Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Natalie Telis"'
Combining rare and common genetic variants improves population risk stratification for breast cancer
Autor:
Alexandre Bolze, Daniel Kiser, Kelly M. Schiabor Barrett, Gai Elhanan, Jamie M. Schnell Blitstein, Iva Neveux, Shaun Dabe, Harry Reed, Alexa Anderson, William J. Metcalf, Ekaterina Orlova, Ildiko Thibodeau, Natalie Telis, Ruomu Jiang, Nicole L. Washington, Matthew J. Ferber, Catherine Hajek, Elizabeth T. Cirulli, Joseph J. Grzymski
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101826- (2024)
Purpose: This study aimed to evaluate the performance of different genetic screening approaches to identify women at high risk of breast cancer in the general population. Methods: We retrospectively studied 25,591 women with available electronic heal
Externí odkaz:
https://doaj.org/article/91c30b4199254457893c3ce310c06a65
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Diffuse idiopathic skeletal hyperostosis (DISH) is a condition where adjacent vertebrae become fused through formation of osteophytes. The genetic and epidemiological etiology of this condition is not well understood. Here, we implemented a
Externí odkaz:
https://doaj.org/article/ddec5b408f644c55bb1a9971609641df
Publikováno v:
PLoS Genetics, Vol 13, Iss 9, p e1007023 (2017)
Plasmodium parasites, along with their Piroplasm relatives, have caused malaria-like illnesses in terrestrial mammals for millions of years. Several Plasmodium-protective alleles have recently evolved in human populations, but little is known about h
Externí odkaz:
https://doaj.org/article/d281b59593894da5a1b40052b68ee150
Publikováno v:
California Agriculture, Vol 65, Iss 3, Pp 106-111 (2011)
This article focuses on the role of omega-3 fatty acids as precursors for lipid signaling molecules known as oxylipins. Although omega-3 fatty acids are beneficial in autoimmune disorders, inflammatory diseases and heart disease, they are generally u
Externí odkaz:
https://doaj.org/article/7600aa3e4c4f44499f500ffd19b358d7
Combining rare and common genetic variants improves population risk stratification for breast cancer
Autor:
Alexandre Bolze, Daniel Kiser, Kelly M. Schiabor Barrett, Gai Elhanan, Jamie M. Schnell Blitstein, Iva Neveux, Shaun Dabe, Harry Reed, Alexa Anderson, William J. Metcalf, Ekaterina Orlova, Ildiko Thibodeau, Natalie Telis, Ruomu Jiang, Nicole L. Washington, Matthew J. Ferber, Catherine Hajek, Elizabeth T. Cirulli, Joseph J. Grzymski
PurposeIn the United States, breast cancer clinical risk assessments are inconsistent and inequitable. The previous success ofBRCA1andBRCA2screening has demonstrated that genetics could be used to reduce these inequities, if they are available and ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e4080e565505ee57c37a479e96f0bec
https://doi.org/10.1101/2023.05.17.23290132
https://doi.org/10.1101/2023.05.17.23290132
Publikováno v:
The American Journal of Human Genetics. 105:189-197
Women are under-represented in science, technology, engineering, and mathematics (STEM). Despite the recent emphasis on diversity in STEM, our understanding of what drives differences between women and men scientists remains limited. This, in turn, l
Publikováno v:
Genetics
> Advances in genetic technology and biological understanding in the last 100 years have opened a new era of discovery and investigation. In the centennial year of the journal GENETICS , we quantify the remarkable shifts in genetic research through t
Publikováno v:
Nat Ecol Evol
Traces of archaic hominin DNA persist in the human gene pool, but are systematically depleted around genes and other functionally important genomic regions. This suggests that many Neandertal and Denisovan alleles had harmful effects on hybrid fitnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03319dda5b1d16e3416ba70672e653c5
https://doi.org/10.1101/708230
https://doi.org/10.1101/708230
Autor:
Hua Fan-Minogue, Kimberly Van Auken, Mark A. Musen, Michel Dumontier, Jonathan M. Mortensen, Jacob J. Hughey, Natalie Telis
Publikováno v:
Journal of Biomedical Informatics, 60, 199-209. Elsevier Science
Display Omitted Experts identified 16 errors, mainly related to acids and metals.Definition quality and task difficulty affect crowd performance significantly.The number of Internet search results could help identify "easy" crowd tasks.The crowd fits
The protozoan genus Plasmodium causes malaria in dozens of mammal species, including humans, non-human primates, rodents, and bats. In humans, Plasmodium infections have caused hundreds of millions of documented deaths, imposing strong selection on c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0d7cdf2dc704471e20c0196bdd6054