, Natalie Tigue, Nigel J. Savery, Derek N. Woolfson
Publikováno v:
Naudin, E A, Albanese, K I, Smith, A J, Mylemans, B, Baker, E G, Savery, N J, Woolfson, D N & et, A 2022, ' From peptides to proteins : coiled-coil tetramers to single-chain 4-helix bundles ', Chemical Science, vol. 13, no. 38, pp. 11330-11340 . https://doi.org/10.1039/D2SC04479J
The design of completely synthetic proteins from first principles—de novo protein design—is challenging. This is because, despite recent advances in computational protein-structure prediction and design, we do not understand fully the sequence-to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49de030d354e6b82f0d5fa2d6401d9fd
https://doi.org/10.1101/2022.08.04.502660
https://doi.org/10.1101/2022.08.04.502660
Autor:
Jennifer, Spooner, Jenny, Keen, Kalpana, Nayyar, Neil, Birkett, Nicholas, Bond, David, Bannister, Natalie, Tigue, Daniel, Higazi, Benjamin, Kemp, Tristan, Vaughan, Alistair, Kippen, Andrew, Buchanan
Publikováno v:
Biotechnology and bioengineering. 112(7)
Fabs are an important class of antibody fragment as both research reagents and therapeutic agents. There are a plethora of methods described for their recombinant expression and purification. However, these do not address the issue of excessive light